Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123

Published: Feb. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Language: Английский

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Combining Bacteriogenic Fluorescent Carbon Nanoparticles with ZnO Nanoparticles: A Novel Approach Against Antibiotic-Resistant Clinical Escherichia coli Strains

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 16, 2025

Language: Английский

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Synergistic antibacterial activity of chitosan-polyethylene glycol nanocomposites films containing ZIF-8 and doxycycline

BMC Biotechnology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 20, 2025

Antibiotic resistance is a growing global threat due to antibiotic overuse and limited treatment options. Multidrug-resistant bacteria, like Staphylococcus aureus Escherichia coli, increase infection complexity mortality. This study explores nanocomposite films of ZIF-8 nanoparticles Doxycycline (Dox) enhance antibacterial efficacy. In this study, composed chitosan (CS) polyethylene glycol (PEG), incorporating zeolitic imidazolate framework-8 (ZIF-8) DOX, were developed. These characterized by their morphological, mechanical, antibacterial, drug-release properties. Antibacterial efficacy was evaluated using disk diffusion, broth microdilution, checkerboard assay methods determine MICs potential synergistic effects. The demonstrated flexibility, semi-transparency, yellowish-brown hue, with containing being thicker (79 ± 0.2 μm) than those without (54 0.5 μm). tensile strength enhanced the incorporation ZIF-8, peaking at 53.12 MPa for CS-PEG-G-10% DOX-4% film. XRD analysis confirmed crystallinity distinct peaks observed each material. drug release studies revealed an initial burst followed sustained release, higher rates in acidic environments compared neutral alkaline media. film significantly activity, achieving lowest MIC values, particularly against S. (22.5 mm inhibition zone) E. coli (14 zone). Additionally, notable effect between DOX FICI values below 0.5. exhibits optimal properties, positioning it as strong candidate developing effective treatments multidrug-resistant pathogens.

Language: Английский

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Bacterial synthesis of metal nanoparticles as antimicrobials

Microbial Biotechnology, Journal Year: 2024, Volume and Issue: 17(8)

Published: Aug. 1, 2024

Nanoscience, a pivotal field spanning multiple industries, including healthcare, focuses on nanomaterials characterized by their dimensions. These materials are synthesized through conventional chemical and physical methods, often involving costly energy-intensive processes. Alternatively, biogenic synthesis using bacteria, fungi, or plant extracts offers potentially sustainable non-toxic approach for producing metal-based nanoparticles (NP). This eco-friendly not only reduces environmental impact but also enhances features of NP production due to the unique biochemistry biological systems. Recent advancements have shown that along with chemically NPs, NPs possess significant antimicrobial properties. The inherent bacteria enables efficient conversion metal salts into reduction processes, which further stabilized biomolecular capping layers improve biocompatibility functional mini review explores use produce activities. Microbial technologies antimicrobials considerable potential help address resistance crisis, thus addressing critical health issues aligned United Nations Sustainability Goal #3 good well-being.

Language: Английский

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Bio-Inspired Facile Synthesis of CeO2-TiO2 nanocomposites using calyx leaves extract of Physalis peruviana fruits and their Biological Assessments: Antibacterial and Antioxidant activity

Plant Nano Biology, Journal Year: 2024, Volume and Issue: unknown, P. 100130 - 100130

Published: Dec. 1, 2024

Language: Английский

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