Pleural abnormalities in COVID-19: a narrative review

Journal of Thoracic Disease, Journal Year: 2021, Volume and Issue: 13(7), P. 4484 - 4499

Published: July 1, 2021

This narrative review aims to provide a detailed overview of pleural abnormalities in patients with coronavirus disease 19 or COVID-19.

Language: Английский

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Narrative review of the relationship between COVID-19 and PJP: does it represent coinfection or colonization?

Infection, Journal Year: 2021, Volume and Issue: 49(6), P. 1079 - 1090

Published: May 31, 2021

Language: Английский

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Macklin effect on baseline chest CT scan accurately predicts barotrauma in COVID-19 patients

Respiratory Medicine, Journal Year: 2022, Volume and Issue: 197, P. 106853 - 106853

Published: April 21, 2022

Language: Английский

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Clinical use of Macklin-like radiological sign (Macklin effect): A systematic review

Respiratory Medicine, Journal Year: 2023, Volume and Issue: 210, P. 107178 - 107178

Published: Feb. 28, 2023

Language: Английский

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Pneumothorax and/or Pneumomediastinum Worsens the Prognosis of COVID-19 Patients with Severe Acute Respiratory Failure: A Multicenter Retrospective Case-Control Study in the North-East of Italy

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(21), P. 4835 - 4835

Published: Oct. 21, 2021

Pneumothorax (PNX) and pneumomediastinum (PNM) are potential complications of COVID-19, but their influence on patients' outcomes remains unclear. The aim the study was to assess incidence, risk factors, severe COVID-19 complicated with PNX/PNM.A retrospective multicenter case-control analysis conducted in patients admitted for respiratory failure intermediate care units Treviso area, Italy, from March 2020 April 2021. Clinical characteristics without PNX/PNM were compared.Among 1213 patients, PNX and/or PNM incidence 4.5%. Among these, 42% had PNM, 33.5% only PNX, 24.5% PNM. showed higher in-hospital (p = 0.02) 90-days mortality 0.048), longer hospitalization length 0.002) than PNX/PNM. At occurrence, one-third subjects not mechanically ventilated, support similar control group. occurrence associated symptom before hospital admission 0.005) lower levels blood lymphocytes 0.017).PNX/PNM a worse prognosis terms hospitalization. Although they more frequent ventilated can occur non-ventilated, suggesting that mechanisms other barotrauma might contribute presentation.

Language: Английский

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Spontaneous pneumomediastinum, pneumothorax and subcutaneous emphysema in critically ill COVID-19 patients: A systematic review

Pakistan Journal of Medical Sciences, Journal Year: 2022, Volume and Issue: 38(3)

Published: Jan. 15, 2022

Objectives: COVID-19 patients develop Life-threatening complications like pneumomediastinum/pneumothorax and emphysema which might experience prolonged hospital stays additional costs be imposed on the patient health system. The clinical features outcomes of mechanically ventilated with infection who a pneumothorax, pneumomediastinum subcutaneous has not been rigorously described or compared to those do these complications. So systematic review studies conducted this subject was carried out better manage by investigating underlying factors in patients. Methods: search between early January late December 2020 databases including PubMed, Scopus, ProQuest, Embase, Cochrane Library, Web Science, using following keywords their combinations: Complication, Pneumothorax, Pneumomediastinum, Pneumopericardium, Subcutaneous Emphysema. extracted were screened separately two researchers based PRISMA statement. After eliminating duplicate studies, title, abstract, full text remaining reviewed. Disagreements screening selection resolved consensus through third-party opinion. Results: A total 793 articles retrieved literature search, 99 139 finally included mortality found have significant relationship positive pressure ventilation (P=0.0001). There no patients’ death chest tube insertion (P=0.2) interval time from onset symptoms diagnosis pneumothorax (P=0.7). mean age higher deceased cases, difference observed statistically (P=0.001). Conclusion: With expansion our understanding COVID-19, recognition uncommon especially is crucial. Although we couldn’t find causal association death, as it limited many variables such studies’ design, incomplete outcome data more information about associated risk factors, recommend performing well-designed describe pneumothoraxes› incidence, doi: https://doi.org/10.12669/pjms.38.3.5529 How cite this:Shahsavarinia K, Rahvar G, Soleimanpour H, Saadati M, Vahedi L, Mahmoodpoor A. Spontaneous pneumomediastinum, critically ill patients: review. Pak J Med Sci. 2022;38(3):---------. This an Open Access article distributed under terms Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), permits unrestricted use, distribution, reproduction any medium, provided original work properly cited.

Language: Английский

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Examining the Clinical Prognosis of Critically Ill Patients with COVID-19 Admitted to Intensive Care Units: A Nationwide Saudi Study

Medicina, Journal Year: 2021, Volume and Issue: 57(9), P. 878 - 878

Published: Aug. 26, 2021

Backgroundand Objectives: COVID-19 is a novel infectious disease caused by single-stranded RNA coronavirus called severe acute respiratory syndrome 2 (SARS-CoV-2). We aimed to conduct nationwide multicenter study determine the characteristics and clinical prognostic outcome of critically ill patients admitted intensive care units (ICUs). Materials Methods: This cohort retrospective conducted in twenty Saudi hospitals. Results: An analysis 1470 demonstrated that majority were male with mean age 55.9 ± 15.1 years. Most our presented shortness breath (SOB) (81.3%), followed fever (73.7%) cough (65.1%). Diabetes hypertension most common comorbidities (52.4% 46.0%, respectively). Multiple complications observed substantially more among non-survivors. The length frequency mechanical ventilation use significantly greater (83%) non-survivors compared survivors (31%). Sequential Organ Failure Assessment (SOFA) score was 6 5. overall mortality rate associated had diabetes, ischemic heart 41.8%. Conclusion: Age; pre-existing medical history hypertension, diabetes disease; smoking cigarettes; BMI ≥ 29; long ICU stay; need ventilatory support; high SOFA score; fungal co-infections extracorporeal membrane oxygenation (ECMO) key predicted population.

