International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138387 - 138387
Published: Dec. 1, 2024
Language: Английский
Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 142785 - 142785
Published: Jan. 1, 2025
Language: Английский
Citations
2
Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(33), P. 8007 - 8032
Published: Jan. 1, 2024
Inflammatory skin diseases, such as psoriasis and atopic dermatitis, pose significant health challenges due to their long-lasting nature, potential for serious complications, risks, which requires treatments that are both effective exhibit minimal side effects. Hydrogels offer an innovative solution biocompatibility, tunability, controlled drug delivery capabilities, enhanced treatment adherence minimized effects risk. This review explores the mechanisms guide design of hydrogel therapeutic platforms from multiple perspectives, focusing on components hydrogels, adjustable physical chemical properties, interactions with cells drugs underscore clinical potential. We also examine various agents dermatitis can be integrated into including traditional drugs, novel compounds targeting oxidative stress, small molecule biologics, emerging therapies, offering insights advantages. Additionally, we trial data evaluate effectiveness safety hydrogel-based in managing under complex disease conditions. Lastly, discuss current future opportunities therapeutics treating improving barrier penetration developing multifunctional highlight enhance long-term stability.
Language: Английский
Citations
16
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 494, P. 153250 - 153250
Published: June 17, 2024
Graphene oxide (GO) membranes hold promise for selective CO2 adsorption over N2 due to their carboxyl groups, making them attractive flue gas capture. However, challenges such as limited content, flexible nanosheets, and dense layer stacking hinder N2/CO2 selectivity, pressure resistance, permeability. In this study, we introduce a specific sub-nanometer framework structure within GO by in-situ growing ZIF-8 nanocrystals. This novel approach, achieved through simultaneous infiltration of zinc nitrate 2-methylimidazole precursors on both sides the membrane, enhances capture resistance capabilities resulting ZIF-8@GO composite membranes. Additionally, incorporation carboxylated wrinkled graphene (WG) ethylenediamine (EDA) cross-linking agent molecules improves capability introduces reinforced porous structures enhance Experimental results demonstrate remarkable permeability, prepared ZIF-8@EDA-GO/WG Under 0.2 MPa, permeability reaches 1850 GPU, with theoretical selectivity single separation factors mixed gases 18.3 32.3, respectively, surpassing conventional (3 1.1, 1.2). Even under elevated air conditions (1.2 MPa), maintain 13.4. Our membrane design strategy not only advances development functional but also contributes mitigating emissions from gas, thereby combating global warming.
Language: Английский
Citations
10
Nutraceuticals, Journal Year: 2024, Volume and Issue: 4(4), P. 522 - 561
Published: Oct. 11, 2024
Inflammation and thrombosis are implicated in several non-communicable chronic disorders, including cardiovascular diseases, diabetes, renal neurodegenerative skin especially cancer. Natural bioactives phytochemicals like phenolic compounds have been proposed to reduce the inflammatory burden with health benefits against these disorders. Vanillin is a compound found seeds of various species vanilla plants. It has known since ancient times for its aromatic soothing properties; however, recent outcomes outlined other pleiotropic actions this bioactive compound. Within article, potent anti-inflammatory activities vanillin derivatives thoroughly reviewed, emphasis on their anti-cancer, anti-infective, wound-healing, neuroprotective health-promoting properties. The mechanisms action(s), along from vitro vivo studies clinical trials, vanillin-based each specific types cancer, also outlined. Limitations future perspectives use solely as ingredients, ingredients functional products—such foods, supplements, nutraceuticals, or even cosmetics drugs—and adjuvant therapies discussed.
Language: Английский
Citations
10
European Polymer Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113797 - 113797
Published: Feb. 1, 2025
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140869 - 140869
Published: Feb. 12, 2025
Language: Английский
Citations
0
Bioengineering, Journal Year: 2025, Volume and Issue: 12(5), P. 439 - 439
Published: April 23, 2025
Wound infections remain a significant clinical challenge, impeding healing and causing deterioration. Recently, multifunctional hydrogel dressings have gained interest as an effective treatment to treat efficiently enhance wound recovery. The present research is focused on the development of composite hydrogels comprising chitosan (CS), polyvinyl alcohol (PVA), gelatin (GEL) licorice extract (LE), using freeze gelation technique. resulting CS/PVA/GEL incorporating LE were characterized by FTIR, XRD SEM. FTIR analysis confirmed presence specific functional groups within molecules. exhibited amorphous nature hydrogels. SEM revealed that increasing CS ratio in created more porous structure with smaller pore size. All demonstrated oxygen permeability, which crucial for process. Among synthesized hydrogels, MM-2 containing PVA (20 mL) (4 superior performance water retention capacity 440% moisture content 91%. This exceptional result can be attributed higher proportion material’s structure, enhances its hydrophilic properties. showed good antibacterial potential against three selected strains bacteria including Bacillus subtilis (B. subtilis), Staphylococcus aureus (S. aureus) Escherichia coli (E. coli). hydrogels’ cytotoxicity levels assessed through hemolysis assay results all non-toxic. hydrolytic breakdown interconnected components slow degradation, making them appropriate long-term treatment. Specifically, MM-4 74% degradation rate displayed 75% antioxidant activity, indicating effectiveness chronic applications. These characteristics CS/PVA/GEL/LE-derived suggest their use promising candidate care
Language: Английский
Citations
0
Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 342, P. 103527 - 103527
Published: April 25, 2025
Language: Английский
Citations
0
Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 137161 - 137161
Published: May 1, 2025
Language: Английский
Citations
0
Journal of Applied Biomaterials & Functional Materials, Journal Year: 2024, Volume and Issue: 22
Published: Jan. 1, 2024
Vanillin loaded-physically crosslinked hydrogel membranes made of PVA/chitosan/itaconic acid (PVA-CS-IA) were prepared using freezing-thawing (F-T) cycle method. To ensure the entanglement PVA-CS-IA chains, three F-T cycles repeated. The polymeric chains entanglements confirmed and characterized by different instrumental characterizations. Physicochemical properties for example, swelling ratio, mechanical characteristics, gel fraction percentage (GF%), hydrolytic degradation, thermal stability membrane discussed in detail. findings showed that degradation enhanced with increasing CS-IA contents composition; however, GF% gradually declined content. Additionally, cell viability test HFB-4 line antimicrobial activity against
Language: Английский
Citations
3