Doxycycline Drug Release Property of Glutaraldehyde Crosslinked Hydrogel DOI Creative Commons

P Kavish,

Kalpana Ramachandran, Vinay Kumar

et al.

Journal of Pharmacy And Bioallied Sciences, Journal Year: 2024, Volume and Issue: 16(Suppl 2), P. S1204 - S1206

Published: April 1, 2024

A BSTRACT Delayed wound healing is one of the most common problems associated with diabetic patients. There are several factors delayed healing. It has been observed that if not cured takes a long time. This reason researchers engaged in developing sustainable, biodegradable, biocompatible, and effective wound-healing dressings. However, it traditional bandages have drawbacks such as allergies less efficiency absorption exudate. To fill gap, hydrogels developed recently which higher capacity. In addition, they pose slow drug release properties. Therefore, present study was conducted to prepare an promising hydrogel high

Language: Английский

Fabrication and characterization of a novel magnetic nanostructure based on pectin–cellulose hydrogel for in vitro hyperthermia during cancer therapy DOI Creative Commons
Farnoush Ahmadpour, Fatemeh Ganjali, Fateme Radinekiyan

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(19), P. 13676 - 13684

Published: Jan. 1, 2024

Herein, a new magnetic nanobiocomposite based on synthesized cross-linked pectin-cellulose hydrogel (cross-linked Pec-Cel hydrogel) substrate was designed and synthesized. The formation of the with calcium chloride agent its magnetization process caused efficient nanobiocomposite. Several spectral analytical techniques, including FTIR, SEM, VSM, TGA, XRD, EDX analyses, were performed to confirm characterize structural features (magnetic nanobiocomposite). Based SEM images, prepared Fe3O4 nanoparticles (MNPs) uniformly dispersed in context, representing an average particle size between 50.0 60.0 nm. XRD pattern also confirms crystallinity All constituent elements their distribution have been depicted analysis VSM curves confirmed superparamagnetic behavior MNPs saturation 77.31 emu g-1 48.80 g-1, respectively. thermal stability authenticated ca. 800 °C TGA thermogram. Apart from analyzing properties nanobiocomposite, different concentrations (0.5 mg mL-1, 1.0 2.0 5.0 10.0 mL-1) this nanostructure exposed alternating field (AMF) at frequencies (100.0 MHz, 200.0 300.0 400.0 MHz) evaluate capacity for vitro hyperthermia process; addition, highest specific absorption rate (126.0 W g-1) obtained by least concentration mL-1).

Language: Английский

Citations

4

Functional Hydrogel Interfaces for Cartilage and Bone Regeneration DOI Open Access

Yucheng Cao,

Changyi Liu,

W. Ye

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

Abstract Effective treatment of bone diseases is quite tricky due to the unique nature tissue and complexity repair process. In combination with biological materials, cells factors can provide a highly effective safe strategy for regeneration, especially based on these multifunctional hydrogel interface materials. However, itis still challenge formulate materials fascinating properties (e.g., activity, controllable biodegradability, mechanical strength, excellent cell/tissue adhesion, release properties) their clinical applications in complex processes. this review, we will highlight recent advances developing functional hydrogels. We then discuss barriers producing without sacrificing inherent properties, potential cartilage are discussed. Multifunctional serve as fundamental building block engineering.

Language: Английский

Citations

0

Network‐Remodeling, Electroactive and Antibacterial Cryogel with Tissue Sealing and Pro‐Coagulant Activity for Hemostasis and Skin Wound Healing DOI Open Access

Jinlong Luo,

Zhengying Wu,

Xin Zhao

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Abstract Developing network‐remodeling, electroactive and antibacterial cryogel with tissue sealing pro‐coagulant activity for wound repair hemostasis remains challenging. Here, quaternized chitosan‐graft‐polyaniline (QCSP), oxidized dextran (OD), benzaldehyde‐terminated Pluronic F127 are used to prepare dressings (QP/OD/PF) network remodeling, electroactivity, antibacterial, antioxidation, blood concentration effect via in situ dual Schiff base crosslinking. The exhibits conductivity remodeling after water absorption demonstrates degradation, rapid swelling, excellent adhesion, biocompatibility, photothermal property. Besides, the hemostatic property of is confirmed mouse liver puncture bleeding model, rat cruciate incision perforation model. effect, as well activation platelets cells by cryogel, confirmed. This functionality successfully utilized biologically active clot/cryogel composite dressing (B‐QP/OD/PF) further promote skin healing. All results closure ratio, histological examination, immunofluorescence staining, collagen deposition confirm that B‐QP/OD/PF superior QP/OD/PF other groups promoting full‐thickness defect opens up a new direction development

