Calcium signaling in chemotherapy-induced neuropathy DOI
Matheus de Castro Fonseca,

Paulo HS. Marazzi-Diniz,

M. Fátima Leite

et al.

Cell Calcium, Journal Year: 2023, Volume and Issue: 113, P. 102762 - 102762

Published: May 20, 2023

Language: Английский

Therapeutic Prospect of New Probiotics in Neurodegenerative Diseases DOI Creative Commons

Mingxia Bi,

Chang Liu, Yulin Wang

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(6), P. 1527 - 1527

Published: June 8, 2023

Increasing clinical and preclinical evidence implicates gut microbiome (GM) dysbiosis as a key susceptibility factor for neurodegenerative disorders, including Alzheimer’s disease (AD) Parkinson’s (PD). In recent years, diseases have been viewed being driven not solely by defects in the brain, role of GM modulating central nervous system function via gut–brain axis has attracted considerable interest. Encouraged current research, development new probiotics may lead to tangible impacts on treatment disorders. This review summarizes understandings composition characteristics associated with research demonstrations molecules from that affect neurodegeneration. Furthermore, applications probiotics, such Clostridium butyricum, Akkermansia muciniphila, Faecalibacterium prausnitzii, Bacteroides fragilis, remediation are discussed.

Language: Английский

Citations

10
Research Progress of Microbiota-Gut-Brain Axis in Parkinson's Disease DOI Creative Commons
Wei Zhang,

Y Ye,

Jiayang Song

et al.

Journal of Integrative Neuroscience, Journal Year: 2023, Volume and Issue: 22(6)

Published: Oct. 30, 2023

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by misfolding of α-synuclein. Clinical manifestations include slowly developing resting tremor, muscle rigidity, bradykinesia and abnormal gait. The pathological mechanisms underlying PD are complex yet to be fully elucidated. studies suggest that the onset gastrointestinal symptoms may precede motor in patients. microbiota-gut-brain axis plays bidirectional communication role between enteric nervous system central system. This brain gut influenced neural, immune endocrine systems related microbiome. A growing body evidence indicates strong link dysregulation microbiota PD. In this review, we present recent progress understanding relationship We focus on microbiota, unique changes observed microbiome patients, impact these progression Finally, evaluate current treatment strategies for PD, including probiotics, fecal microbial transplants, dietary modifications, drug therapies.

Language: Английский

Citations

10
Effects of pasteurized Akkermansia muciniphila on lipid metabolism disorders induced by high-fat diet in zebrafish (Danio rerio) DOI Creative Commons

Zhenyi Huang,

Yawei Wang,

Shikun Feng

et al.

Aquaculture Reports, Journal Year: 2024, Volume and Issue: 38, P. 102363 - 102363

Published: Sept. 13, 2024

Language: Английский

Citations

3
The multifaceted roles of Akkermansia muciniphila in neurological disorders DOI
Xin Ma, Wei Liu, Guan Yang

et al.

Trends in Neurosciences, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
Calcium signaling in chemotherapy-induced neuropathy DOI
Matheus de Castro Fonseca,

Paulo HS. Marazzi-Diniz,

M. Fátima Leite

et al.

Cell Calcium, Journal Year: 2023, Volume and Issue: 113, P. 102762 - 102762

Published: May 20, 2023

Language: Английский

Citations

8