JMIR Research Protocols,
Journal Year:
2024,
Volume and Issue:
13, P. e53857 - e53857
Published: Feb. 22, 2024
Background
Computational
psychiatry
has
the
potential
to
advance
diagnosis,
mechanistic
understanding,
and
treatment
of
mental
health
conditions.
Promising
results
from
clinical
samples
have
led
calls
extend
these
methods
risk
assessment
in
general
public;
however,
data
typically
used
with
are
neither
available
nor
scalable
for
research
population.
Digital
phenotyping
addresses
this
by
capitalizing
on
multimodal
widely
created
sensors
embedded
personal
digital
devices
(eg,
smartphones)
is
a
promising
approach
extending
computational
improve
Objective
Building
recommendations
existing
work,
we
aim
create
first
set
that
tailored
studying
population;
includes
multimodal,
sensor-based
behavioral
features;
designed
be
shared
across
academia,
industry,
government
using
gold
standard
privacy,
confidentiality,
integrity.
Methods
We
stratified,
random
sampling
design
2
crossed
factors
(difficulties
emotion
regulation
perceived
life
stress)
recruit
sample
400
community-dwelling
adults
balanced
high-
low-risk
episodic
Participants
complete
self-report
questionnaires
assessing
current
lifetime
psychiatric
medical
diagnoses
treatment,
psychosocial
functioning.
then
7-day
situ
collection
phase
providing
daily
audio
recordings,
passive
sensor
collected
smartphones,
self-reports
mood
significant
events,
verbal
description
events
during
nightly
phone
call.
same
baseline
6
12
months
after
phase.
Self-report
will
scored
methods.
Raw
processed
suite
summary
features
time
spent
at
home).
Results
Data
began
June
2022
expected
conclude
July
2024.
To
date,
310
participants
consented
study;
149
completed
questionnaire
intensive
phase;
61
31
6-
12-month
follow-up
questionnaires,
respectively.
Once
completed,
proposed
made
academic
researchers,
stepped
maximize
privacy.
Conclusions
This
as
complementary
research,
goal
advancing
within
aims
support
field’s
move
away
siloed
laboratories
collecting
proprietary
toward
interdisciplinary
collaborations
incorporate
clinical,
technical,
quantitative
expertise
all
stages
process.
International
Registered
Report
Identifier
(IRRID)
DERR1-10.2196/53857
JMIR Mental Health,
Journal Year:
2025,
Volume and Issue:
12, P. e65143 - e65143
Published: Jan. 7, 2025
Background
Digital
wearable
devices,
worn
on
or
close
to
the
body,
have
potential
for
passively
detecting
mental
and
physical
health
symptoms
among
people
with
severe
illness
(SMI);
however,
roles
of
consumer-grade
devices
are
not
well
understood.
Objective
This
study
aims
examine
utility
data
from
consumer-grade,
digital,
(including
smartphones
wrist-worn
devices)
remotely
monitoring
predicting
changes
in
adults
schizophrenia
bipolar
disorder.
Studies
were
included
that
collected
physiological
sleep
duration,
heart
rate,
wake
patterns,
activity)
at
least
3
days.
Research-grade
actigraphy
methods
physically
obtrusive
excluded.
Methods
We
conducted
a
systematic
review
following
databases:
Cochrane
Central
Register
Controlled
Trials,
Technology
Assessment,
AMED
(Allied
Complementary
Medicine),
APA
PsycINFO,
Embase,
MEDLINE(R),
IEEE
XPlore.
Searches
completed
May
2024.
Results
synthesized
narratively
due
heterogeneity
divided
into
phenotypes:
activity,
circadian
rhythm,
rate.
Overall,
23
studies
reported
12
distinct
studies,
mostly
using
centered
relapse
prevention.
Only
1
explicitly
aimed
address
outcomes
SMI.
In
total,
over
500
participants
SMI,
predominantly
high-income
countries.
Most
commonly,
papers
presented
activity
(n=18),
followed
by
rhythm
(n=14)
rate
(n=6).
The
use
smartwatches
support
collection
8
papers;
rest
used
only
smartphones.
There
was
some
evidence
lower
levels
higher
rates,
later
irregular
onset
times
associated
psychiatric
diagnoses
poorer
symptoms.
However,
measures,
sampling
statistical
approaches
complicated
interpretation.
Conclusions
Consumer-grade
wearables
show
ability
detect
digital
markers
indicative
status
but
few
currently
these
inequalities.
phenotyping
field
psychiatry
would
benefit
moving
toward
agreed
standards
regarding
descriptions
outcome
measures
ensuring
valuable
temporal
provided
fully
exploited.