Language: Английский

Citations

0

A brief strategy for the preparation of silk fibroin-copper sulfide-based electrospun nanofibrous membranes with photothermal antimicrobial properties to accelerate the infected wound healing DOI Creative Commons
Rui Cai, Jiayu Zhao,

Peirong Zhou

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101605 - 101605

Published: Feb. 21, 2025

Language: Английский

Citations

0

The role of hydrogels in wound healing DOI
Barbara Vigani, Caterina Valentino, Marco Ruggeri

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 443 - 476

Published: Jan. 1, 2025

Language: Английский

Citations

0

Harnessing Nature's Power: Plant and Polymeric‐Based Antibacterials as Potential Therapeutics for Infectious Skin Wound Healing DOI Open Access

Rasoul Kheradmandi,

Sepehr Zamani, Mohammad Kamalabadi‐Farahani

et al.

Biopolymers, Journal Year: 2025, Volume and Issue: 116(2)

Published: March 1, 2025

ABSTRACT This comprehensive review explores the potential of plant‐ and biopolymeric‐based antibacterials as innovative therapeutic agents for infectious skin wound healing. By researching antibacterial properties various plants, highlights their application in tissue engineering. Beyond reviewing plant extracts, article delves into limitations these natural compounds face, such hydrophilicity, drug release rates, cell attachment, scaffold stability when integrated engineering constructs. The also emphasizes role biopolymeric materials, hydrogel optimization, crosslinkers to improve performance. provides a roadmap future research by addressing critical factors construction. In end, it aims guide development more effective dressings scaffolds, combining power plants with advanced materials enhanced healing therapies.

Language: Английский

Citations

0

Cartilage-inspired biocompatible double network PVA based hydrogels: A critical comparison of the role of agarose, chitosan, and silk fibroin additives DOI
Leonarda Vukonić, Rosa Maria Nothnagel, Felix Groß

et al.

Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112318 - 112318

Published: March 1, 2025

Language: Английский

Citations

0

Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing DOI
Xiuwen Zhang, Li Ren,

Shuangying Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142280 - 142280

Published: March 1, 2025

Language: Английский

Citations

0

Muscle-inspired lamellar chitosan sponge with photothermal antibacterial and antioxidant properties for hemostasis and accelerated bacteria infected wound healing DOI
Xueyu Jiang,

Lingling Yuan,

Piaoye Ming

et al.

Applied Materials Today, Journal Year: 2023, Volume and Issue: 35, P. 101992 - 101992

Published: Nov. 16, 2023

Language: Английский

Citations

8

Advances in polymer-based scaffolding for enhanced wound healing: a comprehensive review DOI

Tamnna,

Teenu Sharma, Roopal Mittal

et al.

International Journal of Polymeric Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: July 1, 2024

A wound is an immediate injury caused by a forceful impact, trauma, or internal resulting in the rupture of epidermis. Pathophysiological lesions can be classified as acute chronic depending upon time their occurrence. Historically, dressings have been employed method treating both and lesions. These form physical barrier between external environment, thus preventing bacterial infections. However, absence regular dressing changes increases likelihood infection. As result dressing's prior adhesion to incision, its removal cause unwarranted discomfort granule tissue loss. Moreover, other approaches used conventionally are relatively less effective. limitations prompted investigation substitutes that could reduce granulation loss, alleviate pain, deliver adequate oxygen facilitate repair. Scaffolding potentially effective strategy treatment incisions. Various naturally occurring synthetic polymers being explored for purpose. The objective this review provide concise overview physiochemical properties biomedical applications prevailing derived skin regeneration healing, along with various fabrication techniques scaffolds.

Language: Английский

Citations

2