Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101322 - 101322
Published: Nov. 1, 2024
Language: Английский
Biomolecules, Journal Year: 2024, Volume and Issue: 14(7), P. 789 - 789
Published: July 3, 2024
Alginate is a natural polymer with good biocompatible properties and potential polymeric material for the sustainable development replacement of petroleum derivatives. However, non-spinnability pure alginate solutions has hindered expansion applications. With continuous electrospinning technology, synthetic polymers, such as PEO PVA, are used co-spinning agents to increase spinnability alginate. Moreover, coaxial, parallel Janus, tertiary other diverse novel electrospun fiber structures prepared by multi-fluid have found new breakthrough problem poor spinning polymers. Meanwhile, effectively achieve multiple release modes drugs. The powerful combination electrostatic widely in many biomedical fields, tissue engineering, regenerative bioscaffolds, drug delivery, research fever continues climb. This particularly true controlled delivery aspect review provides brief overview alginate, introduces advances spinning, highlights progress alginate-based nanofibers achieving various modes, pulsed release, sustained biphasic responsive targeted release.
Language: Английский
Citations
48
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(17), P. 9524 - 9524
Published: Sept. 1, 2024
Core–shell nanostructures are powerful platforms for the development of novel nanoscale drug delivery systems with sustained release profiles. Coaxial electrospinning is facile and convenient creating medicated core–shell elaborate designs which sustained-release behaviors molecules can be intentionally adjusted. With resveratrol (RES) as a model poorly water-soluble cellulose acetate (CA) PVP polymeric carriers, brand-new electrospun nanostructure was fabricated in this study. The guest RES host CA were designed to have reverse gradient distribution within nanostructures. Scanning electron microscope transmission evaluations verified that these nanofibers had linear morphologies, without beads or spindles, an obvious double-chamber structure. X-ray diffraction patterns Fourier transform infrared spectroscopic results indicated involved components highly compatible presented amorphous molecular state. In vitro dissolution tests new structures able prevent initial burst release, extend continuous-release time period, reduce negative tailing-off effect, thus ensuring better profile than traditional blended drug-loaded nanofibers. mechanism underlying influence structure RES/CA on proposed. Based proof-of-concept demonstration, series advanced functional nanomaterials similarly developed based distributions multi-chamber
Language: Английский
Citations
24
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 135753 - 135753
Published: Oct. 17, 2024
Language: Английский
Citations
24
International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 4677 - 4703
Published: April 1, 2025
Despite relentless effort to study glioma treatment, the prognosis for patients remains poor. The main obstacles include high rate of recurrence and difficulty passing blood-brain barrier (BBB) therapeutic drugs. Nanomaterials owing their special physicochemical properties have been used in a wide range fields thus far. nanodrug delivery system (NDDS) with ability crossing BBB, targeting site, maintaining drug stability controlling release, has significantly enhanced anti-tumor effect, improving patients. Aligned nanofibers (NFs) are ideal materials establish vitro models microenvironment (GME), enabling exploration mechanism cell migration invasion discover novel targets. Moreover, NFs now widely applications such as radiotherapy, phototherapy, thermotherapy immunotherapy. absolute dominance anti-glioma applications, there still some problems further optimization NDDS, impact interactions between protein corona (PC) on therapy. This paper will shed light latest systems mimicking tumor (TME), discuss how optimize NDDS eliminate or utilize nanomedicine-PC interactions.
Language: Английский
Citations
0
Heliyon, Journal Year: 2024, Volume and Issue: 10(23), P. e40460 - e40460
Published: Nov. 15, 2024
Cold plasma (CP) is an emerging technology employed to safeguard highly perishable food items, particularly aquatic products such as shrimp. Due its significant amount of moisture, superior protein composition that contains important amino acids, and unsaturated fatty acid content, shrimp are susceptible microbial deterioration overall alterations in their physical chemical characteristics. Such spoilage not only diminishes the nutritional value but also has potential generate harmful substances, rendering it unsuitable for consumption. Recent observations have indicated a growing market demand maintains quality prolonged shelf life. Furthermore, there emphasis on production items undergo minimal processing or nonthermal preservation methods. Extensive documentation exists regarding efficacy CP eliminating microorganisms from without inducing resistance activating enzymes contribute spoilage. Therefore, can be mentioned slight interference preserve quality. This chapter primarily explores principles methods technology, well impact melanosis, physicochemical changes, sensory properties,
Language: Английский
Citations
1
ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 30, 2024
Language: Английский
Citations
1
Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101322 - 101322
Published: Nov. 1, 2024
Language: Английский
Citations
0