Chitosan nanoparticles of imatinib mesylate coated with TPGS for the treatment of colon cancer: In-vivo & in-vitro studies DOI
Darshan Bhirud, Sankha Bhattacharya, Harshvardhan Raval

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 348, P. 122935 - 122935

Published: Nov. 4, 2024

Language: Английский

Future Prospects of Natural Polymer-Based Drug Delivery Systems in Combating Lung Diseases DOI
Saman Yasamineh, Omid Gholizadeh, Hesam Ghafouri Kalajahi

et al.

Published: Jan. 1, 2023

Natural polymers have been widely studied as the carriers for transfer of medications and different therapeutic molecules, which attracted significant attention. polymers' inherent benefits in extraordinary biocompatibility, controlled enzyme degradation, particular interactions with several biomolecules, simple modification endow them versatility drug delivery. In lung diseases, using natural delivery methods can enhance effectiveness drugs because their associated sustained discharge, targeting efficacy, patient compliance. this context, explored to match demand, including chitosan, polysaccharides, alginate, gelatin. Moreover, system produced by polymer derivatives has offered focus on chemical morphological alterations, decorations smart stimuli-responsive or targeted motifs, so on, improved treatment effectiveness. More intelligent approaches developed, more multifunctional polymer-based are used future. This chapter contains progressions that cancer respiratory diseases. The section at end also shows future systems combating

Language: Английский

Citations

12

Marine biomaterials in biomedical nano/micro-systems DOI Creative Commons
Yanan Wang, Long Chen,

Yuanzheng Wang

et al.

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Nov. 5, 2023

Abstract Marine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and biological activities compared to terrestrial species. These marine-derived raw materials, including polysaccharides, protein components, fatty acids, minerals, etc., have shown great potential preparing, stabilizing, or modifying multifunctional nano-/micro-systems are widely applied drug delivery, theragnostic, tissue engineering, etc. This review provides a comprehensive summary of the most current biomaterial-based developed over past three years, primarily focusing on therapeutic delivery studies highlighting their cure variety diseases. Specifically, we first provided detailed introduction physicochemical characteristics biocomponents state. Furthermore, assembly processes, functionalities each building block, thorough evaluation pharmacokinetics pharmacodynamics advanced systems effects molecular pathophysiological processes were fully elucidated. Finally, list unresolved issues pivotal challenges applications, such as standardized distinction long-term biosafety vivo, feasibility scale-up, was presented. is expected serve roadmap for fundamental research facilitate rational design diverse emerging applications. Graphical

Language: Английский

Citations

12

Red blood cells in biology and translational medicine: natural vehicle inspires new biomedical applications DOI Creative Commons
Xueyun Zhang,

Yindan Lin,

Jinxia Xin

et al.

Theranostics, Journal Year: 2023, Volume and Issue: 14(1), P. 220 - 248

Published: Nov. 15, 2023

Red blood cells (RBCs) are the most abundant cell type in blood, and play a critical role oxygen transport.With development of nanobiotechnology synthetic biology, scientists have found multiple ways to take advantage characteristics RBCs, such as their long circulation time, construct universal develop drug delivery systems, transform therapies for cancer other diseases.This article reviews component aging mystery methods applied application prospects engineering modification RBCs used cytopharmaceuticals immunotherapy.Finally, we summarize some perspectives on biological features provide further insights into translational medicine.

Language: Английский

Citations

12

Nanocarrier-based drug delivery via cell-hitchhiking: Emphasizing pharmacokinetic perspective towards taming the “big-old” tumors DOI

Paras Famta,

Saurabh Shah,

Naitik Jain

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 89, P. 105050 - 105050

Published: Oct. 7, 2023

Language: Английский

Citations

11

Chitosan nanoparticles of imatinib mesylate coated with TPGS for the treatment of colon cancer: In-vivo & in-vitro studies DOI
Darshan Bhirud, Sankha Bhattacharya, Harshvardhan Raval

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 348, P. 122935 - 122935

Published: Nov. 4, 2024

Language: Английский

Citations

4