Influence of melatonin on the development of obesity DOI Creative Commons
A. V. Yusupov,

V. A. Likhodkin

Новые Санкт-Петербургские врачебные ведомости., Journal Year: 2024, Volume and Issue: 2, P. 25 - 33

Published: Nov. 1, 2024

In recent years, increasing attention of researchers has been paid to the role melatonin in regulation body weight. When analyzing literature data, problem mechanism action on and its use correction metabolic disorders is considered. Disruption circadian rhythms caused by artificial light at night leads decreased secretion. This helps increase appetite reduce energy costs. addition, plays a major modulating secretion adipokines influencing lipid metabolism. Decreased production causes insulin resistance disorganization, leading obesity. Assessing development obesity accompanying pathologies promising area scientific research field diagnosis, prevention treatment endocrine cardiovascular pathologies.

Language: Английский

Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis DOI
Fengjuan Li, Miyesaier Abudureyimu,

Zeng-Hui Zhang

et al.

Chemico-Biological Interactions, Journal Year: 2024, Volume and Issue: 398, P. 111104 - 111104

Published: June 19, 2024

Language: Английский

Citations

10
The Association Between the Triglyceride–Glucose Index, Its Combination with the Body Roundness Index, and Chronic Kidney Disease in Patients with Type 2 Diabetes in Eastern China: A Preliminary Study DOI Open Access
Xiangyu Chen,

Xiaofu Du,

Feng Lü

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 492 - 492

Published: Jan. 29, 2025

Objectives: This study aimed to investigate the relationship between triglyceride–glucose (TyG) index, its combination with body roundness index (BRI), and chronic kidney disease (CKD) in patients type 2 diabetes mellitus (T2DM) based on a cross-sectional analysis conducted Eastern China. Methods: The research originates from performed Zhejiang Province, China, March November 2018. TyG-BRI was calculated triglyceride, fasting blood glucose, BRI. correlation risk of CKD assessed using restricted cubic spline model. A multivariate logistic regression model used association CKD. Receiver operating characteristic (ROC) analyses evaluate optimal cut-off value for predicting Results: total 1756 T2DM participants were enrolled this study. significantly higher than those without In fully adjusted model, odds ratios second, third, fourth quartiles 0.93 (95% CI: 0.65–1.33), 1.33 0.94–1.88), 1.57 1.10–2.25), respectively, compared first quartile. RCS confirmed linear dose–response (all p nonlinearity > 0.05). ROC curve revealed that had moderate predictive CKD, an area under 0.626 0.597–0.656, < 0.001). 42.46, sensitivity 68.2% specificity 52.2%. Conclusions: positively associated population, demonstrating value. It may serve as valuable tool identifying high-risk individuals informing targeted interventions prevent or delay progression population.

Language: Английский

Citations

1
The Kidney in Obesity: Current Evidence, Perspectives and Controversies DOI
Dimitris Kounatidis, Natalia G. Vallianou, Theodora Stratigou

et al.

Current Obesity Reports, Journal Year: 2024, Volume and Issue: 13(4), P. 680 - 702

Published: Aug. 14, 2024

Language: Английский

Citations

7
The Perceptions of and Attitudes Toward Obesity in Bulgarian Adults with a BMI ≥ 25.0 kg/m2—An Exploratory Study DOI Open Access
Mihail Boyanov,

