A review of the molecular mechanisms of acaricide resistance in mites and ticks

Insect Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 159, P. 103981 - 103981

Published: June 28, 2023

The Arachnida subclass of Acari comprises many harmful pests that threaten agriculture as well animal health, including herbivorous spider mites, the bee parasite Varroa, poultry mite Dermanyssus and several species ticks. Especially in agriculture, acaricides are often used intensively to minimize damage they inflict, promoting development resistance. Beneficial predatory mites biological control also subjected acaricide selection field. use new genetic genomic tools such genome transcriptome sequencing, bulked segregant analysis (QTL mapping), reverse genetics via RNAi or CRISPR/Cas9, have greatly increased our understanding molecular mechanisms resistance Acari, especially Tetranychus urticae which emerged a model species. These techniques allowed uncover validate mutations larger range In addition, provided an impetus start elucidating more challenging questions on gene regulation detoxification associated with

Language: Английский

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The molecular mechanisms of insecticide resistance in aphid crop pests

Insect Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 156, P. 103937 - 103937

Published: April 5, 2023

Aphids are a group of hemipteran insects that include some the world's most economically important agricultural pests. The control pest aphids has relied heavily on use chemical insecticides, however, evolution resistance poses serious threat to their sustainable control. Over 1000 cases have now been documented for involving remarkable diversity mechanisms that, individually or in combination, allow toxic effect insecticides be avoided overcome. In addition its applied importance as growing human food security, insecticide also offers an exceptional opportunity study under strong selection and gain insight into genetic variation fuelling rapid adaptation. this review we summarise biochemical molecular underlying aphid pests worldwide insights topic provided genomic architecture adaptive traits.

Language: Английский

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Comprehensive analysis of the overexpressed cytochrome P450-based insecticide resistance mechanism in Spodoptera litura

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 461, P. 132605 - 132605

Published: Sept. 22, 2023

Language: Английский

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Characterization and functional analysis of UDP-glycosyltransferases reveal their contribution to phytochemical flavone tolerance in Spodoptera litura

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129745 - 129745

Published: Jan. 28, 2024

Language: Английский

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Spirotetramat resistance inMyzus persicae(Sulzer) (Hemiptera: Aphididae) and its association with the presence of theA2666Vmutation

Pest Management Science, Journal Year: 2022, Volume and Issue: 78(11), P. 4822 - 4831

Published: July 28, 2022

Abstract BACKGROUND Chemicals are widely used to protect field crops against aphid pests and aphid‐borne viral diseases. One such species is Myzus persicae (Sulzer), a global pest that attacks broad array of agricultural transmits many economically damaging plant viruses. This has evolved resistance large number insecticide compounds as result widespread repeated chemical use in parts the world. In this study, we investigated evolution new protection product, spirotetramat, following reported control failures. RESULTS Our study provides clear phenotypic genotypic evidence spirotetramat populations M. from Australia. We show there cross‐resistance other insecticides within same group, namely spiromesifen spirodiclofen. also demonstrate associated with previously mutation, A2226V target site acetyl‐CoA carboxylase. genetic analysis found all resistant belong multi‐locus clonal type carry which appears be inherited dominant trait species. CONCLUSION findings provide insight into conferred by have implications for Australia worldwide. A diagnostic assay developed should serve valuable tool future monitoring support implementation management strategies. © 2022 The Authors. Pest Management Science published John Wiley & Sons Ltd on behalf Society Chemical Industry.

Language: Английский

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Contribution of UDP-glycosyltransferases to chlorpyrifos resistance in Nilaparvata lugens

Pesticide Biochemistry and Physiology, Journal Year: 2022, Volume and Issue: 190, P. 105321 - 105321

Published: Dec. 20, 2022

Language: Английский

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Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta

Insect Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 159, P. 103983 - 103983

Published: June 26, 2023

The tomato leafminer, Tuta absoluta, is an invasive crop pest that has evolved resistance to many of the insecticides used for its control. To facilitate investigation underpinning mechanisms in this species we generated a contiguous genome assembly using long-read sequencing data. We leveraged genomic resource investigate genetic basis diamide insecticide chlorantraniliprole Spanish strains T. absoluta exhibit high levels insecticide. Transcriptomic analyses revealed that, these strains, not associated with previously reported target-site mutations target-site, ryanodine receptor, but rather marked overexpression (20- >100-fold) gene encoding UDP-glycosyltransferase (UGT). Functional expression UGT, UGT34A23, via ectopic Drosophila melanogaster demonstrated it confers strong and significant vivo. resources study provide powerful further research on absoluta. Our findings will inform development sustainable management strategies important pest.

Language: Английский

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Expression profile of the entire detoxification gene inventory of the western honeybee, Apis mellifera across life stages

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 192, P. 105410 - 105410

Published: March 28, 2023

The western honeybee, Apis mellifera, is a managed pollinator of many crops and potentially exposed to wide range foreign compounds, including pesticides throughout its life cycle. Honeybees as well other insects recruit molecular defense mechanisms facilitate the detoxification xenobiotic compounds. inventory genes (DETOXome) comprised five protein superfamilies: cytochrome P450 monooxygenases (P450), carboxylesterases, glutathione S-transferases (GST), UDP-glycosyl transferases (UGT) ATP-binding cassette (ABC) transporters. Here we characterized gene expression profile entire honeybee DETOXome by analyzing 47 transcriptomes across cycle, different larval instars, pupae, adults. All stages were separated principal component analysis, K-means clustering revealed distinct temporal patterns expression. Indeed, >50% found in one cluster follows strikingly similar profiles, i.e., increased during development, followed sharp decline after pupation steep increase again This includes 29 dominated CYP3 CYP4 clan members, 15 ABC transporter mostly belonging ABCC subfamily 13 carboxylesterase almost all members involved dietary/detox hormone/semiochemical processing. RT-qPCR analysis selected from families high levels various tissues, especially Malpighian tubules, fatbody midgut, supporting view that these tissues are essential for metabolic clearance environmental toxins pollutants honeybees. Our study meant spark further research on basis this critical better understand evaluate negative impacts toxic substances. Additionally, set collected analyzed provides valuable resource future disciplines.

Language: Английский

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Functional analysis of UDP-glycosyltransferase genes conferring indoxacarb resistance in Spodoptera litura

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 196, P. 105589 - 105589

Published: Aug. 25, 2023

Language: Английский

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Nicotinamide deficiency promotes imidacloprid resistance via activation of ROS/CncC signaling pathway-mediated UGT detoxification in Nilaparvata lugens

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 926, P. 172035 - 172035

Published: March 31, 2024

Language: Английский

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