Computational identification of anti-cancer compounds targeting the RNA-binding domain of human FOX-1 protein (RBFOX1) DOI Creative Commons
Muhammad Tahir ul Qamar, Pablo Sanz-Jimenez, Shaima Rabeea Banoon

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 102004 - 102004

Published: Dec. 1, 2024

Language: Английский

A study on bio-synthesized gold nanoparticles via Hibiscus Platanifolius flower extract: Efficient strategy for cytotoxicity, photocatalytic potential, and green supercapacitor applications DOI

V. Lavanya,

K. Santhakumar

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 113886 - 113886

Published: Jan. 1, 2025

Language: Английский

Citations

2
Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s activities DOI Creative Commons
Manickam Rajkumar,

S. I. Davis Presley,

Nathiya Thiyagarajulu

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 15, 2025

Nanotechnology has experienced significant advancements, attracting considerable attention in various biomedical applications. This innovative study synthesizes and characterizes Ge/PLA/AuNCs (gelatin/PLA/gold nanocomposites) using Syzygium cumini extract to evaluate their The UV–Visible spectroscopy results an absorption peak at 534 nm were primarily confirmed by synthesis. FTIR spectrum showed functional groups the XRD patterns crystalline shape structure of nanocomposites. FESEM HRTEM a oval with average particle size 21 nm. Ge/PLA/AuNC's remarkable antioxidant activity, as evidenced DPPH (70.84 ± 1.64%), ABTS activity (86.17 1.96%), reducing power (78.42 1.48%) concentration 100 μg/mL was observed. zone inhibition against Staphylococcus aureus (19.45 0.89 mm) Echericia coli (20.83 0.97 revealed excellent antibacterial Ge/PLA/AuNCs. anti-diabetic supported α-amylase (82.56 1.49%) α-glucosidase (80.27 1.57%). anti-Alzheimer AChE (76.37 1.18%) BChE (85.94 1.38%) enzymes. In vivo studies zebrafish embryos that have biocompatibility nontoxicity. SH-SY5Y cell line demonstrated improved viability (95.27 1.62%) enhanced neuronal growth following treatment. conclusion, present highlights cost-effective non-toxic properties Furthermore, it presents attractive promising approach for future

Language: Английский

Citations

2
Sustainable Synthesis of Novel Green-Based Nanoparticles for Therapeutic Interventions and Environmental Remediation DOI
Swati Singh, Harshita Tiwari, Ashish Verma

et al.

ACS Synthetic Biology, Journal Year: 2024, Volume and Issue: 13(7), P. 1994 - 2007

Published: June 20, 2024

The advancement in nanotechnology has completely revolutionized various fields, including pharmaceutical sciences, and streamlined the potential therapeutic of many diseases that endanger human life. synthesis green nanoparticles by biological processes is an aspect newly emerging scientific field known as "green nanotechnology". Due to their safe, eco-friendly, nontoxic nature, tools are better suited produce between 1 100 nm. Nanoformulation different types been made possible using production techniques commercially feasible novel precursors, such seed extracts, algae, fungi, act potent reducing, capping, stabilizing agents. In addition this, biofunctionalization also broadened its horizon environmental remediation innovations wound healing, antimicrobial, anticancer, nano biosensing. However, major challenge pertaining agglomeration may alter surface topology, which can affect physiology, thereby contributing system toxicity. Therefore, a thorough grasp nanoparticle toxicity biocompatibility required harness applications therapeutics.

Language: Английский

Citations

13
Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects DOI Creative Commons
Hatice Duman, Emir Akdaşçi, Furkan Eker

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(22), P. 1805 - 1805

Published: Nov. 11, 2024

Gold nanoparticles (NPs) are among the most commonly employed metal NPs in biological applications, with distinctive physicochemical features. Their extraordinary optical properties, stemming from strong localized surface plasmon resonance (LSPR), contribute to development of novel approaches areas bioimaging, biosensing, and cancer research, especially for photothermal photodynamic therapy. The ease functionalization various ligands provides a approach precise delivery these molecules targeted areas. NPs' ability transfer heat electricity positions them as valuable materials advancing thermal management electronic systems. Moreover, their inherent characteristics, such inertness, give rise synthesis antibacterial antioxidant agents they provide biocompatible low-toxicity approach. Chemical physical methods utilized produce gold NPs. pursuit more ecologically sustainable economically viable large-scale technologies, environmentally benign processes referred green/biological synthesis, has garnered increasing interest global researchers. Green favorable than other techniques minimize necessity hazardous chemicals reduction process due simplicity, cost-effectiveness, energy efficiency, biocompatibility. This article discusses importance NPs, optical, conductivity, antibacterial, antioxidant, anticancer methods, contemporary uses, biosafety, emphasizing need understand toxicology principles green commercialization strategies.

Language: Английский

Citations

5
Emerging Trends in Smart and Sustainable Nano-Biosensing: The Role of Green Nanomaterials DOI Creative Commons
Shima Jafarzadeh, Nazila Oladzadabbasabadi, Mohammed Ali Dheyab

et al.

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 223, P. 120108 - 120108

Published: Nov. 26, 2024

Language: Английский

Citations

5
Iron Oxide Nanoparticles: Promising Agents for Biomedical Applications DOI
Asma Shahzad,

Sara Hanif

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 24, 2025

Language: Английский

Citations

0
Discovery of schinortriterpenoids schisaterpenes O–R from the fruits of Schisandra chinensis via molecular networking DOI
Peng Jiang,

Yumeng Luo,

Xinyuan Li

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141765 - 141765

Published: Feb. 1, 2025

Language: Английский

Citations

0
Myco-engineered Gold Nanoparticles and Their Employment as Biomedical Agents and Upscaling DOI
Asma Shahzad, Mehwish Iqtedar

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Language: Английский

Citations

0
Unveiling preferred chemoattractants for rhizosphere PGPR colonization by molecular docking and molecular dynamics simulations DOI Creative Commons
Ran Chai, Fuxin Li, Yuqian Gao

et al.

Computers and Electronics in Agriculture, Journal Year: 2024, Volume and Issue: 225, P. 109266 - 109266

Published: July 24, 2024

Unveiling the preferred chemoattractants of plant growth-promoting rhizobacteria (PGPR) toward rhizosphere is crucial for engineering PGPR to improve their chemotactic rhizocompetence. Here, we selected 59 common components root exudates and calculated binding free energies between ligand-binding domains (LBDs) 15 annotated chemoreceptors with extracellular LBDs in genome strain Pseudomonas sp. UW4 using molecular docking dynamics (MD) simulation. The absolute values lowest 18 out compounds logarithm capillary chemotaxis threshold concentrations showed a negative correlation. energy 1-aminocyclopropane-1-carboxylate (ACC) LBD corresponding chemoreceptor WP116 was among exudate analyzed. Knocking wp116 significantly reduced rate wheat microcosm system. These results that MD simulation are efficient analyzing affinities identifying chemoattractant rhizosphere, ACC determined be colonizing rhizosphere.

Language: Английский

Citations

2
Gold Nanoparticles as a Tool to Detect Biomarkers in Osteoarthritis: New Insights DOI
Atul Mourya,

Shristi Arya,

Ayush Singh

et al.

Indian Journal of Microbiology, Journal Year: 2024, Volume and Issue: unknown

Published: June 20, 2024

Language: Английский

Citations

0