Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review

European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: July 25, 2024

Abstract Post-COVID syndrome (PCS) describes a persistent complex of symptoms following COVID-19 episode, lasting at least 4 to 12 weeks, depending on the specific criteria used for its definition. It is often associated with moderate severe impairments daily life and represents major burden many people worldwide. However, especially during first two years pandemic, therapeutic diagnostic uncertainties were prominent due novelty disease non-specific definitions that overlooked functional deficits lacked objective assessment. The present work comprehensively examines status PCS as depicted in recent reviews meta-analyses, alongside exploring impairments. We searched database Pubmed meta-analysis evaluating period between May 31, 2022, December 2023. Out 95 studies, 33 selected inclusion our analyses. Furthermore, we extended upon prior research by systematically recording linked identified studies. found fatigue, neurological complaints, exercise intolerance most frequently reported symptoms. In conclusion, over past eighteen months, there has been notable increase quantity quality studies PCS. still remains clear need improvement, particularly regard definition necessary diagnosing this syndrome. Enhancing aspect will render future more comparable precise, thereby advancing understanding

Language: Английский

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Expanding the understanding of tirofiban treatment in posterior circulation stroke: a call for further investigation

Clinical Neurology and Neurosurgery, Journal Year: 2025, Volume and Issue: 250, P. 108808 - 108808

Published: Feb. 20, 2025

Language: Английский

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A Comprehensive Review of the Global Epidemiology, Clinical Management, Socio-Economic Impacts, and National Responses to Long COVID with Future Research Directions

Diagnostics, Journal Year: 2024, Volume and Issue: 14(11), P. 1168 - 1168

Published: May 31, 2024

Long COVID, characterized by a persistent symptom spectrum following SARS-CoV-2 infection, poses significant health, social, and economic challenges. This review aims to consolidate knowledge on its epidemiology, clinical features, underlying mechanisms guide global responses;

Language: Английский

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Long-term outcomes of patients with Parkinson’s disease 3.5 years post SARS-CoV-2 infection in an inner-city population in the Bronx

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: May 28, 2024

Objectives. Although patients with pre-existing Parkinson’s disease (PD) are at a higher risk of severe acute COVID-19 outcomes compared to matched controls, the long-term PD post SARS-CoV2 infection largely unknown. This study investigated clinical up 3.5 years post-infection in an inner-city population Bronx, New York. Methods. retrospective evaluated 3,512 Montefiore Health System Bronx (January 2016 July 2023), which serves large Black and Hispanic was epicenter early pandemic subsequent surges infections. status defined by positive polymerase-chain-reaction test. Comparisons were made without Outcomes post-index date all-cause mortality, major adverse cardiovascular events (MACE), altered mental status, fatigue, dyspnea, headache, psychosis, dementia, depression, anxiety, dysphagia, falls, orthostatic hypotension. Changes Levodopa, medication, prescriptions also tabulated. Adjusted hazard ratios (aHR) computed accounting for competing risks. Results. About 14% had similar demographics but prevalence comorbidities neurological disorders COVID-19. greater mortality (aHR = 1.58 [95% CI:1.03,2.41] P 0.03), MACE (HR 1.57[95% CI:1.19,2.07], P < 0.005), dyspnea 1.44 [1.11,1.87], 0.01), fatigue 1.49 [1.12,1.97] headache 1.35 [1.01,1.80] 0.04), fall 1.39 [1.01, 1.92] 0.04) index-date. Levodopa equivalent dose adjustment cohort non-COVID-19 (P 0.04). Conclusions. worse Patients who survive may benefit from heightened awareness close follow-up.

Language: Английский

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Sleep and mental health during the COVID-19 pandemic: findings from an online questionnaire survey in China

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: June 17, 2024

Introduction The online study investigated the sleep, psychological conditions, and risk factors during wave of transmission COVID-19 since December 7, 2022. Methods We distributed questionnaires through networking mediums to residents gather information about infection, mental status. Results During extraordinary period in China, 91.9% 1094 participants claimed be infected with COVID-19, 36.8% reported poor sleep quality, 75.9% anxiety, 65.5% depression. In retrospect, people have experienced lower longer latency, enhanced rising time, decreased efficiency after infection wave. After adjusting confounding factors, elderly, women, urban residents, comorbidity, depression, stress state, high risks for disorders period. Discussion survey indicates that disturbance caused by involves multiple dimensions, such as physiology, psychology, society. infection-related problem should taken seriously. Apart from conventional treatment, issues insomnia can not ignored.

Language: Английский

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Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review

Published: April 25, 2024

Post-COVID syndrome (PCS) describes a persistent complex of symptoms following COVID-19 episode, lasting at least 4 to 12 weeks, depending on the specific criteria used for its definition. It is often associated with moderate severe impairments daily life and represents major burden many people worldwide. However, especially during first two years pandemic, therapeutic diagnostic uncertainties were prominent due novelty disease non-specific definitions that overlooked functional deficits lacked objective assessment. The present work comprehensively examines status PCS as depicted in recent reviews meta-analyses, alongside exploring impairments. We searched database Pubmed meta-analysis evaluating period between May 31, 2022, December 2023. Out 95 studies, 33 selected inclusion our analyses. Furthermore, we extended upon prior research by systematically recording linked identified studies. found fatigue, neurological complaints, exercise intolerance most frequently reported symptoms. In conclusion, over past eighteen months, there has been notable increase quantity quality studies still remains clear need improvement, particularly regard definition necessary diagnosing this syndrome. Enhancing aspect will render future more comparable precise, thereby advancing understanding PCS.

Language: Английский

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Neuroimaging markers of cognitive fatigue in individuals with post-acute sequelae of SARS-CoV-2 infection

Brain and Cognition, Journal Year: 2024, Volume and Issue: 183, P. 106254 - 106254

Published: Dec. 12, 2024

Language: Английский

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