Language: Английский

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Risk Factors, Characteristics, and Outcome in Non-Ventilated Patients with Spontaneous Pneumothorax or Pneumomediastinum Associated with SARS-CoV-2 Infection

International Journal of General Medicine, Journal Year: 2022, Volume and Issue: Volume 15, P. 489 - 500

Published: Jan. 1, 2022

Spontaneous pneumothorax (SP) and spontaneous pneumomediastinum (SPM) have frequently been cited as complications associated with coronavirus disease 2019 (COVID-19) pneumonia, especially poor prognosis in mechanically ventilated patients. The current literature is controversial regarding the potential risk factors for developing SP or SPM (SP-SPM) non-ventilated COVID-19 Our research addressed a twofold objective: (a) to investigate characteristics of patients SP-SPM (both without COVID-19) compare them sole COVID-19; (b) quantify in-hospital mortality COVID-19.A retrospective case-control study was conducted emergency departments (ED) two tertiary hospitals Timisoara, Romania, over one year (1st April 2020‒31st March 2021; 64,845 records total) 70 cases were identified SARS-CoV-2 positives negatives). control group comprised no SP-SPM, included at 2:1 ratio. Logistic regression employed age, COVID-19.SP-SPM connected prolonged hospitalization, higher percentage intensive care admission, mortality. increased odds death by almost four times same gender, smoking status, infection: OR = 3.758, 95% CI (1.443-9.792). Each additional age added 9.4% risk: 1.094, (1.054-1.135).ED physicians should acknowledge these risks when attending SP-SPM.

Language: Английский

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Risk factors of pneumothorax and pneumomediastinum in COVID-19: a matched case–control study

BMC Infectious Diseases, Journal Year: 2023, Volume and Issue: 23(1)

Published: March 7, 2023

Abstract Background During the novel coronavirus disease-2019 pandemic, a considerable number of pneumothorax (PNX)/pneumomediastinum (PNM) associated with COVID-19 have been reported, and incidence is higher in critically ill patients. Despite using protective ventilation strategy, PNX/PNM still occurs patients on invasive mechanical (IMV). This matched case–control study aims to identify risk factors clinical characteristics COVID-19. Methods retrospective enrolled adult COVID-19, admitted critical care unit from March 1, 2020, January 31, 2022. were compared, 1–2 ratio, without PNX/PNM, for age, gender, worst National Institute Allergy Infectious Diseases ordinal scale. Conditional logistic regression analysis was performed assess Results 427 during period, 24 diagnosed PNX/PNM. Body mass index (BMI) significantly lower case group (22.8 kg/m 2 24.7 ; P = 0.048). BMI statistically significant factor univariate conditional [odds ratio (OR), 0.85; confidence interval (CI), 0.72–0.996; 0.044]. For IMV support, showed statistical significance duration symptom onset intubation (OR, 1.14; CI, 1.006–1.293; 0.041). Conclusions Higher tended show effect against due delayed application might be contributive this complication.

Language: Английский

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The Effect of Comorbidities and Complications on COVID-19 Mortality: A Detailed Retrospective Study in Western Romania

Journal of Personalized Medicine, Journal Year: 2023, Volume and Issue: 13(11), P. 1552 - 1552

Published: Oct. 29, 2023

COVID-19 continues to impact global health systems even after being declared over, with some patients exhibiting severe complications linked pre-existing conditions. This study aimed investigate the association between comorbidities, complications, and survival outcomes among survivors in Western Romania. Our hypothesis posited that comorbidities significantly influence rates. We conducted a retrospective analysis of 1948 admitted from January December 2021, 192 selected for detailed based on inclusion exclusion criteria. The severity was classified according WHO guidelines, conditions like hypertension obesity were defined using criteria European Society Hypertension (ESH), Cardiology (ESC), WHO, respectively. Among patients, 33 had mild, 62 moderate, 97 COVID-19. median age across groups 63.2 years. Patients undergoing tracheostomy mortality rate 83.3% versus 22.2% non-tracheostomy (p < 0.001) presented higher lung injury, hospitalization duration, complications. Remarkably, tracheostomized 17.50 times more likely succumb disease (95% CI 4.39–116.91, p 0.001). Furthermore, pneumothorax increased risk (OR 22.11, 95% 5.72–146.03, Intriguingly, certain grade I II showed protective effect against mortality, whereas type 2 diabetes mellitus (univariate OR 2.89, = presence impacts rates Notably, tracheostomy, pneumothorax, T2DM associated mortality. underscores importance personalized patient care provides insights healthcare policymakers Romania improve clinical management strategies.

Language: Английский

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