A Multifunctional Nanozyme Hydrogel with Antibacterial, Antioxidative, and Photo-Induced Nitric Oxide-Supplying Properties for Promoting Infected Wound Healing DOI Creative Commons
Wen Zuo, Kunpeng Wei, Xinyi Zhang

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(12), P. 1624 - 1624

Published: Dec. 22, 2024

Objectives: To design a multifunctional nanozyme hydrogel with antibacterial, photo-responsive nitric oxide-releasing, and antioxidative properties for promoting the healing of infected wounds. Methods: We first developed ultra-small silver nanoparticles (NPs)-decorated sodium nitroprusside-doped Prussian blue (SNPB) NPs, referred to as SNPB@Ag which served nanozyme. Subsequently, this nanozyme, together geniposide (GE), was incorporated into thermo-sensitive hydrogel, formulated from Poloxamer 407 carboxymethyl chitosan, creating novel antibacterial wound dressing designated GE/SNPB@Ag hydrogel. The physical were systematically investigated. Results: After embedding GE, resulting retains its thermosensitive exhibits sustained release characteristics. In addition catalase-like activity, demonstrates high photothermal conversion efficiency, photo-induced oxide release, activity. addition, favorable antioxidant biocompatibility. results animal experiments demonstrate that composite combined laser irradiation is an effective method healing. Conclusions: vitro in vivo studies indicate holds significant potential treatment wounds further clinical applications.

Language: Английский

Dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis DOI

Chi Lin,

Tsai-Mu Cheng, Yunchun Liu

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 493, P. 152755 - 152755

Published: June 1, 2024

Language: Английский

Citations

6
Prussian blue-decorated indocyanine green-loaded mesoporous silica nanohybrid for synergistic photothermal-photodynamic-chemodynamic therapy against methicillin-resistant Staphylococcus aureus DOI

Chenyang Qi,

Guitao Tan,

Haonan Hu

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 241, P. 114065 - 114065

Published: June 27, 2024

Language: Английский

Citations

4
Prussian Blue Based Nanomaterials for Bacterial Detection and Killing Application DOI

Huidan Li,

Hui Cui, Yuying Zhang

et al.

ACS Materials Letters, Journal Year: 2025, Volume and Issue: unknown, P. 595 - 609

Published: Jan. 16, 2025

The Prussian blue (PB) based nanomaterials have excellent photophysical and chemical properties, including strong photothermal conversion ability, multiple catalytic activities, porous structure, high specific surface area, good stability. Furthermore, as an FDA-approved antidote for heavy metal radioactive element poisoning, PB-based do not provoke significant immune responses or other adverse effects, demonstrating biocompatibility. its analogues (PB/PBAs) possess unique optical allowing the construction of highly sensitive biosensors disease diagnosis phototherapy. With advances in nanotechnology, a variety nanoplatforms on PB/PBAs been developed detection bacterial killing. This review mainly introduces synthesis methods summarizes research progress killing bacteria recent years. Finally, paper further discusses existing challenges adjustment directions related to current research, providing guidance future nanoplatform.

Language: Английский

Citations

0
Bioinspired Assembly of Natural Polyphenol-Amino Acid Surfactants as Multifunctional Durable Coatings for Anticorrosion Fruit Packaging DOI
Ting Du, Li Xiang, Shuo Shi

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Challenges emerge in the quest for highly efficient and biocompatible coatings to tackle microbial contamination. Here, we propose a bioinspired paradigm combining (-)-epigallocatechin gallate (EGCG) l-arginine surfactants (LAM) as all-green building blocks advanced with superior performance. Molecular dynamics simulations reveal natural assembly process of EGCG/LAM supramolecular nanoparticles (ELA NPs). Notably, retain 99.0% antimicrobial activity even after eight cycles use exhibit adhesive anti-water washing properties, maintaining their efficacy uses 30 days water soaking on various substrates. When applied sustainable food packaging perishable fruits at room temperature, ELA significantly extend shelf life strawberries cherry tomatoes, reducing weight loss firmness sweetness. This study demonstrates potential NPs versatile durable coating materials mitigating waste agricultural economic losses due pollution.

Language: Английский

Citations

0
Copper peroxide-decorated Prussian blue for effective bacterial elimination via photothermal-enhanced and H2O2-releasing chemodynamic therapy DOI

Guitao Tan,

Chenyang Qi,

Qinqin Zhang

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 376, P. 899 - 912

Published: Nov. 6, 2024

Language: Английский

Citations

3
Phototheranostics: An Advanced Approach for Precise Diagnosis and Treatment of Gynecological Inflammation and Tumors DOI
Qihang Ding,

A. Guo,

Shuai Zhang

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 316, P. 123012 - 123012

Published: Dec. 15, 2024

Language: Английский

Citations

3
A Multifunctional Nanozyme Hydrogel with Antibacterial, Antioxidative, and Photo-Induced Nitric Oxide-Supplying Properties for Promoting Infected Wound Healing DOI Creative Commons
Wen Zuo, Kunpeng Wei, Xinyi Zhang

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(12), P. 1624 - 1624

Published: Dec. 22, 2024

Objectives: To design a multifunctional nanozyme hydrogel with antibacterial, photo-responsive nitric oxide-releasing, and antioxidative properties for promoting the healing of infected wounds. Methods: We first developed ultra-small silver nanoparticles (NPs)-decorated sodium nitroprusside-doped Prussian blue (SNPB) NPs, referred to as SNPB@Ag which served nanozyme. Subsequently, this nanozyme, together geniposide (GE), was incorporated into thermo-sensitive hydrogel, formulated from Poloxamer 407 carboxymethyl chitosan, creating novel antibacterial wound dressing designated GE/SNPB@Ag hydrogel. The physical were systematically investigated. Results: After embedding GE, resulting retains its thermosensitive exhibits sustained release characteristics. In addition catalase-like activity, demonstrates high photothermal conversion efficiency, photo-induced oxide release, activity. addition, favorable antioxidant biocompatibility. results animal experiments demonstrate that composite combined laser irradiation is an effective method healing. Conclusions: vitro in vivo studies indicate holds significant potential treatment wounds further clinical applications.

Language: Английский

Citations

0