AAPS PharmSciTech, Journal Year: 2023, Volume and Issue: 24(5)
Published: May 24, 2023
Language: Английский
Reactive and Functional Polymers, Journal Year: 2022, Volume and Issue: 179, P. 105374 - 105374
Published: Aug. 10, 2022
4D bioprinting is the next-generation additive manufacturing-based fabrication platform employed to construct intricate, adaptive, and dynamic soft hard tissue structures as well biomedical devices. It achieved by using stimuli-responsive materials, especially shape memory polymers (SMPs) hydrogels, which possess desirable biomechanical characteristics. In last few years, numerous efforts have been made printing community develop novel polymeric materials considering their perspective. This review presents an up-to-date overview of technology incorporating functionalities biomaterials focused approach towards different engineering regenerative medicine (TERM) applications. includes bone, cardiac, neural, cartilage, drug delivery systems, other high-value also addresses current limitations challenges in provide a basis for foreseeable advancements TERM applications that could be helpful successful utilization clinical settings.
Language: Английский
Citations
142
Advanced Science, Journal Year: 2024, Volume and Issue: 11(17)
Published: Feb. 11, 2024
Abstract Solar desalination using hydrogel evaporators is an eco‐friendly, highly efficient means with natural sunlight for sustainable freshwater production. However, it remains challenging to develop a cost‐effective and scalable method prepare salt‐resistant stable desalination. Here, inspired by tree transpiration hierarchical porous structure, 3D‐printed bionic evaporator (3DP‐BHE) designed long‐term solar Commercialized activated carbon (AC) introduced into biomass starch skeleton as light absorber build 3DP‐BHE in fashion ($10.14 m −2 of total materials cost). The leaf layer 94.01% absorption timely vapor diffusion. trunk 3D printed bimodal structure water transfer, thermal isolation, salt ions convection With the unique achieves evaporation rate 2.13 kg h −1 at ≈90.5% energy efficiency under one sun (1 kW ). During 7‐day 10 wt.% brine, steady 1.98 maintained record‐high cost‐effectiveness (195.3 g $ ) manner. This will open significant opportunities affordable systems on multiple scales, from individual households off‐grid communities.
Language: Английский
Citations
43
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 272, P. 132583 - 132583
Published: May 23, 2024
Language: Английский
Citations
21
Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 147, P. 104471 - 104471
Published: March 29, 2024
Language: Английский
Citations
17
Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101509 - 101509
Published: Jan. 22, 2025
Articular cartilage, composed of chondrocytes within a dynamic viscoelastic matrix, has limited self-repair capacity, posing significant challenge for regeneration. Constructing high-fidelity cartilage organoids through three-dimensional (3D) bioprinting to replicate the structure and physiological functions is crucial regenerative medicine, drug screening, disease modeling. However, commonly used matrix bioinks lack reversible cross-linking precise controllability, hindering cellular regulation. Thus, encoding adaptive cultivating an attractive idea. DNA, with its ability be intricately encoded reversibly cross-linked into hydrogels, offers manipulation at both molecular spatial structural levels. This endows hydrogels viscoelasticity, printability, cell recognition, stimuli responsiveness. paper elaborates on strategies encode bioink via emphasizing regulation predictable properties resulting interactions behavior. The significance these construction highlighted. Finally, we discuss challenges future prospects using DNA-encoded 3D bioprinted organoids, underscoring their potential impact advancing biomedical applications.
Language: Английский
Citations
2
Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 294, P. 119763 - 119763
Published: June 22, 2022
Language: Английский
Citations
64
Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 300, P. 120267 - 120267
Published: Oct. 30, 2022
Language: Английский
Citations
56
Pharmaceuticals, Journal Year: 2022, Volume and Issue: 15(10), P. 1282 - 1282
Published: Oct. 19, 2022
Advancements in the material design of smart hydrogels have transformed way therapeutic agents are encapsulated and released biological environments. On other hand, expeditious development 3D printing technologies has revolutionized fabrication hydrogel systems for biomedical applications. By combining these two aspects, 4D (i.e., hydrogels) emerged as a new promising platform novel controlled drug delivery that can adapt mimic natural physio-mechanical changes over time. This allows printed objects to transform from static dynamic response various physiological chemical interactions, meeting needs healthcare industry. In this review, we provide an overview innovation systems, current technical approaches toward printing, emerging structures Finally, discuss existing challenges their prospects.
Language: Английский
Citations
43
Gels, Journal Year: 2023, Volume and Issue: 9(12), P. 960 - 960
Published: Dec. 7, 2023
Hydrogels have emerged as a versatile and promising class of materials in the field 3D printing, offering unique properties suitable for various applications. This review delves into intersection hydrogels exploring current research, technological advancements, future directions. It starts with an overview hydrogel basics, including composition properties, details used printing. The explores diverse printing methods hydrogels, discussing their advantages limitations. emphasizes integration 3D-printed biomedical engineering, showcasing its role tissue regenerative medicine, drug delivery. Beyond healthcare, it also examines applications food, cosmetics, electronics industries. Challenges like resolution limitations scalability are addressed. predicts trends material development, techniques, novel
Language: Английский
Citations
30
Biofabrication, Journal Year: 2023, Volume and Issue: 15(3), P. 035001 - 035001
Published: March 16, 2023
Abstract Microgels have recently received widespread attention for their applications in a wide array of domains such as tissue engineering, regenerative medicine, and cell transplantation because properties like injectability, modularity, porosity, the ability to be customized terms size, form, mechanical properties. However, it is still challenging mass (high-throughput) produce microgels with diverse sizes tunable Herein, we utilized an air-assisted co-axial device (ACAD) continuous production high-throughput manner. To test its robustness, multiple hydrogels combination, including alginate (Alg), gelatin methacrylate (GelMA) Alg–GelMA, were formed at maximum rate ∼65 000 s −1 while retaining circularity size range 50–500 µ m based on varying air pressure levels. The ACAD platform allowed single encapsulation 74 ± 6% efficiency. These illustrated appealing rheological yield stress, viscosity, shear modulus bioprinting applications. Specifically, Alg potential used sacrificial support bath GelMA direct extrusion both own or when loaded bulk hydrogel. Generated showed high viability (>90%) proliferation MDA-MB-231 human dermal fibroblasts over seven days scaffolding applications, particularly microgels. developed strategy provides facile rapid approach without any complex expensive consumables accessories scalable microgel therapy, regeneration 3D
Language: Английский
Citations
23