Self-assembled PAMAM-G4 dendrimer nanoparticles with Phloxine B as photosensitizer for antimicrobial photodynamic therapy

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125534 - 125534

Published: March 1, 2025

Language: Английский

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One-step construction of silver nanoparticles immersed hydrogels by triple-helix β-glucans and the application in infectious wound healing

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137146 - 137146

Published: Oct. 1, 2024

Language: Английский

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Development of Films for Wound Healing Based on Gelatin and Oil/Water Emulsions as Carriers of Bioactive Compounds

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 357 - 357

Published: March 11, 2025

Background: Natural biopolymeric matrices for developing dressings have been extensively studied, as they may exhibit beneficial properties wound healing. Gelatin possesses promising structural and physicochemical incorporating active compounds (ACs). O/W emulsions are an alternative delivery system AC with different solubilities, promoting Objective: This study aimed to develop gelatin films by adding silver nanoparticles healing agents encapsulated in emulsion treat skin wounds. Methods: A film-forming dispersion was prepared using glycerol a plasticizer, were obtained the casting technique. Emulsions ACs (EAs) without (ECs) incorporated into films. The formulations analyzed FESEM characterized their mechanical, thermal, swelling properties, well water vapor permeability. Results: results showed that higher amount of exhibited greater rigidity lower permeability, while amounts demonstrated more elasticity General organ-specific toxicity evaluated zebrafish larvae. no lethal or sub-lethal effects on morphology activity brain, heart, liver. Conclusions: developed could provide stable support safe lesions, minimizing risk infection need heal wound.

Language: Английский

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Correlation Between Microscopic Current Fluctuations Observed at Ultra-Microelectrodes and Macroscopic Bulk Electrolysis Performance in Redox-Active Microemulsions

Journal of The Electrochemical Society, Journal Year: 2024, Volume and Issue: 171(11), P. 110502 - 110502

Published: Oct. 28, 2024

Microemulsions (μEs) have been proposed as redox flow battery (RFB) electrolytes that maximize ionic conductivity and charge capacity by synergizing two immiscible phases. However, transfer during electrolysis in μEs is poorly understood. Here, we show ultramicroelectrode of ferrocene-loaded −20%, 60%, 90% water - reveals stochastic current fluctuations. These are differentiated the scanning electrochemical microscopy (SECM) geometry, where power spectral density analysis showed distinct changes frequency contributions. SECM substrate generation-tip collection mode fluctuations arise under mass-transfer control. Significant differences diffusion coefficient ferrocene species were deducted from approach curves, suggesting phase behavior. Using bulk electrolysis, calculated accessibility cycling behavior μEs. A decrease seems to correlate a higher performance, with μE displaying best reversibility 60% lowest. Altogether, these results suggest Marangoni-type convection driven concentration gradients and/or restructuring play role performance This presents opportunities for screening diagnosing emerging RFB electrolytes.

Language: Английский

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Dermatological Nanotechnology: Gelatin films with O/W emulsions for skin lesion repair

European Journal of Pharmaceutics and Biopharmaceutics, Journal Year: 2024, Volume and Issue: 207, P. 114602 - 114602

Published: Dec. 6, 2024

Language: Английский

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