The Aggravating Role of Failing Neuropeptide Networks in the Development of Sporadic Alzheimer’s Disease DOI Open Access
Miklós Jászberényi,

Balázs Thurzó,

Arumugam R. Jayakumar

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(23), P. 13086 - 13086

Published: Dec. 5, 2024

Alzheimer's disease imposes an increasing burden on aging Western societies. The disorder most frequently appears in its sporadic form, which can be caused by environmental and polygenic factors or monogenic conditions of incomplete penetrance. According to the authors, majority cases, represents aggravated form natural central nervous system. It characterized decreased elimination amyloid β

Language: Английский

Sleep and Immune System Crosstalk: Implications for Inflammatory Homeostasis and Disease Pathogenesis DOI Creative Commons
Krishna Kumar Singh, Shampa Ghosh,

Anisha Bhola

et al.

Annals of Neurosciences, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 20, 2024

Background Sleep and immune function are interconnected aspects of health that mutually impact each other in disease development inflammatory homeostasis. Different immunology regulated by different sleep characteristics, impacting on specific including cytokine production T-cell activity. Ongoing disruptions have been linked to heightened inflammation suspected the pathogenesis course a range life-style-related illnesses, diabetes neurodegenerative diseases. Summary This review provides comprehensive overview knowledge interaction with system, its modulation balance, many It emphasizes how deficiency compromises means systemic, low-grade response, while adequate promotes intense responses thus enables efficient pathogen clearance maintenance memory. The mutual influence system underlines critical involvement preservation disease. Key Message plays an indispensable role health, mediating efficiency regulation inflammation. Chronic deprivation can result substantially contributes onset exacerbation metabolic disorders. intimate linkage between be one strategic approach therapy, improving outcomes leveraging this sleep-immune connection.

Language: Английский

Citations

7
Relationship between long-term shift work; night work; sleep deficiency and stroke: A systematic review and meta-analysis DOI

Xiaxia Jin,

Yifan Yang, Feng Zhou

et al.

Sleep Medicine, Journal Year: 2024, Volume and Issue: 119, P. 499 - 504

Published: May 17, 2024

Language: Английский

Citations

4
SLEEP DISORDERS AND RISK OF ALZHEIMER'S DISEASE: A TWO-WAY ROAD DOI

Rafael Antônio Vicente Lacerda,

Janaína Aparecida Favero Desio, Camila Marciele Kammers

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 102514 - 102514

Published: Sept. 1, 2024

Language: Английский

Citations

4
Association of Sleep Duration and Daytime Napping With Risk of Hyperuricemia: A Systematic Review and Meta‐Analysis DOI
Xinwen Zhang, Guangcheng Wei,

Xieyu Zhang

et al.

International Journal of Rheumatic Diseases, Journal Year: 2025, Volume and Issue: 28(1)

Published: Jan. 1, 2025

ABSTRACT Background Hyperuricemia (HUA), marked by elevated serum urate levels, is increasingly prevalent worldwide. The relationship between lifestyle factors such as sleep duration, daytime napping, and HUA risk remains unclear. Although some studies suggest that variables, including short or long durations may influence uric acid results are inconsistent. Methods A systematic review meta‐analysis was performed according to the PRISMA guidelines. Databases PubMed, Embase, Web of Science, Cochrane Library were searched until February 2024. data extracted, quality study assessed independently two reviewers. Results Ten involving a total 231 978 participants included. Short duration related higher (odds ratio (OR) 1.10, 95% confidence interval (CI): 1.03–1.18), while had no significant effect (OR 0.98, CI: 0.89–1.07). napping statistically significant(OR 1.34, 1.12–1.61). Conclusions prolonged associated with an increased HUA. These findings patterns should be considered in interventions for prevention. Further research required establish causal relationships.

Language: Английский

Citations

0
Exploring the nexus: Sleep disorders, circadian dysregulation, and Alzheimer’s disease DOI
Pratima Khandayataray, Meesala Krishna Murthy

Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Unveiling the Protective Roles of Melatonin on Glial Cells in the Battle Against Alzheimer’s Disease—Insights from In Vivo and In Vitro Studies DOI

Nopdanai Sirimaharaj,

Kitti Thiankhaw,

Nipon Chattipakorn

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Language: Английский

Citations

0
A interconexão entre a doença de Alzheimer e distúrbios do sono: implicações clínicas e terapêuticas DOI Open Access

Gabriel Marcos Theodoro Cardoso,

Kamily Evan de Castro Mendes,

Isabelly França Loss

et al.

Brazilian Journal of Health Review, Journal Year: 2024, Volume and Issue: 7(4), P. e72066 - e72066

Published: Aug. 21, 2024

Considerando a crescente evidência sobre influência da qualidade do sono na Doença de Alzheimer e necessidade entender melhor essa relação, o presente estudo visa explorar como distúrbios afetam progressão identificar possíveis intervenções terapêuticas. Objetiva-se avaliar impacto privação interrupção saúde cerebral no desenvolvimento Alzheimer. Para tanto, foi realizada uma revisão abrangente literatura existente, incluindo estudos observacionais análises Os resultados indicam que comprometem formação novas memórias eliminação toxinas cerebrais, beta-amiloide, exacerbando os sintomas A análise mostrou boa é essencial para manter sistema nervoso central pode ter um efeito positivo mitigação dos doença. Desse modo, conclui-se promoção melhorar sono, rotinas consistentes, atividade física dietas equilibradas, crucial manejo Além disso, tratamentos farmacológicos regulam neurotransmissores associados ao podem oferecer benefícios significativos. Futuras pesquisas devem focar em metodologias robustas validar essas descobertas abordagens

Citations

0
The Aggravating Role of Failing Neuropeptide Networks in the Development of Sporadic Alzheimer’s Disease DOI Open Access
Miklós Jászberényi,

Balázs Thurzó,

Arumugam R. Jayakumar

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(23), P. 13086 - 13086

Published: Dec. 5, 2024

Alzheimer's disease imposes an increasing burden on aging Western societies. The disorder most frequently appears in its sporadic form, which can be caused by environmental and polygenic factors or monogenic conditions of incomplete penetrance. According to the authors, majority cases, represents aggravated form natural central nervous system. It characterized decreased elimination amyloid β

Language: Английский

Citations

0