Brazilian Journal of Chemical Engineering,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 18, 2024
Abstract
This
study
presents
a
thorough
overview
of
metal–organic
frameworks’
(MOFs)
utility
as
supports
for
enzyme
immobilization.
It
details
bibliometric
analysis
the
field
from
2014–2023,
based
on
911
Web
Science
articles.
Research
outlines
functional
properties
MOFs,
groups,
and
common
immobilization
techniques.
showcases
diverse
enzyme-MOF
combinations
numerous
applications,
including
industrial
biocatalysis,
medical
diagnostics,
drug
development,
biomass
conversion,
environmental
protection,
biosensor
creation.
Current
development
trends
future
directions
are
identified
through
literature
analysis.
Latent
Dirichlet
Allocation
(LDA)
modeling
revealed
key
research
themes
over
years,
highlighting
shifts
in
focus
towards
advanced
catalytic
methods
adsorption
Additionally,
word
cloud
generated
2024
publications
indicates
an
increasing
emphasis
specialized
applications
involving
ZIFs,
nanoparticles,
magnetic
structures.
Key
perspectives
include
new
MOF
materials,
such
biologically
derived
core–shell
hierarchical
porous
nanoMOFs,
mesoporous
MOFs.
Novel
materials
inspired
by
carriers,
covalent
organic
frameworks
(COFs)
aerogels
(MOAs),
also
highlighted.
Lastly,
emphasizes
potential
multienzymatic
systems
multifunctional
MOF-enzyme
composites,
facilitating
multiple
functionalities
within
single
system.
Gels,
Journal Year:
2024,
Volume and Issue:
10(10), P. 646 - 646
Published: Oct. 10, 2024
Using
free
microorganisms
for
industrial
processes
has
some
limitations,
such
as
the
extensive
consumption
of
substrates
growth,
significant
sensitivity
to
microenvironment,
and
necessity
separation
from
product
and,
therefore,
cyclic
process.
It
is
widely
acknowledged
that
confining
or
immobilizing
cells
in
a
matrix
support
structure
enhances
enzyme
stability,
facilitates
recycling,
rheological
resilience,
lowers
bioprocess
costs,
serves
fundamental
prerequisite
large-scale
applications.
This
report
summarizes
various
cell
immobilization
methods,
including
several
synthetic
(polyvinylalcohol,
polyethylenimine,
polyacrylates,
Eudragit)
natural
(gelatin,
chitosan,
alginate,
cellulose,
agar-agar,
carboxymethylcellulose,
other
polysaccharides)
polymeric
materials
form
thin
films,
hydrogels,
cryogels.
Advancements
production
well-known
antibiotics
like
penicillin
cephalosporin
by
strains
were
discussed.
Additionally,
we
highlighted
cutting-edge
research
related
strain
producers
peptide-based
(polymyxin
B,
Subtilin,
Tyrothricin,
varigomycin,
gramicidin
S,
friulimicin,
bacteriocin),
glusoseamines,
polyene
derivatives.
Crosslinking
agents,
especially
covalent
linkers,
significantly
affect
activity
stability
biocatalysts
(penicillin
G
acylase,
penicillinase,
deacetoxycephalosporinase,
L-asparaginase,
β-glucosidase,
Xylanase,
urease).
The
molecular
weight
polymers
an
important
parameter
influencing
oxygen
nutrient
diffusion,
kinetics
hydrogel
formation,
rigidity,
rheology,
elastic
moduli,
mechanical
properties
crucial
long-term
utilization.
A
comparison
enzymatic
between
immobilized
enzymes
their
native
counterparts
was
explored.
discussion
not
limited
recent
advancements
biopharmaceutical
field,
microorganism
immobilization,
but
also
extended
methods
used
sensor
biosensor
In
this
study,
present
data
on
advantages
over
(bacteria
fungi)
suspension
states
produce
bioproducts
metabolites-such
antibiotics,
enzymes,
precursors-and
determine
efficiency
optimal
conditions
process
parameters
maximize
yield
target
products.
Nanoscale Advances,
Journal Year:
2024,
Volume and Issue:
6(15), P. 3961 - 3977
Published: Jan. 1, 2024
In
this
research,
new
catalytic
applications
of
the
Fe
3
O
4
/
f
-MWCNT-CS-Glu/Ni
II
nanocomposite
have
been
introduced
for
efficient
reduction
and
one-pot
two-step
reductive
Schotten–Baumann-type
acetylation
nitroarenes
in
water.
