Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 2, 2024
Language: Английский
Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 2, 2024
Language: Английский
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 353, P. 123276 - 123276
Published: Jan. 16, 2025
Language: Английский
Citations
3International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141742 - 141742
Published: March 1, 2025
Language: Английский
Citations
0Published: Oct. 23, 2024
Various methods have been studied to speed up the wound healing process. Promoting rapid development of blood vessels, also known as angiogenesis, is essential this significantly accelerates skin regeneration. This study identified a polysaccharide from red alga Osmundea pinnatifida (PSOP) that promotes angiogenesis and healing. Firstly, we analyzed structural characteristics PSOP using various techniques such UV-visible spectrum, Fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (X-RD), scanning electron microscopy (SEM), high-performance liquid chromatography coupled refractive index detector (HPLC-RID). We evaluated antioxidant properties in vitro tests for DPPH free radical scavenging capacity, iron reduction capacity (RPA), total (TAC). Additionally, observed significant increase new vessel formation chorioallantoic membrane model (CAM assay) fertilized hen egg, indicating pro-angiogenic effect PSOP. Furthermore, tested wound-healing potential hydrogel vivo excision wounds Wistar rat model. The results showed notable acceleration closure an improvement tissue regeneration collagen deposition quality within 11 days, strong activity Our computational suggested units bind cyclooxygenase 2 (COX-2) vascular endothelial growth factor (VEGF) with acceptable affinities interactions, which might explain beneficial seen experimental assays. findings support treatment due its potential.
Language: Английский
Citations
1Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 5, 2024
Language: Английский
Citations
1Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 2, 2024
Language: Английский
Citations
0