Deleted Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
The
chemical
modification
of
polymers
is
essential
for
enhancing
their
properties
and
broadening
applications,
particularly
in
drug
delivery
systems.
This
study
aims
to
provide
a
comprehensive
overview
polymer
by
exploring
various
techniques
surface,
bulk,
post-synthetic
changes.
A
literature
review
analysis
existing
methodologies
reveal
how
these
modifications
influence
industrial,
biomedical,
environmental
with
specific
focus
on
tissue
engineering.
Key
findings
demonstrate
significant
improvements
encapsulation
efficiency,
controlled
release
kinetics,
biocompatibility,
statistical
analyses
confirming
enhancements.
Despite
advancements,
challenges
such
as
high
production
costs,
impacts,
stability
issues
persist.
concludes
outlining
future
directions
research,
emphasizing
the
importance
innovative
methods,
advanced
techniques,
creation
sustainable
address
limitations
enhance
performance
field.
Asian Journal of Pharmaceutical Sciences,
Journal Year:
2023,
Volume and Issue:
18(3), P. 100812 - 100812
Published: April 27, 2023
Biopolymers
are
promising
environmentally
benign
materials
applicable
in
multifarious
applications.
They
especially
favorable
implantable
biomedical
devices
thanks
to
their
excellent
unique
properties,
including
bioactivity,
renewability,
bioresorbability,
biocompatibility,
biodegradability
and
hydrophilicity.
Additive
manufacturing
(AM)
is
a
flexible
intricate
technology,
which
widely
used
fabricate
biopolymer-based
customized
products
structures
for
advanced
healthcare
systems.
Three-dimensional
(3D)
printing
of
these
sustainable
applied
functional
clinical
settings
wound
dressing,
drug
delivery
systems,
medical
implants
tissue
engineering.
The
present
review
highlights
recent
advancements
different
types
biopolymers,
such
as
proteins
polysaccharides,
employed
develop
by
using
extrusion,
vat
polymerization,
laser
inkjet
3D
techniques
addition
normal
bioprinting
four-dimensional
(4D)
techniques.
This
also
incorporates
the
influence
nanoparticles
on
biological
mechanical
performances
3D-printed
scaffolds.
work
addresses
current
challenges
well
future
developments
friendly
polymeric
manufactured
through
AM
Ideally,
there
need
more
focused
research
adequate
blending
biodegradable
biopolymers
achieving
useful
results
targeted
areas.
We
envision
that
composites
have
potential
revolutionize
sector
near
future.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(16), P. 18458 - 18468
Published: April 15, 2024
Imbalances
in
hemoglobin
(Hb)
levels
can
lead
to
conditions
such
as
anemia
or
polycythemia,
emphasizing
the
importance
of
precise
Hb
extraction
from
blood.
To
address
this,
a
novel
synthetic
imprinted
polymer
was
meticulously
developed
for
capturing
and
separating
Hb.
Poly(acrylamide-vinylimidazole)
nanopolymer
(poly(AAm-VIM))
synthesized
using
acrylamide
vinyl
imidazole
functional
monomers
through
surfactant-free
emulsion
polymerization.
Characterization
FTIR,
particle
size,
zeta
potential,
SEM
ensured
polymer's
structure.
The
Hb-imprinted
(Hb-poly(AAm-VIM))
demonstrated
notable
specificity,
with
calculated
Hb-specific
adsorption
value
(Qmax)
3.7377
mg/g
medium
containing
2.5
mg/mL
molecularly
(MIP)
exhibited
approximately
5
times
higher
than
nonimprinted
(NIP).
Under
same
conditions,
displayed
2.39
2.17
greater
selectivity
over
competing
proteins
bovine
serum
albumin
(BSA)
lysozyme
(Lys),
respectively.
Also,
SDS-PAGE
analysis
results
confirmed
purification
by
nanopolymer.
These
underscore
heightened
specificity
efficacy
selectively
targeting
atoms
among
other
proteins.
Incorporating
polymers
is
justified
their
affinity,
cost-effectiveness,
facile
production.
This
research
contributes
valuable
insights
into
optimizing
efficient
extraction,
potential
medical
diagnostics
treatment
applications.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(9), P. 3689 - 3689
Published: April 25, 2023
Biopolymers
such
as
chitosan
(CHT)
or
alginate
(ALG)
are
among
the
most
prominent
for
health-related
applications
due
to
their
broad
bioactivity.
