ACS Omega,
Journal Year:
2025,
Volume and Issue:
10(1), P. 1207 - 1225
Published: Jan. 3, 2025
Manufacturing
bioactive
materials
for
drug
delivery
involves
developing
that
interact
with
biological
tissues
to
release
drugs
in
a
controlled
and
targeted
manner.
The
goal
is
optimize
therapeutic
efficacy
reduce
side
effects
by
combining
knowledge
from
engineering,
biology,
pharmacology.
This
study
presents
detailed
bibliometric
analysis,
exploring
the
keywords
"manufacturing,"
"bioactive
materials,"
"drug
delivery"
identify
highlight
significant
advancements
field.
From
Web
of
Science,
36,504
articles
were
analyzed,
171
selected
deeper
identifying
key
journals,
countries,
institutions,
authors.
results
field's
interdisciplinary
nature,
grouped
into
four
main
themes,
including
regenerative
medicine,
scaffolds,
three-dimensional
(3D)
printing,
glass,
tissue
engineering.
Future
research
this
area
will
focus
on
more
effective
precise
systems
using
technologies
like
3D
printing
nanotechnology
enhance
customization
control
release,
aiming
efficient
therapies.
Grain & Oil Science and Technology,
Journal Year:
2024,
Volume and Issue:
7(3), P. 196 - 208
Published: June 1, 2024
Wheat
bran,
a
principal
byproduct
of
flour
milling,
stands
as
an
abundant
source
dietary
fiber,
yet
its
economic
potential
remains
under-exploited
in
current
forage
applications.
Arabinoxylan
(AX),
constituting
the
core
emerges
versatile
compound
with
multifaceted
functionalities.
Its
nutritional
significance,
coupled
role
cereal
food
processing,
has
prompted
surge
studies
focusing
on
valorization
wheat
bran
AX.
Moreover,
hydrolyzed
derivative,
arabinoxylan
oligosaccharides
(AXOS),
demonstrates
prebiotic
and
antioxidant
properties,
offering
avenues
to
mitigate
risk
chronic
diseases.
This
review
summarizes
knowledge
AX
terms
processing
properties
multiple
novel
applications
materials
area,
including
biodegradable
packaging
films,
delivery
bioactive
substances
nanoparticles,
manufacture
emulsifiers,
are
also
highlighted
extend
utilization
underscores
immense
AX,
advocating
for
exploitation
not
only
asset
but
primary
ingredient
advanced
materials.
The
synthesis
perspectives
accentuates
utility
thereby
paving
way
sustainable
pathways.
By
unraveling
latent
within
this
paper
advocates
holistic
diverse,
value-added
Peptide Science,
Journal Year:
2025,
Volume and Issue:
117(2)
Published: Feb. 11, 2025
ABSTRACT
This
study
addressed
the
therapeutic
potential
of
dipeptidyl
peptidase
IV
(DPP‐IV)
inhibitory
peptides
obtained
by
whey
protein
hydrolysis
as
natural
adjuvants
to
synthetic
drugs
for
managing
type
2
diabetes
(T2D),
a
condition
marked
insulin
resistance
and
hyperglycemia.
Given
rising
global
incidence
T2D,
exploring
such
bioactive
compounds
is
important
developing
effective
sustainable
treatment
strategies.
The
research
highlights
role
DPP‐IV
inhibitors
in
promoting
secretion
preventing
degradation
incretin
hormones,
with
whey‐derived
emerging
promising
candidates
inhibition.
A
bibliometric
analysis
revealed
steady
growth
publication
output
since
2006,
significant
contributions
from
China,
France,
USA,
underscoring
this
field's
interdisciplinary
nature,
which
spans
food
science,
physiology,
nutrition.
VOSviewer
identified
key
clusters,
including
“Health
Benefits
Biological
Effects
Dairy
Proteins,”
“T2D/drug
therapy,”
areas
like
“insulin/metabolism”
“diet,”
reflecting
growing
interest
these
topics.
findings
emphasize
expanding
focus
on
functional
foods
chronic
disease
management,
highlighting
necessity
further
fully
elucidate
impact
T2D
their
health
initiatives,
emphasizing
importance
integrating
into
support
long‐term
outcomes
need
clinical
trials
validate
efficacy
further.
