Heliyon,
Journal Year:
2024,
Volume and Issue:
10(13), P. e33642 - e33642
Published: June 28, 2024
Chitosan
is
a
biocompatible,
non-toxic
and
renewable
natural
basic
polysaccharide
that
can
be
cross-linked
reacted
with
Ce(IV)
to
form
physiologically
active
chitosan-Ce(IV)
complex.
To
investigate
this
novel
complex
its
potential
hydrolyze
phosphate
ester
bonds,
chitosan-cerium
microspheres
resin
(CS-CCMR)
was
prepared
from
chitosan
ceric
ammonium
nitrate
by
reversed-phase
suspension
cross-linking
polymerization.
CS-CCMR
characterized,
ability
disodium
p-nitrobenzene
(PNPP2Na)
organophosphorus
pesticides
investigated,
the
hydrolytic
mechanism
explored.
composed
of
dark
yellow
smooth
surfaces
dense
pores.
It
found
contained
4.507
mg/g
Ce(IV),
indicating
coordination
polymerization
between
successful.
The
presence
in
confirmed
multiple
analytical
methods
it
mediated
nitrogen
atom
amino
group
oxygen
hydroxyl
chitosan.
shown
efficiently
hydrolyzed
bonds
PNPP2Na
five
pesticides.
Hydrolysis
potentially
accomplished
charge
neutralization
nucleophilic
substitution.
parathion
degradation
involves
modification
nitro
give
aminoparathion,
followed
cleavage
P–O
bond
generate
diazinphos.
Consequently,
exhibits
great
efficiency
for
hydrolysis
expected
developed
as
an
agent
reduce
possibility
contamination
fruit
vegetable
drinks
Burns & Trauma,
Journal Year:
2025,
Volume and Issue:
13
Published: Jan. 1, 2025
Abstract
Effective
wound
management
and
treatment
are
crucial
in
clinical
practice,
yet
existing
strategies
often
fall
short
fully
addressing
the
complexities
of
skin
healing.
Recent
advancements
tissue
engineering
have
introduced
innovative
approaches,
particularly
through
use
nanobiomaterials,
to
enhance
healing
process.
In
this
context,
titanium
dioxide
nanoparticles
(TiO2
NPs)
garnered
attention
due
their
excellent
biological
properties,
including
antioxidant,
anti-inflammatory,
antimicrobial
properties.
Furthermore,
these
can
be
modified
therapeutic
benefits.
Scaffolds
dressings
containing
TiO2
NPs
demonstrated
promising
outcomes
accelerating
enhancing
regeneration.
This
review
paper
covers
process,
properties
that
make
them
suitable
for
promoting
healing,
methods
synthesizing
NPs,
scaffolds
application
potential
toxicity
NPs.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: May 20, 2024
Skin
wound
healing
is
a
complex
and
tightly
regulated
process.
The
frequent
occurrence
reoccurrence
of
acute
chronic
wounds
cause
significant
skin
damage
to
patients
impose
socioeconomic
burdens.
Therefore,
there
an
urgent
requirement
promote
interdisciplinary
development
in
the
fields
material
science
medicine
investigate
novel
mechanisms
for
healing.
Cerium
oxide
nanoparticles
(CeO
2
NPs)
are
type
nanomaterials
that
possess
distinct
properties
have
broad
application
prospects.
They
recognized
their
capabilities
enhancing
closure,
minimizing
scarring,
mitigating
inflammation,
exerting
antibacterial
effects,
which
has
led
prominence
care
research.
In
this
paper,
distinctive
physicochemical
CeO
NPs
most
recent
synthesis
approaches
discussed.
It
further
investigates
therapeutic
process
Following
that,
review
critically
examines
previous
studies
focusing
on
effects
Finally,
it
suggests
potential
cerium
as
innovative
nanomaterial
diverse
discusses
its
prospects
future
advancements.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(7), P. 620 - 620
Published: July 3, 2024
This
study
deals
with
the
facile
synthesis
of
a
single-pot
chemical
technique
for
chitosan–curcumin
(CUR)-based
hybrid
nanocomposites
nanostructured
graphene
oxide
(GO)
and
copper
(CuO)
as
antibacterial
cytotoxic
drugs.
The
physicochemical
properties
synthesized
such
CS-GO,
CS-CuO,
CS-CUR-GO,
CS-CUR-GO/CuO
were
confirmed
various
advanced
tools.
Moreover,
in
vitro
drug
release
profile
nanocomposite
exhibited
sustained
controlled
during
different
time
intervals.
Also,
activity
presented
maximum
bactericidal
effect
against
Staphylococcus
aureus
Escherichia
coli
pathogens.
revealed
improved
cytotoxicity
behaviour
cultured
mouse
fibroblast
cells
(L929)
via
cell
adhesion,
DNA
damage,
proliferation.
Thus,
chitosan-based
offer
rich
surface
area,
biocompatibility,
high
oxidative
stress,
bacterial
disruption
functionalities
potential
candidate
applications.
Frontiers in Chemistry,
Journal Year:
2025,
Volume and Issue:
13
Published: April 17, 2025
Titanium
dioxide
nanoparticles
(TiO2NPs)
are
widely
synthesized
chemically
for
industrial
applications.
However,
these
methods
often
have
negative
environmental
impacts,
rendering
them
unsuitable
biomedical
Green
synthesis
approaches
offer
a
promising
alternative
due
to
their
simplicity,
friendliness,
and
cost-effectiveness.
In
this
study,
we
report
the
biosynthesis
of
TiO2NPs
using
Morus
alba
leaf
extract
subsequent
incorporation
into
gellan
gum
(GG)
biopolymer
create
hydrogel.
The
physicochemical
properties
biosynthesized
TiO2NP@GG
hydrogel
were
characterized
Fourier-transform
infrared
spectroscopy
(FTIR),
X-ray
diffraction
(XRD),
scanning
electron
microscopy
(SEM),
energy-dispersive
(EDS),
photoelectron
(XPS).
Furthermore,
bioactivity
materials
was
investigated
through
antibacterial
assays
against
Staphylococcus
aureus
Escherichia
coli,
as
well
in
vitro
wound
healing
studies
3T3
fibroblast
scratch
assay.
XRD
analysis
confirmed
successful
formation
anatase
phase
TiO2.
SEM
images
revealed
presence
irregular
rod-shaped
TiO2
nanoparticles,
with
EDS
confirming
composition
oxygen
titanium.
particle
size
determined
be
80-90
nm,
exhibited
homogeneous
distribution
throughout
network.
displayed
significant
activity
both
S.
E.
coli.
assay
on
cells
seeded
onto
demonstrated
high
cell
survival
rate
enhanced
migration,
suggesting
potential
applications
dressing
material.
