Coatings,
Journal Year:
2024,
Volume and Issue:
14(1), P. 70 - 70
Published: Jan. 4, 2024
Biofilms,
complex
microbial
communities,
adept
at
forming
on
diverse
surfaces
within
environments,
such
as
membrane
technologies,
ship
hulls,
medical
devices,
and
clinical
infections,
pose
persistent
challenges.
While
various
biofilm
prevention
methods,
including
antimicrobial
coatings,
physical
barriers,
bacteriophage
utilization,
have
been
devised
for
engineered
systems,
their
efficacy
fluctuates
based
application
type
species.
Consequently,
there
remains
a
pressing
need
the
development
of
highly
targeted
efficient
control
strategies
tailored
to
specific
applications
need.
In
our
investigation,
we
disrupt
cell-to-cell
communication
in
Pseudomonas
aeruginosa
through
anti-quorum
sensing
(anti-QS)
furanone
C-30
molecules.
The
incorporation
these
molecules
onto
electrospun
yielded
substantial
reductions
69%
petri
dish
assays
58%
mixed
cellulose
ester
(MCE)
membranes
dead-end
nanofiltration
system,
showcasing
potent
anti-biofouling
impact.
Notably,
functionalization
MCE
with
anti-QS
resulted
remarkable
16.7%
improvement
filtration
output.
These
findings
underscore
potential
this
approach
mitigate
formation,
offering
technical
foundation
advancing
ongoing
pursuit
effective
application-specific
measures.
The
occurrence
of
biofouling
restricts
the
widespread
application
membrane
bioreactors
(MBRs)
in
wastewater
treatment.
Regulation
quorum
sensing
(QS)
is
a
promising
approach
to
control
MBRs,
yet
underlying
mechanisms
are
complex
and
remain
be
illustrated.
A
fundamental
understanding
relationship
between
QS
MBRs
lacking,
which
hampers
development
quenching
(QQ)
techniques
(QQMBRs).
While
many
QQ
microorganisms
have
been
isolated
thus
far,
critical
criteria
for
selecting
desirable
still
missing.
Furthermore,
there
inconsistent
results
regarding
lifecycle
effects
on
physicochemical
characteristics
microbial
communities
mixed
liquor
assemblages
QQMBRs,
might
result
unreliable
inefficient
applications.
This
review
aims
comprehensively
summarize
timely
research
highlight
important
often
ignored
perspectives
MBRs.
We
consider
what
this
"information"
can
cannot
tell
us
explore
its
values
addressing
specific
questions
QQMBRs.
Herein,
we
first
examine
current
analytical
methods
signals
discuss
roles
fouling-forming
cornerstones
technologies.
To
achieve
targeting
strategies
propose
substrate
specificity
degradation
capability
surface
area
pore
structures
media
as
select
functional
microbes
media,
respectively.
validate
retardation
efficiency,
further
specify
properties,
community
composition,
succession
Finally,
provide
scale-up
considerations
QQMBRs
terms
debated
lifecycle,
practical
synergistic
strategies,
potential
cost
savings
presents
limitations
classic
QS/QQ
hypotheses
advances
role
development/retardation
builds
bridge
understandings
applications
technology.
