Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: May 6, 2025
Background
Depression
is
a
psychological
condition
in
adolescents
caused
by
various
factors.
Many
serious
consequences
can
be
associated
with
depression,
such
as
irritability,
emotional
instability,
and
suicide.
Meanwhile,
the
incidence
of
depression
suicide
among
was
also
affected
during
pandemic
COVID-19
2019.
This
phenomenon
adolescent
should
drawn
extensive
concern
community,
which
affects
their
physical
mental
health.
Main
body
review
describes
epidemiology,
high-risk
factors,
treatment
depression.
The
onset
probably
attributable
to
preterm
birth,
growth
environment,
genetic.
We
identify
that
pandemic,
initiated
late
2019,affects
Antidepressants
psychotherapy
are
conventional
treatments
for
depressive
disorders.
However,
it
controversial
whether
antidepressants
effective
safer
psychotherapy,
combination
two
could
provide
more
benefit
this
population
than
alone.
summarize
some
developed
novel
targets.
Improving
efficacy
safety
reduce
rate
primary
goal
clinical
research.
Existing
modalities
drugs
not
sufficient
achieve
demands,
so
new
therapeutic
targets
will
promising
patients.
Conclusion
A
variety
factors
contribute
adolescents.
Adolescent
mainly
treated
non-pharmacological.
guideline-recommended
used
if
uncontrolled
non-pharmacological,
but
adverse
drug
reactions
suicidal
ideation
closely
monitored.
BMJ Open,
Journal Year:
2025,
Volume and Issue:
15(1), P. e088944 - e088944
Published: Jan. 1, 2025
Objectives
To
assess
the
association
between
depression
and
suicide
attempt
(SA)
by
age
region.
Design
Cross-sectional
study.
Setting
First
Affiliated
Hospital
of
Wannan
Medical
College
from
January
2021
to
2022.
Participants
Hospitalised
patients.
Primary
outcome
measures
SA
was
primary
data
on
obtained
electronic
medical
records
hospitalised
Methods
analysis
In
this
study,
inpatients
2022
were
extracted
record
system
using
convenience
sampling
method.
According
exclusion
criteria,
7593
eligible
research
subjects
obtained.
Logistic
regression
used
SA,
combining
Subgroup
analyses
carried
out
relationship
age,
region
in
depressed
patients,
after
excluding
non-depressed
inspect
interaction
Finally,
further
comparisons
disparities
patterns
among
different
groups
regional
made.
Results
Among
patients
(3630
males),
655
(8.6%)
with
observed.
We
found
that
significantly
associated
(all
p<0.05).
Specifically,
juveniles
adults
had
a
higher
risk
compared
adults,
ORs
(95%
CIs)
2.62
(1.59
4.30)
1.67
(1.30
2.13),
respectively.
Furthermore,
rural
individuals
depression,
urban
without
participants
1.60
(1.22
2.12),
1.29
(1.04
1.61)
2.53
(1.83
3.49),
subgroup
analyses,
we
strongly
(OR
2.84,
95%
CI
1.19
6.76,
p=0.018)
1.67,
1.15
2.40,
p=0.006).
Notably,
predominant
methods
utilisation
sleeping
pills
or
antidepressants.
Conclusion
Our
study
are
at
especially
individuals.
Effective
integration
mental
health
urban–rural
services
could
mitigate
contribute
better
outcomes.
Frontiers in Nutrition,
Journal Year:
2025,
Volume and Issue:
12
Published: March 10, 2025
Background
Adolescent
psychosocial
symptoms
continue
to
rise,
negatively
affecting
academic
performance
and
future
achievement,
have
become
an
important
public
health
issue
of
common
concern
worldwide.
However,
few
studies
been
conducted
on
the
association
between
body
roundness
index
(BRI)
sugar-sweetened
beverage
(SSB)
consumption
psychological
in
Chinese
adolescents.
The
present
study
may
provide
implications
for
intervention
prevention
Methods
In
this
study,
47,520
adolescents
aged
12–18
years
from
six
geographic
regions
China
were
assessed
cross-sectionally
BRI,
SSB
consumption,
2023.
Independent
samples
t-tests,
chi-square
tests,
logistic
regression
analyses,
ordered
analyses
used
compare
analyze
associations
that
existed
BRI
among
Results
was
(2.03
±
0.94).
proportions
with
≤1
times/week,
2–3
≥
4
times/week
33.2,
52.0,
14.7%,
respectively,
differences
statistically
significant
comparison
(
X
2
value
597.860,
p
<
0.001).
prevalence
19.2%.
rates
emotional
problems,
behavioral
social
adjustment
difficulties
26.1,
25.2,
16.1%,
respectively.
After
adjusting
relevant
covariates,
analysis
showed
quartiles
Q1
as
reference
group,
group
Q4
≥4
(OR
=
2.01,
95%
CI:
1.77–2.30)
had
highest
risk
developing
Conclusion
There
is
higher
at
symptoms.
future,
increase
should
be
effectively
controlled
prevent
or
reduce
occurrence