Applied Sciences,
Journal Year:
2025,
Volume and Issue:
15(7), P. 3516 - 3516
Published: March 23, 2025
This
research
explored
the
potential
of
plant
antimicrobial
compounds
as
natural
alternatives
to
synthetic
antimicrobials
in
food
and
pharmaceutical
industries,
emphasizing
urgent
need
combat
resistance.
It
detailed
various
mechanisms
by
which
these
plant-derived
inhibit
microbial
growth,
including
disrupting
cell
membrane
integrity,
impeding
wall
protein
synthesis,
preventing
biofilm
formation,
ultimately
leading
bacterial
death.
study
highlighted
specific
effects
on
cells,
such
inhibiting
cellular
respiration,
motility,
while
also
modulating
oxygen
consumption
reactive
species
generation,
are
vital
addressing
biofilm-mediated
infections.
Additionally,
can
regulate
expression
virulence
factors
efflux
pumps,
enhancing
antibiotic
efficacy.
A
bibliometric
analysis
revealed
a
growing
trend
output
international
collaboration,
particularly
from
China
United
States,
with
key
journals
“Frontiers
Microbiology”
“Antimicrobial
Agents
Chemotherapy.”
The
identified
six
clusters
related
research,
underscoring
for
further
investigation
into
applications
bioactive
compounds.
In
conclusion,
understanding
action
is
important
their
effective
application
combating
Materials,
Journal Year:
2024,
Volume and Issue:
17(17), P. 4220 - 4220
Published: Aug. 27, 2024
In
recent
years,
a
growing
demand
for
biomaterials
has
been
observed,
particularly
applications
in
bone
regenerative
medicine.
Bone
tissue
engineering
(BTE)
aims
to
develop
innovative
materials
and
strategies
repairing
regenerating
defects
injuries.
Polysaccharides,
due
their
biocompatibility,
biodegradability
as
well
bioactivity,
have
emerged
promising
candidates
scaffolds
or
composite
systems
BTE.
Polymers
combined
with
bioactive
ceramics
can
support
osteointegration.
Calcium
phosphate
(CaP)
be
broad
choice
an
inorganic
phase
that
stimulates
the
formation
of
new
apatite
layers.
This
review
provides
comprehensive
analysis
based
on
selected
polysaccharides
used
engineering,
highlighting
synthesis,
properties
applications.
Moreover,
applicability
produced
biocomposites
analyzed,
trends
modifying
endowing
them
functionalizations.
The
effects
these
composites
mechanical
properties,
biocompatibility
osteoconductivity
were
critically
analyzed.
article
summarizes
latest
manufacturing
methods
developments
polysaccharide-based
cartilage
regeneration
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 14, 2024
This
chapter
addressed
the
problem
of
understanding
role
probiotics
in
managing
metabolic
syndrome.
Therefore,
objective
was
to
analyze
clinical
evidence
surrounding
using
and
prebiotics
for
syndrome
through
a
bibliometric
analysis
evaluate
impact
dietary
interventions
on
microbiota.
The
most
significant
results
from
data
reveal
that
have
beneficial
effect
various
aspects
syndrome,
including
blood
pressure,
glucose
metabolism,
lipid
profiles,
inflammatory
biomarkers.
Visualization
techniques
such
as
word
clouds
scientometric
mapping
illustrate
thematic
landscape
distribution
research
articles,
highlighting
emphasis
cardiovascular
health
modulation
women’s
gut
Despite
substantial
supporting
effects
probiotics,
discrepancies
across
studies
were
found,
indicating
variability
outcomes,
potentially
due
differences
specific
probiotic
strains
used
their
dosages.
In
conclusion,
study
provides
comprehensive
overview
favorable
It
suggests
could
be
viable
strategy
health.
Moreover,
this
book
emphasizes
importance
standardization
improving
reliability
comparability
different
studies.
