Open Veterinary Journal,
Journal Year:
2024,
Volume and Issue:
14(6), P. 1358 - 1358
Published: Jan. 1, 2024
Healing
of
bum
wounds
is
commonly
associated
with
many
complications.
Every
year
various
new
repair
materials
are
developed
and
experimentally
used
for
treating
burn
wounds.
Humans
diabetes
mellitus
usually
suffer
from
chronic
wound
healing.
Vascular,
neuropathic,
immune
function,
biochemical
abnormalities
each
contribute
to
the
altered
tissue
repair.
One
underlying
factor
that
accompanies
all
diabetic
ulcerations
poor
vascular
flow,
a
circumstance
impedes
proper
Numerous
studies
have
highlighted
importance
adequate
sufficiency
vessel
proliferation
in
lack
thereof
Other
looked
at
whether
disarrayed
capillary
remodeling
maturation
vessels
might
play
role
impaired
Journal of Tissue Engineering,
Journal Year:
2024,
Volume and Issue:
15
Published: Jan. 1, 2024
The
rising
prevalence
of
diabetes
has
underscored
concerns
surrounding
diabetic
wounds
and
their
potential
to
induce
disability.
intricate
healing
mechanisms
are
multifaceted,
influenced
by
ambient
microenvironment,
including
prolonged
hyperglycemia,
severe
infection,
inflammation,
elevated
levels
reactive
oxygen
species
(ROS),
ischemia,
impaired
vascularization,
altered
wound
physicochemical
properties.
In
recent
years,
hydrogels
have
emerged
as
promising
candidates
for
treatment
owing
exceptional
biocompatibility
resemblance
the
extracellular
matrix
(ECM)
through
a
three-dimensional
(3D)
porous
network.
This
review
will
first
summarize
microenvironment
alterations
occurring
in
wounds,
aiming
provide
comprehensive
understanding
its
pathogenesis,
then
classification
recently
developed
be
presented,
encompassing
properties
such
hypoglycemic
effects,
anti-inflammatory
capabilities,
antibacterial
attributes,
ROS
scavenging
abilities,
promotion
angiogenesis,
pH
responsiveness,
more.
primary
objective
is
offer
valuable
reference
repairing
based
on
unique
microenvironment.
Moreover,
this
paper
outlines
avenues
future
advancements
hydrogel
dressings
facilitate
expedite
process
wounds.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2024,
Volume and Issue:
12(20), P. 7757 - 7766
Published: May 10, 2024
Photoluminescent
hydrogels
show
great
potential
in
the
fields
of
information
storage
and
security,
environmental
monitoring
protection,
vivo
noninvasive
monitoring,
drug
delivery,
tissue
engineering.
Current
fluorescent
are
prepared
by
coupling
or
doping
units,
such
as
semiconductor
quantum
dots,
metal–ligand
complexes,
lanthanide
ions,
organic
dyes,
into
polymer
hydrogel
matrices.
However,
conventional
have
intrinsic
defects,
including
poor
photostability,
toxicity,
low
mechanical
strength,
which
severely
limit
their
applications.
In
this
study,
we
developed
an
intrinsically
photoluminescent
dual-network
with
excellent
properties.
Poly(vinyl
alcohol)
formed
first
network,
aminopolysiloxane
citric
acid
forming
second
(APSi
network)
via
amidation-cross-linking
chemistry.
The
introduction
APSi
network
endowed
photoluminescence
enhanced
properties,
can
be
adjusted
changing
APSi-network
content.
innovatively
possesses
photoluminescence,
light
stability,
tunable
is
highly
biocompatible,
highlights
its
applicability
many
fields.
This
study
provides
a
simple
versatile
strategy
for
preparing
novel
multidisciplinary
application
potential.
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
Natural
jellyfish
collagen
(JC)
has
garnered
significant
attention
in
the
field
of
hemostasis
due
to
its
oceanic
origin,
nontoxicity,
biodegradability,
and
absence
complications
related
diseases
religious
beliefs.
However,
hemostatic
performance
pure
JC
is
limited
by
poor
stability,
adhesion
wet
tissue,
mechanical
properties.
We
developed
a
novel
(HJP)
sponge
comprising
JC,
protocatechuic
acid
(PA),
hydroxybutyl
chitosan
(HS)
enhance
application
emergency
hemostasis.
This
exhibits
antibacterial
properties,
good
biocompatibility,
tissue
adhesion,
capabilities.
The
HJP
demonstrates
excellent
thermal
stability
strength
(tensile
strength:
∼106.6
kPa,
compressive
at
70%
strain:
∼1013.5
kPa)
strong
(∼117.1
kPa).
Upon
wound,
rapidly
forms
wound
seal,
achieving
effective
through
synergistic
action
PA
JC.
blood
loss
was
also
reduced
0.105
g
when
compared
commercial
gelatin
sponge.
JC-based
sponge,
with
multifaceted
characteristics,
holds
promise
for
rapid
clinical
applications.
ACS Applied Polymer Materials,
Journal Year:
2024,
Volume and Issue:
6(13), P. 7572 - 7583
Published: June 21, 2024
An
injectable
hydrogel
loading
α-N-heterocyclic
thiosemicarbazones
with
antibacterial
activity
was
designed
to
attain
therapy
against
wounds
high
efficiency.
In
the
present
study,
FPZ-H2L
synthesized
by
2,6-diacetylpyridine
bis(N4-methylthiosemicarbazone)
(H2L)
on
transition-metal
ions
(Zn2+)-cross-linked-folic
acid
(FA)-co-polydopamine
(PDA)
(FPZ
hydrogel).
The
(FPZ-H2L)
cross-linked
coordination
and
hydrogen
bonds
displayed
an
excellent
self-healing
performance
completely
covered
irregular
wound.
Compared
FPZ
hydrogel,
has
stronger
efficacy
typical
Gram-positive/negative
bacteria
drug-resistant
bacteria.
mechanisms
of
were
related
biofilm
ablation,
disruption
cell
membrane
integrity,
leakage
nucleic
acids
proteins,
production
oxidative
stress
response,
thus
causing
bacterial
death.
Cell
Counting
Kit-8
(CCK-8)
test
shows
that
compatibility,
gel
drug
technology
greatly
overcomes
problem
cytotoxicity
H2L.
wound
healing
experiments
indicated
enhanced
mice.
These
results
prove
mixed
broadened
field
vision
for
design
dressings.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(9), P. 1171 - 1171
Published: Sept. 5, 2024
Although
various
chemically
synthesized
materials
are
essential
in
medicine,
food,
and
agriculture,
they
can
exert
unexpected
side
effects
on
the
environment
human
health
by
releasing
certain
toxic
chemicals.
Therefore,
eco-friendly
biocompatible
biomaterials
based
natural
resources
being
actively
explored.
Recently,
biosilica
derived
from
diatoms
has
attracted
attention
biomedical
fields,
including
drug
delivery
systems
(DDS),
due
to
its
uniform
porous
nano-pattern,
hierarchical
structure,
abundant
silanol
functional
groups.
Importantly,
structural
characteristics
of
diatom
improve
solubility
poorly
soluble
substances
enable
sustained
release
loaded
drugs.
Additionally,
predominantly
comprises
SiO
