Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Aug. 29, 2024
Remarkable
progress
has
been
achieved
in
sepsis
treatment
recent
times,
the
mortality
rate
of
experienced
a
gradual
decline
as
result
prompt
administration
antibiotics,
fluid
resuscitation,
and
implementation
various
therapies
aimed
at
supporting
multiple
organ
functions.
However,
there
is
still
significant
room
for
improvement.
The
septic
patients,
22.5%,
unacceptably
high,
accounting
19.7%
all
global
deaths.
Therefore,
it
crucial
to
thoroughly
comprehend
pathogenesis
order
enhance
clinical
diagnosis
methods.
Here,
we
summarized
classic
mechanisms
progression,
activation
signal
pathways,
mitochondrial
quality
control,
imbalance
pro-and
anti-
inflammation
response,
diseminated
intravascular
coagulation
(DIC),
cell
death,
presented
latest
research
findings
each
mechanism
identify
potential
therapeutic
targets
within
mechanism.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(20), P. 3530 - 3530
Published: Oct. 18, 2024
As
an
ancient
concept
and
practice,
"food
as
medicine"
or
"medicine-food
homology"
is
receiving
more
attention
these
days.
It
a
tradition
in
many
regions
to
intake
medicinal
herbal
food
for
potential
health
benefits
various
organs
systems
including
the
kidney.
Kidney
diseases
usually
lack
targeted
therapy
face
irreversible
loss
of
function,
leading
dialysis
dependence.
most
important
organ
endogenous
metabolite
exogenous
nutrient
excretion,
status
kidney
could
be
closely
related
daily
diet.
Therefore,
rich
antioxidative,
anti-inflammation
micronutrients
are
ideal
supplements
protection.
Recent
studies
have
also
discovered
its
impact
on
"gut-kidney"
axis.
Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(9), P. 249 - 249
Published: Aug. 29, 2024
Acute
kidney
injury
(AKI)
is
the
most
severe
and
fatal
complication
of
sepsis
resulting
from
infectious
trauma.
Currently,
effective
treatment
options
are
still
lacking.
Dihydromyricetin
main
component
extracted
Vine
tea
(
Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Aug. 29, 2024
Remarkable
progress
has
been
achieved
in
sepsis
treatment
recent
times,
the
mortality
rate
of
experienced
a
gradual
decline
as
result
prompt
administration
antibiotics,
fluid
resuscitation,
and
implementation
various
therapies
aimed
at
supporting
multiple
organ
functions.
However,
there
is
still
significant
room
for
improvement.
The
septic
patients,
22.5%,
unacceptably
high,
accounting
19.7%
all
global
deaths.
Therefore,
it
crucial
to
thoroughly
comprehend
pathogenesis
order
enhance
clinical
diagnosis
methods.
Here,
we
summarized
classic
mechanisms
progression,
activation
signal
pathways,
mitochondrial
quality
control,
imbalance
pro-and
anti-
inflammation
response,
diseminated
intravascular
coagulation
(DIC),
cell
death,
presented
latest
research
findings
each
mechanism
identify
potential
therapeutic
targets
within
mechanism.
