International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136777 - 136777
Published: Oct. 21, 2024
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 134788 - 134788
Published: Aug. 20, 2024
The long-term use of antibiotics can cause drug resistance. Natural polysaccharides are a novel means treating bacterial infections, and the development utilization litchi pericarp polysaccharide (LPPs) as bacteriostatic active substance offer new research direction for high-value by-products. This study revealed that LPPs inhibited Staphylococcus aureus more than Escherichia coli, Listeria monocytogenes, Salmonella typhimurium, with minimum inhibitory concentrations 145, 205, 325, 445 μg/mL, respectively. activity was insignificant Bacillus subtilis at 505 μg/mL. assessment antibacterial mechanisms influenced growth, conductivity, protein, nucleic acid, reducing sugar, respiratory chain dehydrogenase activity, lipid peroxidation, intracellular adenosine triphosphate, extracellular alkaline phosphatase levels S. aureus. Of note, could modify cell wall integrity membrane permeability aureus, resulting in leakage large small molecules, inhibition cellular metabolism, oxidative losses. These processes exhibited an effect made bacterium nonfunctional, thereby affecting its growth metabolism or causing death. findings provide support insights into potential application natural antimicrobial agent.
Language: Английский
Citations
37
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 136472 - 136472
Published: Oct. 15, 2024
Language: Английский
Citations
23
Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11
Published: Jan. 6, 2025
In this study, Chinese yam polysaccharides (CYPs) were fermented using Lactobacillus plantarum M616, and changes in the chemical composition, structure, anti-inflammatory activity of CYPs before after fermentation investigated. The carbohydrate content L. M616-fermented CYP (CYP-LP) increased from 71.03% ± 2.75 to 76.28% 2.37%, whereas protein polyphenol almost unaffected compared with those unfermented (CYP-NF). monosaccharide composition CYP-NF included rhamnose, arabinose, galactose, glucose, mannose a molar ratio 0.493:0.6695:0.9738:0.7655:12.4365. CYP-LP had same monosaccharides as CYP-NF, but was 0.3237:0.3457:0.8278:2.5541:10.4995. Meanwhile, molecular weight polydispersity CYP-LP, respectively, 124.774 kDa 6.58 (CYP-NF) 376.628 17.928, indicating low homogeneity. vitro antioxidant analysis showed that M616 varying effects on against DPPH, ABTS, hydroxyl, superoxide radicals. However, superior is more effective regulating dismutase, catalase, glutathione peroxidase, malondialdehyde, nitric oxide, tumor necrosis factor-α, interleukin-1β, interleukin-6 release lipopolysaccharide-induced RAW 264.7 macrophages. This study suggested potential ingredient drugs functional food.
Language: Английский
Citations
3
Food Bioscience, Journal Year: 2024, Volume and Issue: 61, P. 104648 - 104648
Published: June 27, 2024
Language: Английский
Citations
13
Innovative Food Science & Emerging Technologies, Journal Year: 2024, Volume and Issue: 98, P. 103863 - 103863
Published: Nov. 4, 2024
Language: Английский
Citations
11
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140052 - 140052
Published: Jan. 1, 2025
Language: Английский
Citations
1
Foods, Journal Year: 2025, Volume and Issue: 14(4), P. 564 - 564
Published: Feb. 8, 2025
In this study, Chinese yam polysaccharide (CYP) was fermented by Saccharomyces cerevisiae CICC 32883, and its structural features antioxidant activities before after fermentation were analyzed. S. 32883-fermented CYP (CYP-SC) had higher carbohydrate content lower protein than the nonfermented (CYP-NF). The monosaccharide composition of CYP-SC unaffected, but proportion changed. Compared with CYP-NF's molecular weight polydispersity 124.774 kDa 6.58, respectively, those reduced to 20.384 3.379. Antioxidant results showed that better effects CYP-NF in scavenging DPPH, ABTS, hydroxyl, superoxide radicals. Moreover, enhancing oxidation capacity protecting HepG2 cells CYP-NF. Furthermore, on alleviating repairing H2O2-damaged are superior This work offers a green efficient method for activity dietary plant polysaccharides.
Language: Английский
Citations
1
Fitoterapia, Journal Year: 2025, Volume and Issue: 181, P. 106379 - 106379
Published: Jan. 6, 2025
Language: Английский
Citations
0
Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: 9, P. 100699 - 100699
Published: Feb. 6, 2025
Language: Английский
Citations
0
Preparative Biochemistry & Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10
Published: Feb. 18, 2025
Due to the restricts of treatment methods and high costs, waste tobacco materials are usually discarded, which leads resources environmental pollution. Present work used leaves as carbon source produce polysaccharide (CGP-TL) by Chaetomium globosum CGMCC 6882 via submerged fermentation. CGP-TL yield was 1.62 ± 0.35 g/L, contents carbohydrate protein in were 91.73% 6.49% 5.51% 0.84%. Structural characterization showed composed rhamnose, arabinose, galactose, glucose, mannose xylose a molar ratio 9.9688: 6.8482: 19.6045: 29.4448: 0.8033: 0.5874. Meanwhile, its weight-average molecular weight, number-average weight polydispersity 286.035 kDa, 118.146 kDa 2.421, respectively. In vitro antioxidant analysis scavenged DPPH, ABTS, hydroxyl superoxide radicals positively correlated concentration, corresponding scavenging effects at 2.5 mg/mL 75.53% 1.89%, 96.24% 2.32%, 52.91% 2.28% 65.26% 2.47%. Furthermore, not only improved antioxidative status RAW 264.7 cells, but also exerted oxidative repairing on H2O2-damaged cells increasing levels SOD, CAT GSH-Px, reducing MDA level. Overall, this will provide references for green efficient utilization cellulose resources.
Language: Английский
Citations
0