Acanthopanax seeds polysaccharide improve alcoholic fatty liver disease through the gut-liver axis

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140200 - 140200

Published: Jan. 1, 2025

Language: Английский

---

Therapeutic Effects and Mechanisms of Alcohol Extracts from Polygala fallax Hemsl on Endometriosis in Rats

Archives of Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown, P. 110393 - 110393

Published: March 1, 2025

Language: Английский

---

Mechanism of polyphenol-pea starch complexes on reducing fat accumulation in Caenorhabditis elegans

Food Research International, Journal Year: 2025, Volume and Issue: unknown, P. 116308 - 116308

Published: March 1, 2025

Language: Английский

---

Recent advances in the role of polysaccharides in liver diseases: a review

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: March 27, 2025

Liver diseases are a serious health problem worldwide, especially with sustained increase in the burden of it every year. However, drugs commonly used patients have limited efficacy and adverse reactions associated long-term use. Therefore, is urgent to find effective safe alternatives. Polysaccharides currently considered promising alternatives traditional because their extensive activity low toxicity. This review investigated studies on hepatoprotective polysaccharides over past 6 years, detailing effects, potential mechanisms, drug carrier applications. These findings suggest that prominent preventive therapeutic effects various liver such as drug-induced injury, alcoholic disease, hepatitis B, non-alcoholic fatty fibrosis, hepatocellular carcinoma. Its mechanism includes multiple aspects metabolic regulation, reduction oxidative stress inflammation, regulation gut microbiota. Furthermore, owing good physicochemical properties, been applied delivery systems for chemotherapy small molecule drugs. further research essential bioavailability, structure-activity relationship, more clinical evidence polysaccharides. Continued exploration will provide tremendous treatment diseases.

Language: Английский

---

Curcumol ameliorates alcohol and high-fat diet-induced fatty liver disease via modulation of the Ceruloplasmin/iron overload/mtDNA signaling pathway

The Journal of Nutritional Biochemistry, Journal Year: 2024, Volume and Issue: unknown, P. 109807 - 109807

Published: Nov. 1, 2024

Language: Английский

---

Impact of Imperata Cylindrica polysaccharide on liver lipid metabolism disorders caused by hyperuricemia

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137592 - 137592

Published: Nov. 16, 2024

Language: Английский

---