Peripheral blood complement factors C2 and C3 as biomarkers of clinical efficacy in patients with first-episode schizophrenia after aripiprazole treatment DOI Creative Commons
Yin Cao, Jun Liang, Biao Dai

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 31, 2024

Language: Английский

Inflammatory bowel disease and neuropsychiatric disorders: Mechanisms and emerging therapeutics targeting the microbiota-gut-brain axis DOI Creative Commons

Guido Petracco,

Isabella Faimann, Florian Reichmann

et al.

Pharmacology & Therapeutics, Journal Year: 2025, Volume and Issue: unknown, P. 108831 - 108831

Published: Feb. 1, 2025

Language: Английский

Citations

0
Interaction between serum inflammatory cytokines and brain-derived neurotrophic factor in cognitive function among first-episode schizophrenia patients DOI Open Access
Lijun Cui,

Lili Cai,

Wan-Qiu Na

et al.

World Journal of Psychiatry, Journal Year: 2024, Volume and Issue: 14(12), P. 1804 - 1814

Published: Nov. 27, 2024

BACKGROUND The pathogenesis of cognitive impairment in schizophrenia (SCZ) remains unclear. Accumulating studies showed that inflammatory-immune dysregulation and altered brain derived neurotrophic factor (BDNF) levels play a crucial role the psychopathology SCZ. However, their association with dysfunction first-episode SCZ patients has not been thoroughly investigated. AIM To explore interaction effects between function inflammatory cytokines BDNF METHODS current study is cross-sectional case-control investigation recruited 84 (SCZ group) 80 healthy controls (HCs at Huzhou Third Municipal Hospital August 2021 September 2023. ELISA was employed to measure serum interleukin (IL)-1β, IL-4, IL-6, IL-10, BDNF. Chinese brief test (C-BCT) positive negative syndrome scales were measured severity psychiatric symptoms. RESULTS Compared HC group, group exhibited elevated IL-1β IL-6 levels, decreased reduced C-BCT scores (all P < 0.001). In SCZ, negatively correlated (r = -0.324, 0.05). Information processing speed -0.315, 0.05) positively 0.290, 0.05); attention, working memory, comprehensive ability, executive Multiple regression analysis influenced dimensions (β -0.218 -0.327, all attention ability by -0.199 -0.261, ; 0.209, . CONCLUSION Our findings suggested interrelationships immune deficiency might underlie pathological mechanisms impairments patients.

Language: Английский

Citations

3
Investigation of the Protective Effects of Aripiprazole on Methylphenidate-induced Neurotoxicity in Rats DOI

Afrooz Mohammadgholi-Beiki,

Helia Aghamiri,

Rojin Rashidian

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Language: Английский

Citations

0
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways DOI

Helia Aghamiri,

Afrooz Mohammadgholi-Beiki,

Rojin Rashidian

et al.

Inflammopharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 23, 2024

Language: Английский

Citations

0
Peripheral blood complement factors C2 and C3 as biomarkers of clinical efficacy in patients with first-episode schizophrenia after aripiprazole treatment DOI Creative Commons
Yin Cao, Jun Liang, Biao Dai

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 31, 2024

Language: Английский

Citations

0