Mild ultrasound-assisted alkali de-esterification modified pectins: Characterization and structure–activity relationships in immunomodulatory effects DOI Creative Commons
Huan Guo, Li Dong, Bin Miao

et al.

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 112, P. 107215 - 107215

Published: Dec. 31, 2024

Language: Английский

Development of pectin/chitosan-based electrospun biomimetic nanofiber membranes loaded with dihydromyricetin inclusion complexes for wound healing application DOI
Huan Guo,

Wenyi Ran,

Xuchu Jin

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134526 - 134526

Published: Aug. 5, 2024

Language: Английский

Citations

15

Development of apple pectin/soy protein isolate-based edible films containing punicalagin for strawberry preservation DOI
Huan Guo,

Anning Li,

Gangqiang Huang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 133111 - 133111

Published: June 12, 2024

Language: Английский

Citations

11

Unraveling the web of defense: the crucial role of polysaccharides in immunity DOI Creative Commons

Yu Shen,

Hongbo Zhao, Xuefeng Wang

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 25, 2024

The great potential of polysaccharides in immunological regulation has recently been highlighted pharmacological and clinical studies. Polysaccharides can trigger immunostimulatory responses through molecular identification, intra- intercellular communication via direct or indirect interactions with the immune system. Various their derivative compounds interacts at cellular level to boost system, including arabinogalactans, fucoidans, mannans, xylans, galactans, hyaluronans, fructans, pectin etc. These natural are derived from various plants, animals microbes. A unique structural diversity identified polysaccharides, while monosaccharides glucosidic bonds mainly confer diverse biological activities. improve antioxidant capacity, reduce production pro-inflammatory mediators, strengthen intestinal barrier, influence composition microbial populations promote synthesis short-chain fatty acids. also known excessive inflammatory responses. It is crucial develop polysaccharide-based immunomodulators that could be used prevent treat certain diseases. This review highlights features, immunomodulatory properties, underlying mechanisms naturally occurring activities related effects by elucidating a complex relationship between immunity. In addition, future these molecules as components transform pharmaceutical applications will highlighted.

Language: Английский

Citations

7

Combination of lipopolysaccharide and polygalacturonic acid exerts antitumor activity and augments anti-PD-L1 immunotherapy DOI
Jie Song, Jiaxin Li, Anping Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 136390 - 136390

Published: Oct. 9, 2024

Language: Английский

Citations

1

Structured Fruit Cube Snack of BRS Vitoria Grape with Gala Apple: Phenolic Composition and Sensory Attributes DOI Creative Commons
Yara Paula Nishiyama-Hortense, Carolina Olivati, Victoria Diniz Shimizu-Marin

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(21), P. 5205 - 5205

Published: Nov. 4, 2024

This study developed a structured fruit cube (FC) snack using only natural ingredients, specifically red grape and apple, without hydrocolloids sucrose. After development, physicochemical characterization analysis of phenolic compounds (PCs), including anthocyanins, flavonols, hydroxycinnamic acid derivatives, HPLC-DAD-ESI-MS/MS, were conducted. Sensory quality was also assessed through an acceptance sensory profile the rate-all-that-apply methodology. The results showed that FC had characteristics similar to other fruits use hydrocolloids. Additionally, they presented complex composition PCs, predominantly anthocyanins derived from malvidin (tri-substituted methoxylated anthocyanins), notably cumarylated ones. Flavonols comprised 3-glucoside series myricetin, quercetin, laricitrin, kaempferol, isorhamnetin, syringetin; 3-galactoside myricetin quercetin; 3-glucuronic quercitin, along with rutin. presence caftaric acid, coutaric fertaric p-coumaroyl-glucose detected, alongside caffeic acid-O-glucoside 1, 2, chlorogenic 4-O-p-coumaroylquinic dicaffeoylquinic acid. In conclusion, selection ingredients technologically suitable for obtaining FC. Despite conventional drying at 60 °C, product notable concentrations PCs achieved great acceptance.

Language: Английский

Citations

1

Mild ultrasound-assisted alkali de-esterification modified pectins: Characterization and structure–activity relationships in immunomodulatory effects DOI Creative Commons
Huan Guo, Li Dong, Bin Miao

et al.

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 112, P. 107215 - 107215

Published: Dec. 31, 2024

Language: Английский

Citations

1