Various steaming durations alter digestion, absorption, and fermentation by human gut microbiota outcomes of Polygonatum cyrtonema Hua polysaccharides DOI Creative Commons
Weijing Wu,

Yanling Wang,

Ping Yi

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 19, 2024

Introduction Different steaming durations dramatically alter the structure of Polygonatum cyrtonema polysaccharides (PCPs). This study aimed to compare characteristics digestion, absorption, and fermentation by gut microbiota across four representative PCPs from different (0, 4, 8, 12 h), each with unique molecular weights monosaccharide profiles. Methods Chemical composition was analyzed. Digestibility evaluated using an in vitro saliva-gastrointestinal digestion model. Absorption were assessed a Caco-2 monolayer model, impacts on short chain fatty acid (SCFA) levels analyzed human microbiota. Results Longer altered chemical profiles PCPs, reducing carbohydrate content (84.87–49.58%) increasing uronic (13.99–19.61%), protein (1.07–5.43%), polyphenols (0.05–2.75%). Four unaffected saliva but showed enhanced gastrointestinal digestibility, sugar rising 4.06% (P0) 38.5% (P12). The varying absorption characteristics, P0 having highest permeability coefficient value 9.59 × 10 −8 cm/s. However, all exhibited poor permeability, favoring fermentation. elevated SCFA production, declined progressively longer durations. All significantly increased abundance Bacteroidota, Firmicutes, Actinobacteriota, making them dominant bacterial phyla. Additionally, Bifidobacterium, Prevotella , Faecalibacterium compared control group, which, along Bacteroides became Increasing duration led reduction levels, raw rhizomes showing relative at 24.90%. moderately steamed (4 h) significant rise (7.73%) among PCPs. P8 P12, derived extensively (≥8 similar compositions, higher abundances (20.23–20.30%) Bifidobacterium (21.05–21.51%) P4. Discussion research highlights importance adjusting maximize probiotic potential P. polysaccharides, enhancing their effectiveness modulating levels.

Language: Английский

Structural characteristics and intestinal flora metabolism mediated immunoregulatory effects of Lactarius deliciosus polysaccharide DOI
Xiaodan Dong,

Sujun Sun,

Xinkun Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 135063 - 135063

Published: Aug. 24, 2024

Language: Английский

Citations

22
Evolutionary research trends of polysaccharides from Polygonatum genus: A comprehensive review of its isolation, structure, health benefits, and applications DOI
Yanjun Yang, Yufei Yang, Weilin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141566 - 141566

Published: Feb. 1, 2025

Language: Английский

Citations

1
Physicochemical characterization and protective effects of raw and nine-steamed Polygonatum cyrtonema polysaccharides on cyclophosphamide-induced immunosuppression in mice DOI
Weiguang Luo,

Xiuwei Li,

Chenxi Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141911 - 141911

Published: March 1, 2025

Language: Английский

Citations

1
Fabrication of synbiotic carbohydrate polymer-based microcapsules: Effect of prebiotics on probiotic viability during freeze-drying, gastrointestinal transit and storage DOI
Korlid Thinkohkaew, Veasarach Jonjaroen, Nuttawee Niamsiri

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123582 - 123582

Published: April 1, 2025

Language: Английский

Citations

0
Non-targeted metabolomics-mediated elucidation of metabolite changes in Polygonatum kingianum during traditional steaming with black beans DOI Creative Commons

Haiyan Zhu,

Zhikun Pei, Lei Zhang

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 11, 2025

Polygonatum is a traditional medicinal and edible plant often prepared by steaming it with ingredients like yellow rice wine black beans. However, the metabolic changes in kingianum (PK) during method beans have not been previously reported. This study aims to explore how addition of degree affect quality PK. quantified polysaccharides, reducing sugars, saponins, flavonoids PK subjected varied cycles, while also integrating color measurement, sensory evaluation, non-targeted metabolomics analysis. rich lipids, amino acids, flavonoids, organic acids. Notably, we observed production significant accumulation daidzein daidzin (two primary active compounds derived from beans) as well triterpenoid saponins (including Sandosaponin A, Soyasaponin II-III, V, Pisumsaponin I-II) steamed (p < 0.05). After three multiple bioactive levels peaked or stabilized, which was consistent (score: 94/100). Compared raw PK, P3 stage exhibited increases total 21.29, 35.02, 49.13, 44.76%, respectively 0.05), sugars showed remarkable increase 160.94-fold 0.01), polysaccharides decreased significantly 43.33% 0.01). provides first evidence that can synergistically diversity isoflavones optimal achieved after rounds steaming. These findings validate scientific efficacy processing method. Our results advocate for continued use bean enhance nutritional health-promoting value providing template innovation herbal techniques based on auxiliary ingredients.

Language: Английский

Citations

0
Structural characterization and antioxidant activity in aging mice of a homogenous polysaccharide isolated from Ecklonia kurome DOI
Qiaoying Song,

Ziqing Liu,

Zhao Baoyi

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1318, P. 139111 - 139111

Published: June 24, 2024

Language: Английский

Citations

3
Various steaming durations alter digestion, absorption, and fermentation by human gut microbiota outcomes of Polygonatum cyrtonema Hua polysaccharides DOI Creative Commons
Weijing Wu,

Yanling Wang,

Ping Yi

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 19, 2024

Introduction Different steaming durations dramatically alter the structure of Polygonatum cyrtonema polysaccharides (PCPs). This study aimed to compare characteristics digestion, absorption, and fermentation by gut microbiota across four representative PCPs from different (0, 4, 8, 12 h), each with unique molecular weights monosaccharide profiles. Methods Chemical composition was analyzed. Digestibility evaluated using an in vitro saliva-gastrointestinal digestion model. Absorption were assessed a Caco-2 monolayer model, impacts on short chain fatty acid (SCFA) levels analyzed human microbiota. Results Longer altered chemical profiles PCPs, reducing carbohydrate content (84.87–49.58%) increasing uronic (13.99–19.61%), protein (1.07–5.43%), polyphenols (0.05–2.75%). Four unaffected saliva but showed enhanced gastrointestinal digestibility, sugar rising 4.06% (P0) 38.5% (P12). The varying absorption characteristics, P0 having highest permeability coefficient value 9.59 × 10 −8 cm/s. However, all exhibited poor permeability, favoring fermentation. elevated SCFA production, declined progressively longer durations. All significantly increased abundance Bacteroidota, Firmicutes, Actinobacteriota, making them dominant bacterial phyla. Additionally, Bifidobacterium, Prevotella , Faecalibacterium compared control group, which, along Bacteroides became Increasing duration led reduction levels, raw rhizomes showing relative at 24.90%. moderately steamed (4 h) significant rise (7.73%) among PCPs. P8 P12, derived extensively (≥8 similar compositions, higher abundances (20.23–20.30%) Bifidobacterium (21.05–21.51%) P4. Discussion research highlights importance adjusting maximize probiotic potential P. polysaccharides, enhancing their effectiveness modulating levels.

Language: Английский

Citations

2