Published: Jan. 1, 2024
Language: Английский
Journal of Cardiovascular Magnetic Resonance, Journal Year: 2025, Volume and Issue: unknown, P. 101853 - 101853
Published: Feb. 1, 2025
Quantitative assessment of morphological and functional cardiac parameters by cardiovascular magnetic resonance (CMR) is essential for research routine clinical practice. Beyond established chamber size function, tissue properties such as relaxation times play an increasing role. Normal reference ranges are required interpretation results obtained quantitative CMR. Since the last publication "normal value review" in 2020 many new publications related to CMR values have been published, which were integrated this update. The larger sample provides greater statistical confidence estimates upper lower limits, enables further partitioning, e.g., age ethnicity several parameters. Previous topics expanded sections.
Language: Английский
Citations
1
Journal of the American College of Cardiology, Journal Year: 2024, Volume and Issue: 83(16), P. 1614 - 1618
Published: April 1, 2024
Language: Английский
Citations
4
Russian Journal of Preventive Medicine, Journal Year: 2025, Volume and Issue: 28(1), P. 89 - 89
Published: Jan. 1, 2025
Language: Английский
Citations
0
Archives of Gerontology and Geriatrics, Journal Year: 2025, Volume and Issue: 131, P. 105777 - 105777
Published: Feb. 3, 2025
The prevention and management of degenerative heart disease remain challenging could potentially be significantly improved by understanding ageing biomarker dynamics. In this study, we constructed the calcific aortic valve mouse model at different age points, measured function degeneration along with calcification, investigated nonlinear dynamics using sequencing data deep learning models. C57BL/6 N model, older mice had higher levels peak transvalvular jet velocity in terms function. Regarding collagen elastic fiber calcification middle layer increased 48-week-old (p < 0.001), spread to inner endothelial cells 72-week-old 0.0001). RNA illustrated that 30 genes, including Acadsb, L2hgdh, Cpped1, showed expression age. Among them, four namely Hipk2, 9430069I07Rik, Peli3, Slc22a12, more than threefold tissues compared 6-week-old mice. Moreover, a large proportion genes changed pattern (6,325 out 12,160, 52%). conclusion, both linear gero-markers were found modeling, which highlighted specific periods significant wave accelerated (48-week-old mice).
Language: Английский
Citations
0
Preventive Medicine Reports, Journal Year: 2025, Volume and Issue: 51, P. 102997 - 102997
Published: Feb. 7, 2025
This study aimed to estimate and compare cardiometabolic disease (CMD) mortality in U.S. Black White men during the transition from early adulthood middle age. Using 2022 National Vital Statistics System data standard period life table methods, we estimated risk of CMD death hypothetical cohorts age 25 45 years. We cumulative risk, excess mortality, years lost (YLL), proportion deaths due CMD, stratifying by metabolic cardiovascular disease. Of 325,134 aged initial cohort, before was one 63 individuals or 1.58 %. For men, risks were markedly lower. 1,185,384 158 0.63 The also found that 5141 expected 3090 60.10 % relative cohort. Additionally, all among 19.15 rising 6.02 at 38.00 45, compared with 11.10 increasing 4.57 19.79 45. YLL for averaged 6.72 months per person while 2.94 months. investigation shows profound racial disparities mid-adulthood.
Language: Английский
Citations
0
European Heart Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 29, 2025
Abstract As life expectancy continues to increase due advancements in medical technology, public health, nutrition, and socioeconomic progress, the population of older adults USA Europe is rapidly growing. By 2050, individuals aged 65 are projected constitute over 20% US 29% European population, leading a higher prevalence chronic diseases, including cardiovascular disease. Cardiovascular disease, cause death USA, poses significant challenges healthy ageing by contributing accelerated biological development geriatric syndromes. This state-of-the-art review aims (i) define for patients living with disease; (ii) compare chronological vs as it pertains (iii) describe impact syndromes provide an approach management prevention; (iv) address gaps knowledge future directions potential interventions that could promote ageing.
Language: Английский
Citations
0
European Heart Journal Open, Journal Year: 2025, Volume and Issue: 5(3)
Published: April 30, 2025
Abstract Aims Cardiac ageing involves a series of anatomical and physiological changes contributing to decline in overall performance. magnetic resonance (CMR) provides comprehensive structural functional assessment for detecting age-related cardiovascular remodelling. We aimed develop fully automated CMR model predict heart age. Methods results This international, multi-centre, retrospective observational study enrolled 191 healthy individuals with normal body mass index (BMI), free metabolic, cardiovascular, respiratory disease as the derivation cohort. Left atrial (LA) end-systolic volume LA ejection fraction were selected final model. The was validated on 366 patients BMI >25 kg/m2 one or more comorbidities [hypertension, diabetes mellitus (DM), fibrillation (AF), obesity]. In [median age: 34 years, 105 (55%) female], CMR-derived age similar chronological [bias: 0.05%, 95% confidence interval (CI): 9.56–9.67%, P = 0.993]. validation cohort 53 157 (43%) 4.6 years higher than (95% CI: 1.6–7.6 0.003). resonance-derived significantly hypertension (P < 0.001), DM AF 0.001) age-matched controls. Moreover, obesity Class I 0.07), II 0.11), III 0.001). Conclusion highlights time course during unhealthy ageing. propose simple equations that should help communicate subtle Registration ClinicalTrials.gov: NCT05114785
Language: Английский
Citations
0
Circulation Cardiovascular Imaging, Journal Year: 2024, Volume and Issue: 17(7)
Published: July 1, 2024
Language: Английский
Citations
0
Diagnostics, Journal Year: 2024, Volume and Issue: 14(17), P. 1947 - 1947
Published: Sept. 3, 2024
Aging affects the cardiovascular system, and this process may be accelerated in individuals with risk factors. The main vascular changes include arterial wall thickening, calcification, stiffening, together aortic dilatation elongation. With aging, we can observe left ventricular hypertrophy myocardial fibrosis atrial dilatation. These lead to heart failure fibrillation. Using multimodality imaging, including ultrasound, computed tomography (CT), magnetic resonance it is possible detect these changes. Additionally, mainly via CT measurements of coronary artery calcium or ultrasound carotid intima-media thickness, enables advanced stratification helps decision-making about preventive strategies. focus manuscript briefly review that occur as well describe how imaging used for assessment asymptomatic individuals.
Language: Английский
Citations
0
Published: Jan. 1, 2024
Language: Английский
Citations
0