Trial
Registration
PROSPERO
CRD42022382267;
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=382267
IEEE Journal of Biomedical and Health Informatics,
Journal Year:
2024,
Volume and Issue:
28(3), P. 1680 - 1691
Published: Jan. 10, 2024
Psychiatric
evaluation
suffers
from
subjectivity
and
bias,
is
hard
to
scale
due
intensive
professional
training
requirements.
In
this
work,
we
investigated
whether
behavioral
physiological
signals,
extracted
tele-video
interviews,
differ
in
individuals
with
psychiatric
disorders.
The
past
decade
has
been
transformative
for
mental
health
research
and
practice.
ability
to
harness
large
repositories
of
data,
whether
from
electronic
records
(EHR),
mobile
devices,
or
social
media,
revealed
a
potential
valuable
insights
into
patient
experiences,
promising
early,
proactive
interventions,
as
well
personalized
treatment
plans.
Recent
developments
in
generative
artificial
intelligence,
particularly
language
models
(LLMs),
show
promise
leading
digital
uncharted
territory.
Patients
are
arriving
at
doctors'
appointments
with
information
sourced
chatbots,
state-of-the-art
LLMs
being
incorporated
medical
software
EHR
systems,
chatbots
an
ever-increasing
number
startups
serve
AI
companions,
friends,
partners.
This
article
presents
contemporary
perspectives
on
the
opportunities
risks
posed
by
design,
development,
implementation
tools.
We
adopt
ecological
framework
draw
affordances
offered
discuss
four
application
areas---care-seeking
behaviors
individuals
need
care,
community
care
provision,
institutional
larger
ecologies
societal
level.
engage
thoughtful
consideration
how
LLM-based
technologies
could
should
be
employed
enhancing
health.
benefits
harms
our
surfaces
help
shape
future
research,
advocacy,
regulatory
efforts
focused
creating
more
responsible,
user-friendly,
equitable,
secure
tools
intervention.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
2(2), P. 778 - 810
Published: Feb. 22, 2024
Mental
health
disorders—including
depression,
anxiety,
trauma-related,
and
psychotic
conditions—are
pervasive
impairing,
representing
considerable
challenges
for
both
individual
well-being
public
health.
Often
the
first
to
treatment
include
financial,
geographic,
stigmatic
barriers,
which
limit
accessibility
of
traditional
assessment
measures.
Further,
compounded
by
frequent
misdiagnosis
or
delayed
detection,
there
is
a
need
effective,
accessible,
scalable
approaches
identification
management.
Considering
advances
in
computing
ubiquitous
nature
personal
mobile
wearable
technology,
this
narrative
review
examines
utilization
passive
sensor
data
as
screening
diagnostic
tool
mental
disorders.
As
an
alternative
measures,
sensing
offers
overcome
barriers
that
prevent
many
from
seeking
services.
We
critically
assess
literature
up
September
2023,
exploring
use
data—such
heart
rate
variability,
movement
patterns,
geolocation—to
predict
outcomes
across
spectrum
From
translational
perspective,
our
explores
state
science,
with
special
emphasis
on
capacity
science
be
implemented
real
world
clinical
general
populations,
novelty
specific
best
knowledge.
Toward
aim,
we
consider
multiple
study
factors,
including
participant
demographics,
collection
methods,
modalities,
outcome
analytic
modeling
approaches.
find
features,
such
GPS,
rate,
actigraphy
offer
promise
enhancing
early
detection
improving
process
Despite
promise,
however,
findings
highlight
important
limitations
research
(1)
trend
toward
smaller,
specialized
samples,
(2)
predominance
apps
built
Android
operating
system,
(3)
reliance
self-reported
measures
proxies
outcomes.
These
ultimately
stymie
efforts
implement
scale
larger
more
heterogeneous
populations.
With
future
mind,
emphasize
importance
validating
larger,
diverse
samples
ensuring
tools
can
deployed
device
types
systems.
where
possible,
robust,
objectively
validated
clinician
assessment.
conclude
careful
consideration
factors
design
will
aid
impact
studies,
broad
scale.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(6), P. e0298949 - e0298949
Published: June 20, 2024
Loneliness
is
linked
to
wide
ranging
physical
and
mental
health
problems,
including
increased
rates
of
mortality.
Understanding
how
loneliness
manifests
important
for
targeted
public
treatment
intervention.
