Nano-scale drug delivery systems for carboplatin: A comprehensive review

OpenNano, Journal Year: 2023, Volume and Issue: 13, P. 100175 - 100175

Published: July 25, 2023

Language: Английский

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The effect of gibberellic acid on wheat growth and nutrient uptake under combined stress of cerium, zinc and titanium dioxide nanoparticles

Chemosphere, Journal Year: 2023, Volume and Issue: 336, P. 139199 - 139199

Published: June 12, 2023

Language: Английский

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Topical delivery of nanoemulsions for skin cancer treatment

Applied Materials Today, Journal Year: 2023, Volume and Issue: 35, P. 102001 - 102001

Published: Nov. 23, 2023

Skin cancer chemotherapeutics often lead to the development of severe cytotoxicity, compelling novel delivery systems not only enhance therapeutic efficacy but also minimize side effects and improve patient compliance. In recent years, topical nanoemulsions have emerged as powerful tools in field skin management. This review delves into potential these innovative formulations revolutionize treatment malignancies, due their unique properties, having relevant advantages, such allowing high drug strength, permeation retention enhancement, biocompatibility, controlled release capacity. Despite skin's formidable permeability challenges, it remains an accessible interface for carriers both locally (topical dermal) systemically (transdermal). Nanoemulsions, once associated primarily with cosmetic applications, are now gaining prominence essential components strategies. explores nanoemulsions, shedding light on ability efficiently deliver a wide range molecules, overcoming lipophilic barriers inherent skin. this comprehensive analysis several distinct studies investigating NEs treatment, diverse array were explored, revealing spectrum characteristics. The PDI spans from minimum 0.105 nm maximum 0.421 nm, reflecting variations droplet size distribution. Droplet sizes exhibit considerable diversity, ranging small 16 larger 200 signifying varied penetration. ZP values further contribute highly favorable (-66.6 mV) less advantageous or near zero values, indicative surface charge As healthcare costs continue escalate, nuanced overview nanoemulsion characteristics provides valuable insights applications targeted melanoma and, lesser extent, non-melanoma cancers. value safer becomes increasingly evident. Here, we focus exclusively role advancing therapy.

Language: Английский

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Customizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Oct. 13, 2023

Anaplastic thyroid cancer (ATC) is a rare but highly aggressive kind of cancer. Various therapeutic methods have been considered for the treatment ATC, its prognosis remains poor. With advent nanomedicine era, use nanotechnology has introduced in various cancers and shown great potential broad prospects ATC treatment. The current review meticulously describes summarizes research progress nanomedicine-based including chemotherapy, differentiation therapy, radioiodine gene targeted photothermal combination therapy. Furthermore, future challenges opportunities currently developed nanomedicines are discussed. As far as we know, there few reviews focusing on it believed that this will generate widespread interest from researchers variety fields to further expedite preclinical clinical translation nanomedicines.

Language: Английский

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Design of nanosystems for melanoma treatment

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 124701 - 124701

Published: Sept. 1, 2024

Language: Английский

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Recent advances in reactive oxygen species (ROS)-responsive drug delivery systems for photodynamic therapy of cancer

Acta Pharmaceutica Sinica B, Journal Year: 2024, Volume and Issue: 14(12), P. 5106 - 5131

Published: Nov. 2, 2024

Reactive oxygen species (ROS)-responsive drug delivery systems (DDSs) have garnered significant attention in cancer research because of their potential for precise spatiotemporal release tailored to high ROS levels within tumors. Despite the challenges posed by distribution heterogeneity and endogenous supply constraints, this review highlights strategic alliance ROS-responsive DDSs with photodynamic therapy (PDT), enabling selective leveraging PDT-induced enhanced therapeutic efficacy. This delves into biological importance progression treatment. We elucidate detail operational mechanisms linkers, including thioether, thioketal, selenide, diselencide, telluride aryl boronic acids/esters, as well latest developments nanomedicines that integrate PDT strategies. These insights are intended inspire design innovative nanocarriers PDT.

Language: Английский

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A comprehensive review on advances in nanoparticle-mediated cancer therapeutics: Current research and future perspectives

Cancer Pathogenesis and Therapy, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

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Modeling of Blood Flow in an Irregular Multi-stenosed Vessel in Presence of Iron Oxide and Gold Nanoparticles

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 8, 2025

Language: Английский

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Injectable Chitosan/Gelatin-based Microparticles Generated by Microfluidic Systems for Synergic Chemo-Photodynamic Therapy against Breast Cancer

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106904 - 106904

Published: April 1, 2025

Language: Английский

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Transformative potential of plant-based nanoparticles in cancer diagnosis and treatment: bridging traditional medicine and modern therapy

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Language: Английский

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