Chemoselective reductive coupling of α, β-unsaturated esters and nitroarenes for sustainable synthesis of β-amino acid esters by a hierarchically porous cobalt nanocatalyst DOI
Huanhuan Jia,

Junwei Xi,

Rong Xie

et al.

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 429, P. 115239 - 115239

Published: Dec. 5, 2023

Language: Английский

Recent Development in Synthesis of N‐Methylamines with Amines and Methanol DOI
Xiaogang Yu, Xinjiang Cui, Huanwang Jing

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: 16(16)

Published: March 23, 2024

Abstract The N‐methylation reaction of amines with methanol via the borrowing‐hydrogen strategy is an important method for construction C−N bonds. Compared other C1 sources, such as toxic formaldehyde or expensive formic acid, more suitable reactions due to its eco‐friendliness and low price. Using this strategy, various types N‐methylated products, including biological pharmaceutical molecules have been prepared. Here, we present a thorough survey decades articles showing current developments in methanol. We discuss homogenous, heterogenous light‐driven catalytic systems both N,N‐dimethylation reactions. This review presents shortcomings provides future development progress

Language: Английский

Citations

5
Iridium-catalyzed reductive γ-lactonization of ortho-acylbenzoic acids in water: sustainable access to phthalides DOI
Chen Yang, Jingyu Zhang, Hongguang Du

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(8), P. 2220 - 2230

Published: Jan. 1, 2024

Iridium-catalyzed reductive γ-lactonization of ortho -acylbenzoic acids in water provides a practical and sustainable route to phthalides.

Language: Английский

Citations

3
En Route to Diastereopure Polycyclic γ‐Lactones by Iridium‐Catalyzed Hydride Transfer† DOI Open Access
Yang Chen, Jingyu Zhang, Yecheng Wang

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(23), P. 3047 - 3055

Published: July 30, 2024

Comprehensive Summary The reductive lactonization strategy provides an efficient access to diastereoenriched polycyclic γ‐lactones. However, it is still a formidable challenge develop and versatile protocol with excellent levels of diastereocontrol. Herein, we provide highly diastereoselective route diastereopure bi‐ γ‐lactones, by means iridium‐catalyzed hydride transfer strategy. This method features high diastereocontrol, broad substrate scope, catalyst efficiency ( S / C = up 5000). Mechanistic studies suggest that the iridium formation might be rate‐determining step, step diastereo‐determining step. large steric hindrance species intramolecular hydrogen bonding are critically key diastereocontrol process. From perspectives configurational analysis Duniz angles attack, nature well rationalized. A more general empirical rule based on facial selectivity for explaining predicting stereochemistry also proposed.

Language: Английский

Citations

2
TsOH-catalyzed dehydroxylative cross-coupling of alcohols with phenols: rapid access to propofol derivatives DOI Creative Commons

Yuqiu Liang,

Chengxiu Liu,

Youchun Li

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(37), P. 26857 - 26862

Published: Jan. 1, 2024

Wide substrate scope (up to 43 examples); excellent regioselectivity with only para -alkylated product; simple reaction conditions TsOH as catalyst, high efficiency in yield; using stable and low toxicity alcohols alkylate.

Language: Английский

Citations

2
Iridium-catalyzed selective para-C-alkylation of anilines/phenols with aryl alkynes DOI
Renshi Luo,

Yuqiu Liang,

Sen Wang

et al.

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 428, P. 115184 - 115184

Published: Nov. 5, 2023

Language: Английский

Citations

4
Ir-Catalyzed Selective Reductive N-Formylation and Transfer Hydrogenation of N-Heteroarenes DOI
Renshi Luo, Sen Wang,

Yuqiu Liang

et al.

Organometallics, Journal Year: 2024, Volume and Issue: 43(18), P. 2097 - 2103

Published: Sept. 3, 2024

Selective functionalization has numerous potential applications in the modification of bioactive compounds and pharmaceuticals. Herein, we advance a new approach for selective reductive N-formylation N-heteroarenes transfer hydrogenation using IrIII complexes as catalysts. The combination solvent, equivalent formic acid (FA), reaction temperature, iridium catalyst exerts high product selectivity, delivering divergent formations products excellent yields. In this process, FA can be employed not only hydrogen source but also reagent under different conditions.

Language: Английский

Citations

1
Successive Hydrolysis and Transfer Hydrogenation of 2-Chloroquinolines to 3,4-Dihydroquinolones DOI
Renshi Luo, Sen Wang,

Yuqiu Liang

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(41), P. 17700 - 17705

Published: Jan. 1, 2024

A practical and efficient platform for the synthesis of 3,4-dihydroquinolones through successive hydrolysis transfer hydrogenation was presented. wide range 2-chloroquinolines were compatible with this catalytic system in excellent yields.

Language: Английский

Citations

1
Iridium-catalyzed reductive sulfonamidation of alkoxy aryl alkynes DOI Creative Commons

Yuqiu Liang,

Chengxiu Liu,

Ping Wei

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(51), P. 38146 - 38152

Published: Jan. 1, 2024

A novel reductive sulfonamidation of alkynes with primary and secondary sulfonamides using Cp*Ir catalyst, which provides inspiration for the synthesis diversified in good efficiency mild reaction conditions.

Language: Английский

Citations

0
Chemoselective Reductive Coupling of Α, Β-Unsaturated Esters and Nitroarenes for Sustainable Synthesis of Β-Amino Acid Esters by a Hierarchically Porous Cobalt Nanocatalyst DOI
Min Zhang, Huanhuan Jia,

Junwei Xi

et al.

Published: Jan. 1, 2023

Reductive coupling of two unsaturated substances for the construction functional molecules remains a significant challenge due to difficulty in controlling chemoselective reduction. Here, by developing cobalt and nitrogen co-doped hierarchically porous carbon material (Co/N-HPNC) deriving from homomorphic Zr-based metal-organic framework (MOF), we describe, first time, its application as bifunctional catalyst direct access β-amino acid esters via reductive hydroamination α, β-unsaturated with cheap air-stable nitroarenes. The structure-performance relationship reveals that N-dopants benefit adsorption nitroarenes protons, active species run transfer hydrogenation nitroarenes, such synergisitc effect results formation desired products. developed catalytic transformation proceeds good substrate functionality tolerance, use easily accessible reusable base metal catalyst, operational simplicity, high step atom efficiency, easy applicability further fabrication molecules, which offers sustainable platform synthesis valuable products bulk raw materials.

Language: Английский

Citations

0
Chemoselective reductive coupling of α, β-unsaturated esters and nitroarenes for sustainable synthesis of β-amino acid esters by a hierarchically porous cobalt nanocatalyst DOI
Huanhuan Jia,

Junwei Xi,

Rong Xie

et al.

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 429, P. 115239 - 115239

Published: Dec. 5, 2023

Language: Английский

Citations

0