With
advances
in
mobile
sending
wearable
technologies,
it
possible
collect
data
on
human
phenomena
a
continuous
uninterrupted
way.
In
doing
so,
such
approaches
can
be
used
monitor
physiological
behavioral
aspects
relevant
an
individual’s
loneliness.
this
study,
we
proposed
method
detection
using
fully
objective
from
smart
devices
passive
sensing.
We
also
investigated
whether
features
differed
their
importance
predicting
across
individuals.
Finally,
examined
informative
each
device
tasks.
assessed
subjective
feelings
while
monitoring
patterns
30
college
students
over
2-month
period.
smartphones
(e.g.,
location
changes,
type
notifications,
in-coming
out-going
calls/text
messages)
watches
rings
physiology
sleep
heart-rate,
heart-rate
variability,
duration).
Participants
reported
feeling
multiple
times
day
through
questionnaire
app
phone.
Using
the
collected
devices,
trained
random
forest
machine
learning
based
model
detect
levels.
found
support
prediction
multi-device
fully-objective
approach.
Furthermore,
by
generally
were
most
all
participants.
The
study
provides
promising
results
indicators,
which
could
provide
source
information
healthcare
applications.
Human Brain Mapping,
Journal Year:
2024,
Volume and Issue:
45(4)
Published: March 1, 2024
Abstract
A
primary
goal
of
neuroscience
is
to
understand
the
relationship
between
brain
and
behavior.
While
magnetic
resonance
imaging
(MRI)
examines
structure
function
under
controlled
conditions,
digital
phenotyping
via
portable
automatic
devices
(PAD)
quantifies
behavior
in
real‐world
settings.
Combining
these
two
technologies
may
bridge
gap
imaging,
physiology,
real‐time
behavior,
enhancing
generalizability
laboratory
clinical
findings.
However,
use
MRI
data
from
PADs
outside
scanner
remains
underexplored.
Herein,
we
present
a
Preferred
Reporting
Items
for
Systematic
Reviews
Meta‐Analysis
systematic
literature
review
that
identifies
analyzes
current
state
research
on
integration
PADs.
PubMed
Scopus
were
automatically
searched
using
keywords
covering
various
techniques
Abstracts
screened
only
include
articles
collected
PAD
environment.
Full‐text
screening
was
then
conducted
ensure
included
combined
quantitative
with
PADs,
yielding
94
selected
papers
total
N
=
14,778
subjects.
Results
reported
as
cross‐frequency
tables
sampling
methods
patterns
identified
through
network
analysis.
Furthermore,
maps
studies
synthesized
according
measurement
modalities
used.
demonstrate
feasibility
integrating
across
study
designs,
patient
control
populations,
age
groups.
The
majority
published
combines
functional,
T1‐weighted,
diffusion
weighted
physical
activity
sensors,
ecological
momentary
assessment
sleep.
further
highlights
specific
regions
frequently
correlated
distinct
MRI‐PAD
combinations.
These
combinations
enable
in‐depth
how
influence
each
other.
Our
potential
constructing
brain–behavior
models
extend
beyond
into
contexts.
Frontiers in Psychology,
Journal Year:
2025,
Volume and Issue:
15
Published: Jan. 6, 2025
Digital
technologies,
including
smartphones,
hold
great
promise
for
expanding
mental
health
services
and
improving
access
to
care.
phenotyping,
which
involves
the
collection
of
behavioral
physiological
data
using
offers
a
novel
way
understand
monitor
health.
This
study
examines
feasibility
psychological
well-being
program
telegram-integrated
chatbot
digital
phenotyping.
A
one-month
randomized
non-clinical
trial
was
conducted
with
81
young
adults
aged
18-35
from
Italy
canton
Ticino,
region
in
southern
Switzerland.
Participants
were
an
experimental
group
that
interacted
chatbot,
or
control
received
general
information
on
well-being.
The
collected
real-time
participants'
such
as
user-chatbot
interactions,
responses
exercises,
emotional
metrics.
clustering
algorithm
created
user
profile
content
recommendation
system
provide
personalized
exercises
based
users'
responses.
Four
distinct
clusters
participants
emerged,
factors
online
alerts,
social
media
use,
insomnia,
attention
energy
levels.
reported
improvements
found
recommended
by
useful.
demonstrates
phenotyping-based
chatbot.
Despite
limitations
small
sample
size
short
duration,
findings
suggest
phenotyping
systems
could
improve
Future
research
should
include
larger
samples
longer
follow-up
periods
validate
these
explore
clinical
applications.