Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer DOI
Katelyn D. Miller, Seamus O’Connor, Katherine Pniewski

et al.

Nature Cancer, Journal Year: 2023, Volume and Issue: 4(10), P. 1491 - 1507

Published: Sept. 18, 2023

Language: Английский

Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy DOI
Andrew Maltez Thomas, Marine Fidelle, Bertrand Routy

et al.

Nature Reviews Clinical Oncology, Journal Year: 2023, Volume and Issue: 20(9), P. 583 - 603

Published: June 26, 2023

Language: Английский

Citations

73
Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles DOI Creative Commons

Mukeng Hong,

Zhuang Li, Haihua Liu

et al.

Cell Host & Microbe, Journal Year: 2023, Volume and Issue: 31(5), P. 798 - 810.e7

Published: April 12, 2023

Language: Английский

Citations

69
Control of tumor-associated macrophage responses by nutrient acquisition and metabolism DOI Creative Commons
Xian Zhang, Liangliang Ji, Ming O. Li

et al.

Immunity, Journal Year: 2023, Volume and Issue: 56(1), P. 14 - 31

Published: Jan. 1, 2023

Language: Английский

Citations

66
Amino acid metabolism in tumor biology and therapy DOI Creative Commons
Jie Chen,

Likun Cui,

Shaoteng Lu

et al.

Cell Death and Disease, Journal Year: 2024, Volume and Issue: 15(1)

Published: Jan. 13, 2024

Abstract Amino acid metabolism plays important roles in tumor biology and therapy. Accumulating evidence has shown that amino acids contribute to tumorigenesis immunity by acting as nutrients, signaling molecules, could also regulate gene transcription epigenetic modification. Therefore, targeting will provide new ideas for treatment become an therapeutic approach after surgery, radiotherapy, chemotherapy. In this review, we systematically summarize the recent progress of malignancy their interaction with signal pathways well effect on microenvironment Collectively, highlight potential application future expectation.

Language: Английский

Citations

64
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer DOI
Katelyn D. Miller, Seamus O’Connor, Katherine Pniewski

et al.

Nature Cancer, Journal Year: 2023, Volume and Issue: 4(10), P. 1491 - 1507

Published: Sept. 18, 2023

Language: Английский

Citations

58