Quantum-mechanic study of protein E of SARS-CoV-2 as a new potential candidate in therapeutic development to combat prolonged COVID-19 DOI
Juan Carlos Santiago-Jiménez,

Krisselby Ivonne Jiménez-Santiago,

Gabriel Ramírez-Damaso

et al.

MRS Advances, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Language: Английский

Efficacy of Donepezil for Fatigue and Psychological Symptoms in Post-COVID-19 Condition: Study Protocol for a Multicenter Randomized, Placebo-controlled, Double-blind Trial DOI Creative Commons
Keiichiro Kawabata, Kensuke Nakamura,

Kazuhiro Kondo

et al.

Annals of Clinical Epidemiology, Journal Year: 2024, Volume and Issue: 6(4), P. 87 - 96

Published: July 17, 2024

Approximately 30% of coronavirus disease 2019 COVID-19 patients develop fatigue and psychological symptoms. We previously demonstrated the efficacy donepezil, an acetylcholinesterase inhibitor that is widely used to treat dementia, in basic research.

Language: Английский

Citations

1
Multifocal meningoencephalitis after vaccination against COVID‐19 DOI
Shuji Mikami,

Mitsuru Ishii,

Tetsuhiro Yano

et al.

Pathology International, Journal Year: 2024, Volume and Issue: 74(12), P. 697 - 703

Published: Nov. 21, 2024

Abstract We report the case of an 84‐year‐old male patient who was transferred to our hospital because impaired consciousness and high fever, died about 10 weeks after his fourth “coronavirus disease 2019” (COVID‐19) vaccination. Autopsy revealed acute ischemic change with microhemorrhage perivascular T‐cell infiltration in thalamus, pons, cerebellum, which were considered be related neurological symptoms. There dilatation right ventricle, accumulation pleural effusion, ascites, suggesting heart failure. Although had a negative COVID‐19 polymerase chain reaction test, immunohistochemical analysis for severe respiratory syndrome coronavirus 2 (SARS‐CoV‐2) antigens (spike nucleocapsid proteins) performed identify cause death. Surprisingly, only SARS‐CoV‐2 spike protein detected pituitary adrenal glands. The presence might have been due vaccination rather than viral infection, no detected. central nervous system change, that glands may associated failure, possibly through dysfunction renin‐angiotensin‐aldosterone system.

Language: Английский

Citations

0
Comparative quantum-mechanical characterization of the molecules acacetin and curcumin to understand their antioxidant, anti-inflammatory, anticancer, and neuroprotective functions DOI Creative Commons
Juan Carlos Santiago-Jiménez,

Guadalupe Ortiz-Cabrera,

Gabriel Ramírez-Damaso

et al.

MRS Advances, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Language: Английский

Citations

0
Quantum-mechanic study of protein E of SARS-CoV-2 as a new potential candidate in therapeutic development to combat prolonged COVID-19 DOI
Juan Carlos Santiago-Jiménez,

Krisselby Ivonne Jiménez-Santiago,

Gabriel Ramírez-Damaso

et al.

MRS Advances, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Language: Английский

Citations

0