Their
combination
preparation
of
membranes
is
hereby
proposed
an
application
wound
healing
with
incorporation
lavender
essential
oil
(LEO),
widely
known
its
antioxidant
and
antimicrobial
properties.
The
CHT,
CHT
+
LEO,
ALG,
ALG
CHT/ALG
LEO
was
accomplished,
composition
analyzed
using
Fourier
Transform
Infrared
Spectroscopy
(FTIR).
water
absorption
capacity
release
profile
revealed
higher
uptake
when
a
lower
obtained.
combined
film
showed
percentage
638%
after
48
h
maximum
concentration
42
mg/L.
Cytotoxicity
biocompatibility
prepared
were
studied
HaCaT
cell
line,
assessment
viability
regarding
leachables,
DNA
quantification,
DAPI-phalloidin
staining.
results
that
indirect
contact
via
leachables
does
not
compromise
viability,
upon
direct
contact,
cells
do
adhere
proliferate
on
surface
membranes.
Moreover,
membrane
increases
proliferation,
making
it
suitable
in
healing.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(5), P. 558 - 558
Published: Feb. 20, 2025
(1)
Background:
This
review
study
will
delve
into
the
potential
of
chitosan
nanoparticles
(NPs)
as
adaptable
carriers
for
targeted
drug
delivery
in
different
therapeutic
areas.
Chitosan
is
a
biopolymer
derived
from
chitin
that
has
attracted
interest
applications
because
its
high
biocompatibility
and
biodegradability.
(2)
Methods:
A
comprehensive
literature
was
conducted
by
following
careful
systematized
protocol
searching
databases
like
PubMed,
Google
Scholar
ScienceDirect.
(3)
Results:
NPs
are
good
vehicles,
notably
cancer.
Studies
reveal
doxorubicin-loaded
dramatically
enhance
toxicity
to
tumor
cells
compared
free
medicines,
yielding
suppression
rates
up
60%.
Researchers
found
chemotherapeutics
had
an
85%
encapsulation
efficiency
(EE),
lowering
systemic
toxicity.
Magnetic
pH-responsive
boost
accumulation
63%
apoptosis
54%.
also
boosts
medication
retention
lungs
2.3×,
per
pulmonary
trials.
ocular
bioavailability
3×
improve
nasal
absorption
30%,
crossing
blood-brain
barrier.
For
bone
regeneration,
scaffolds
mineral
density
46%,
facilitating
osteogenesis
healing.
(4)
Conclusions:
made
provide
solid
foundation
improving
systems;
yet
there
still
issues
with
material
variability,
scalability,
meeting
regulatory
requirements
need
fixing.
Research
combination
treatments,
ways
increase
their
specificity,
optimize
these
offers
promising
prospects
creation
novel
approaches
patient
outcomes.
Membranes,
Journal Year:
2024,
Volume and Issue:
14(1), P. 12 - 12
Published: Jan. 1, 2024
The
demand
for
natural
products
in
the
treatment
of
dermatological
pathologies
has
boosted
use
bioactive
substances
such
as
lavender
essential
oil
(LEO),
which
stands
out
its
anti-inflammatory
and
antioxidant
properties
antimicrobial
potential.
Biopolymers
chitosan
(CHT)
alginate
(ALG)
are
biodegradable
biocompatible
have
proven
their
viability
biomedical
applications
skin
regeneration.
inhibitory
effect
LEO
on
growth
skin-related
bacterial
species
Staphylococcus
aureus,
epidermidis,
Pseudomonas
aeruginosa
fungus
Candida
albicans
was
studied
by
incorporating
1%
v/v
encapsulated
CHT,
ALG,
CHT/ALG
membranes.
Despite
verification
all
type
membranes,
no
synergistic
observed
following
addition
LEO.
S.
aureus
P.
showed
most
different
substrates
C.
demonstrated
highest
inhibition.
This
is
a
first
approach
using
microorganisms
isolated
from
clinical
samples
or
microbiota.
Further
investigation
would
be
advisable
more
strains
each
microorganism
to
validate
applicability.
