BMC Plant Biology,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 14, 2025
Arctium
lappa
L.
is
a
medicinal
edible
homologous
plant,
commonly
known
as
burdock
or
bardana,
which
belongs
to
the
Asteraceae
family
and
abundant
all
over
world.
Genetic
diversity
assessment
essential
for
A.
germplasm
resource
conservation
breeding.
The
techniques
include
morphological,
biochemical,
DNA
marker
analysis.
However,
limited
number
of
available
markers
insufficient
conduct
related
genetic
studies.
In
this
study,
we
conducted
RNA
sequencing
cultivar
'Yanagikawa
Ideal'
developed
SSR
characterize
population
structure
56
accessions
8
wild
relative
accessions.
A
total
4,851
simple
sequence
repeats
(SSRs)
loci
were
identified.
proportions
mono-,
di-
tri-nucleotide
repeat
motifs
30.40%,
21.50%
33.10%,
respectively.
We
verified
reliability
28
core
primer
pairs
through
electronic
polymerase
chain
reaction
(ePCR)
PCR
amplification
process.
polymorphism
information
content
(PIC)
values
ranged
from
0.246
0.848,
with
14
primers
displaying
high
(PIC
>
0.5).
showed
100%
mobility
in
tomentosum
Miller
96.43%
Synurus
deltoides
(Aiton)
Nakai,
indicating
their
versatility.
average
Shannon
index
(I)
was
1.231,
observed
heterozygosity
(Ho)
0.132,
expected
(He)
0.564.
64
divided
into
three
clusters
at
distance
0.558.
AMOVA
analysis
shows
83%
variation
within
populations
17%
among
populations,
highlighting
implications
breeding
strategies.
Our
study
provides
newly
high-quality
enhance
programs
lappa,
well
support
comparative
genomics
cross-species
strategies
species.
Artificial Cells Nanomedicine and Biotechnology,
Journal Year:
2024,
Volume and Issue:
52(1), P. 564 - 586
Published: Dec. 5, 2024
Cancer
has
a
high
rate
of
incidence
and
mortality
throughout
the
world.
Although
several
conventional
approaches
have
been
developed
for
treatment
cancer,
such
as
surgery,
chemotherapy,
radiotherapy
thermal
therapy,
they
remarkable
disadvantages
which
result
in
inefficient
cancer.
For
example,
immunogenicity,
prolonged
treatment,
non-specificity,
metastasis
cost
are
considered
major
drawbacks
chemotherapy.
Therefore,
there
is
fundamental
requirement
development
breakthrough
technologies
cancer
suppression.
Polysaccharide-based
drug
delivery
systems
(DDSs)
most
reliable
carriers
therapy.
Polysaccharides,
kind
practical
biomaterials,
divided
into
types,
including
chitosan,
alginates,
dextran,
hyaluronic
acid,
cyclodextrin,
pectin,
etc.
Polysaccharides
extracted
from
different
natural
resources
(like
herbal,
marine,
microorganisms,
etc.).
The
potential
features
polysaccharides
made
them
candidates
therapeutics
to
sites;
simple
purification,
ease
modification
functionalization,
hydrophilicity,
serum
stability,
appropriate
loading
capacity,
biocompatibility,
bioavailability,
biodegradability
stimuli-responsive
sustained
release
manner
considerable
aspects
these
biopolymers.
This
review
highlights
applications
polysaccharides-based
DDSs
pharmaceutical
science
Ukrainian Journal of Military Medicine,
Journal Year:
2025,
Volume and Issue:
6(1), P. 170 - 178
Published: March 31, 2025
Purpose.
Development
of
the
composition
plant
collection
“Opornofit”
and
technology
obtaining
a
liquid
extract
on
its
basis
for
prevention
treatment
diseases
musculoskeletal
system,
with
determination
quality
indicators
stability
during
their
storage.
Materials
methods.
Plant
raw
materials
from
it
were
harvested
in
Vinnytsia
Kharkiv
regions.
The
numerical
parameters
determined
according
to
methods
State
Pharmacopoeia
Ukraine
2.0.
Results.
A
screening
range
medicinal
materials,
which
form
mono-
polycomponent
collections
are
used
phytotherapy
was
carried
out
most
promising
types
selected
creating
“Opornofit”:
Arctium
root
(Arctium
lappa
L.,
minus
(Hill)
Bernh.,
tomentosum
Mill.),
Rose
(Rosa
majalis
Herrm.,
Rosa
canina
L.),
rhizomes
roots
Sanguisorba
officinalis
Rumex
confertus
Willd.,
herb
Bidens
tripartita
L.
an
equal
ratio
components
collection.
Taking
into
account
conditions
military
service
frequent
lack
preparing
decoction
collection,
we
developed
based
components.
For
extract,
storage
year
studied.
Conclusions.
herbal
system
have
been
developed,
original
predicted
anti-inflammatory,
uricosuric,
detoxifying,
desensitizing,
immunostimulating
effects.
