Antibacterial Nanomaterials: Mechanisms, Impacts on Antimicrobial Resistance and Design Principles

Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(17)

Published: Jan. 31, 2023

Antimicrobial resistance (AMR) is one of the biggest threats to environment and health. AMR rapidly invalidates conventional antibiotics, antimicrobial nanomaterials have been increasingly explored as alternatives. Interestingly, several show AMR-independent effects without detectable new therefore suggested prevent evolution. In contrast, some are found trigger evolution AMR. Given these seemingly conflicting findings, a timely discussion two faces urgently needed. This review systematically compares killing mechanisms structure-activity relationships antibiotics nanomaterials. We then focus on nano-microbe interactions elucidate impacts molecular initiating events Finally, we provide an outlook future propose design principles for prevention

Language: Английский

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Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing

Advanced Drug Delivery Reviews, Journal Year: 2022, Volume and Issue: 193, P. 114670 - 114670

Published: Dec. 17, 2022

Language: Английский

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MXene and Polymer Collision: Sparking the Future of High‐Performance Multifunctional Coatings

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 8, 2024

Abstract The development of nanomaterials is crucial to upgrading modern industry. MXene nanosheets have attracted significant attention due their superb resistance permeation, diverse surface chemical properties, impressive mechanical and metal‐like electrical thermal conductivity, etc., providing unique advantages in various technical fields. When are combined with polymers form functional coatings, applications span multiple fields, including anticorrosion, wear resistance, flame‐retardancy, electromagnetic interference (EMI) shielding, de‐icing. This review, conjunction MXene's barrier property, lubricity, stability, photothermal conversion discusses detail the MXene‐based polymer coatings. Additionally, it examines dispersion interaction within coatings role functionalized polymers. Finally, based on current research status emerging needs, challenges future opportunities a targeted manner discussed. review aims summarize existing results put forward an objective fair point view, constructive reference for nanofunctional

Language: Английский

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MXenes: Versatile 2D materials with tailored surface chemistry and diverse applications

Journal of Energy Chemistry, Journal Year: 2023, Volume and Issue: 90, P. 253 - 293

Published: Dec. 5, 2023

Language: Английский

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Emerging 2D MXenes for antibacterial applications: Current status, challenges, and prospects

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 492, P. 215275 - 215275

Published: June 7, 2023

Language: Английский

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Multifunctional electromagnetic wave absorbing carbon fiber/Ti3C2TX MXene fabric with superior near-infrared laser dependent photothermal antibacterial behaviors

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 676, P. 217 - 226

Published: July 14, 2024

Language: Английский

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A multifunctional cascade nanoreactor based on Fe-driven carbon nanozymes for synergistic photothermal/chemodynamic antibacterial therapy

Acta Biomaterialia, Journal Year: 2023, Volume and Issue: 168, P. 580 - 592

Published: July 13, 2023

Language: Английский

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Nanomaterials-based advanced systems for photothermal / photodynamic therapy of oral cancer

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 272, P. 116508 - 116508

Published: May 15, 2024

Language: Английский

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Unveiling the potential of HKUST-1: synthesis, activation, advantages and biomedical applications

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(11), P. 2670 - 2690

Published: Jan. 1, 2024

HKUST-1 represents a promising biomaterial, functioning not only as drug carrier but also releasing bioactive copper ions, thereby demonstrating exceptional antitumor, antibacterial, and wound healing properties.

Language: Английский

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Enhanced Biological Behavior and Photothermal Antibacterial Performance of TiNbCT_x MXene Modified Mesoporous Bioactive Glass Nanocomposites

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Abstract Mesoporous bioactive glasses (MBGs) are gaining recognition in bone tissue engineering for their osteoblast differentiation‐inducing properties and customizable structures. However, the challenge of peri‐implantitis has hindered broader application. To address this, double transition metal TiNbCT x MXene acted as near‐infrared (NIR) photothermal agent, been integrated with MBG nanospheres to develop novel multifunctional /MBG (TNC/MBG) nanocomposites this work. The results demonstrate that TNC/MBG composites feature uniform mesoporous spherical nanoparticles on nanosheets, boasting a significantly enhanced specific surface area up 444.74 m 2 g −1 more negative zeta potential than pristine MBG. Importantly, can effectively promote apatite formation, well proliferation viability MC3T3‐E1 cells. Moreover, it is highlighted display remarkable conversion efficiency stability, leading over 95% antibacterial inhibition rates against both S. aureus E. coli under NIR irradiation. These findings offer an appealing strategy biological activity robust properties, which shows great various biomedical applications.

Language: Английский

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