Margarita Boeva Grigorova,

Anna Todorova Karteva-Stoycheva

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 373 - 373

Published: Jan. 21, 2025

Background: Obesity affects 33.2% of the adult population in Bulgaria, and there is a scarcity information about affected individuals’ attitudes toward their weight situation. The aim this study was to explore perceptions obesity adults. Methods: present involved questionnaire-based survey that utilized home-based tablet-assisted face-to-face interviews. Interviewees comprised individuals aged 25–64 y/o with BMI > 25.0 kg/m2. Results: Overall, 704 respondents participated (344 overweight; 360 obese). Over 50% participants reported attempts reduce weight, only 6% overweight group 16% obese perceiving condition as worrisome. One-third considered state temporary. main cause for alarm overweight/obese worsening overall physical males an increase clothes size females. need urgent reduction body noted by 12% 40% respondents. reasons being were collated lack activity (noted 52% participants), sedentary lifestyle (51%), stress/depression (41%), excessive consumption carbohydrates (34%), general overconsumption food (33%), poor quality products (28%). Of note, 56% had first consulted medical professional overweight. Most selected dieting without reduction, 48% stating they would try drugs approved reduction. Conclusions: Many have unrealistic self-perception very low motivation take active measures. These discrepancies offer great opportunities better public education structured, strategies.

Language: Английский

Citations

0
Chronic kidney disease awareness: a cross-sectional study in primary care settings in Türkiye DOI Creative Commons
Esra Gök, Mustafa Kürşat Şahin

Journal of Nephrology, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Abstract Background Raising awareness of chronic kidney disease (CKD) is essential for early detection and prevention, since the condition remains largely underdiagnosed, particularly in primary care settings. The present study aimed to evaluate levels regarding causes symptoms CKD among individuals receiving care. Methods This cross-sectional included 457 participants recruited from two centers Türkiye using systematic random sampling. data were collected via face-to-face interviews a pre-tested questionnaire between April June 2023. Awareness classified Bloom’s cutoff points–high (≥ 80%), moderate (60–79%), low (< 60%). Results mean age was 42.3 ± 14.9 years. population consisted 55.4% women, 51.2% aged 18–39, 74.6% married, 53.4% held at least university bachelor’s degree. As awareness, 64.1% aware that can be caused by pain medication, 56% it hypertension, 48.8% result diabetes. Additionally, 58.6% swelling feet ankles represent symptom CKD. 78.6% our (n = 359), 17.5% ( n 80) high 3.9% 18). Individuals who recalled having been informed about these their physicians exhibited higher awareness. No significant differences observed across different sociodemographic groups. A positive correlation its symptoms. Conclusions limited, nearly half being unaware key risk factors such as painkiller use, obesity, smoking, diabetes, herbal product use. Increased education, physicians, may improve rates. Graphical abstract

Language: Английский

Citations

0
Performance of Current Chronic Kidney Disease Screening Criteria in Women and Men Across Ethnic Groups: The HELIUS Study DOI
Taryn G. Vosters, Vianda S Stel, Kitty J. Jager

et al.

Mayo Clinic Proceedings Innovations Quality & Outcomes, Journal Year: 2025, Volume and Issue: 9(3), P. 100613 - 100613

Published: April 17, 2025

Language: Английский

Citations

0
Multifrequency Low-level Laser-Assisted Lipolysis Outcomes. A Dataset from 101 patients DOI Creative Commons
Gabriel Cubillos-Valencia, N. Vasquez, Andrés Miguel Ortegón Pulido

et al.

Data in Brief, Journal Year: 2024, Volume and Issue: 57, P. 111038 - 111038

Published: Oct. 18, 2024

Language: Английский

Citations

0
Influence of melatonin on the development of obesity DOI Creative Commons
A. V. Yusupov,

V. A. Likhodkin

Новые Санкт-Петербургские врачебные ведомости., Journal Year: 2024, Volume and Issue: 2, P. 25 - 33

Published: Nov. 1, 2024

In recent years, increasing attention of researchers has been paid to the role melatonin in regulation body weight. When analyzing literature data, problem mechanism action on and its use correction metabolic disorders is considered. Disruption circadian rhythms caused by artificial light at night leads decreased secretion. This helps increase appetite reduce energy costs. addition, plays a major modulating secretion adipokines influencing lipid metabolism. Decreased production causes insulin resistance disorganization, leading obesity. Assessing development obesity accompanying pathologies promising area scientific research field diagnosis, prevention treatment endocrine cardiovascular pathologies.

Language: Английский

Citations

0