Advanced Drug Carriers: A Review of Selected Protein, Polysaccharide, and Lipid Drug Delivery Platforms

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 786 - 786

Published: Jan. 8, 2024

Studies on bionanocomposite drug carriers are a key area in the field of active substance delivery, introducing innovative approaches to improve therapy. Such play crucial role enhancing bioavailability substances, affecting therapy efficiency and precision. The targeted delivery drugs sites action minimization toxicity body is becoming possible through use these advanced carriers. Recent research has focused structures based biopolymers, including lipids, polysaccharides, proteins. This review paper description lipid-containing nanocomposite (including liposomes, lipid emulsions, nanoparticles, solid nanostructured carriers), polysaccharide-containing alginate cellulose), protein-containing (e.g., gelatin albumin). It was demonstrated many investigations that such show ability load therapeutic substances efficiently precisely control release. They also desirable biocompatibility, which promising sign for their potential application development indicates novel approach improving processes, contribute significant advances pharmacology, efficacy while minimizing side effects.

Language: Английский

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Recent advances in synergistic use of GQD-based hydrogels for bioimaging and drug delivery in cancer treatment

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(21), P. 5039 - 5060

Published: Jan. 1, 2024

Hydrogel loaded GQDs can be used for targeted bioimaging in specific diseases, including cancer, due to their small size and biocompatibility. have potential application cancer therapy ability absorb radiation make them suitable photothermal photodynamic therapies.

Language: Английский

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The role of graphene quantum dots in cutting‐edge medical therapies

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(9)

Published: Sept. 1, 2024

Abstract Graphene quantum dots (GQDs), owing to their unique optical, electrical, and chemical properties, have emerged as promising nanomaterials for various biomedical applications. This review provides a comprehensive overview of the latest advancements in utilization GQDs tissue engineering, wound healing, drug delivery systems, other therapies. The inherent properties GQDs, including high biocompatibility, tunable photoluminescence, significant surface area, make them ideal candidates enhancing medical treatments diagnostics. In improve mechanical biological performance scaffolds, promoting cell proliferation differentiation. For enhance antimicrobial activity facilitate faster regeneration. Their potential DDS is highlighted by ability deliver therapeutic agents efficiently, ensuring targeted controlled release. Additionally, play crucial role therapies, particularly cancer treatment, efficacy reducing side effects. While offer diagnostics, challenges such understanding long‐term cytotoxicity at higher concentrations, need standardized synthesis methods remain critical areas further research. also discusses future directions opportunities emphasizing transformative advancing modern healthcare solutions. insights presented here contribute expanding field GQD research, highlighting significantly patient outcomes drive innovations.

Language: Английский

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Carbon-based nanomaterials: interactions with cells, brain therapies, and neural sensing

Deleted Journal, Journal Year: 2025, Volume and Issue: 20(1)

Published: Feb. 21, 2025

Abstract Carbon nanomaterials (CNMs) are characterized by their extensive surface area and extraordinary electronic, thermal, chemical properties, offering an innovative potential for biomedical applications. The physicochemical properties of CNMs can be fine-tuned through functionalization to design the bio-nano interface, allowing controlled biocompatibility or specific bioactivity. This versatility offers a transformative approach addressing inherent limitations conventional brain therapies, which frequently demonstrate low efficacy significant adverse effects. review delves into recent advances in understanding intricate interactions between carbon nanostructures cellular systems, highlighting activity therapy neuronal sensing. We provide comprehensive analysis key nanostructures, including few-layer graphene (FLG), oxide (GO), quantum dots (GQD), single- multi-walled nanotubes (SWCNT MWCNT), nanohorns (CNH), nanodiamonds (CNDs), fullerenes (C 60 ). Their unique atomic configurations modifications examined, revealing underlying mechanisms that drive highlights how deep cells catalyze neurotherapeutic solutions. By leveraging address critical challenges such as crossing blood–brain barrier, improving therapeutic accuracy, minimizing side These have significantly improve treatment outcomes disorders, paving way new era targeted effective neurological interventions.

Language: Английский

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Silver Nanocubes/Nano Mica Platelets Flexible Nanohybrid Substrates Modified by Zinc Oxide Quantum Dots with Synergistic 3D Lightning Rod Effect, and Electromagnetic and Chemical Enhancements for Highly Sensitive SERS Bacterial Biosensor

Materials Today Nano, Journal Year: 2025, Volume and Issue: unknown, P. 100601 - 100601

Published: Feb. 1, 2025

Language: Английский

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Synthesis, properties, and applications of polyaniline–graphene quantum dot nanocomposites: Comprehensive review

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113460 - 113460

Published: July 1, 2024

Language: Английский

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Metal Oxide Nanoparticles as Efficient Nanocarriers for Targeted Cancer Therapy: Addressing Chemotherapy-Induced Disabilities

Cancers, Journal Year: 2024, Volume and Issue: 16(24), P. 4234 - 4234

Published: Dec. 19, 2024

Cancer remains a predominant global health concern, necessitating effective treatment options. Conventional cancer therapies, particularly chemotherapy, often face constraints such as low selectivity, insufficient solubility, and multidrug resistance (MDR), which diminish effectiveness exacerbate negative effects. Metal oxide nanoparticles (MONPs), iron oxide, zinc copper offer promising solution by enhancing targeted drug delivery, reducing systemic toxicity, mitigating chemotherapy-induced disabilities like neurotoxicity cardiotoxicity. Nanocarriers conjugated with drugs can improve delivery within the body enhance their circulation in bloodstream. Recent advancements MONP synthesis functionalization have further improved stability drug-loading capacity, making them valuable tool treatment. MONPs distinctive physicochemical characteristics, enabling better imaging, encapsulation, medication to cancerous cells. These nanocarriers through focused controlled release, off-target effects addressing resistance. This review aims explore potential of efficient for anticancer drugs, limitations traditional chemotherapy poor specificity, Additionally, discusses recent functionalization, stability, compatibility.

Language: Английский

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Physicochemical and in vitro characterization of Agarose based nanocarriers incorporated with Graphene Quantum Dots/ α-Fe2O3 for targeted drug delivery of Quercetin to liver cancer treatment

Materials Chemistry and Physics, Journal Year: 2024, Volume and Issue: 320, P. 129333 - 129333

Published: May 3, 2024

Language: Английский

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Chitosan-based hydrogels in cancer therapy: Drug and gene delivery, stimuli-responsive carriers, phototherapy and immunotherapy

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137047 - 137047

Published: Nov. 1, 2024

Language: Английский

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Chitosan-grafted folic acid decorated one-dimensional GONS: A biocompatible drug cargo for targeted co-delivery of anticancer agents

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132621 - 132621

Published: May 23, 2024

Language: Английский

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