Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice DOI Creative Commons
Ping Tang,

Guangquan Ren,

Hongyang Zou

et al.

Current Research in Food Science, Journal Year: 2024, Volume and Issue: 8, P. 100734 - 100734

Published: Jan. 1, 2024

This study evaluated the effect of heat treatment on conversion ginsenoside and ameliorative heat-treated total (HG) from fresh ginseng cyclophosphamide (CTX)-induced liver injury. LC-MS analysis revealed that content rare ginsenosides increased markedly after treatment. HG significantly attenuated CTX-induced hepatic histopathological injury in mice. Western blotting showed untreated (UG) regulated Nrf2/HO-1 TLR4/MAPK pathways. Importantly, these results may be relevant to modulation intestinal flora. UG short-chain fatty acids (SCFAs)-producing bacteria Lactobacillus reduced LPS-producing Bacteroides Parabacteroides. These changes flora affected levels TNF-α, LPS SCFAs. In short, alleviated by regulating LPS-TLR4-MAPK pathway, was more effective. has potential a functional food can alleviate chemical

Language: Английский

Structural characterization and in vitro fermentation by rat intestinal microbiota of a polysaccharide from Porphyra haitanensis DOI
Peilin Chen,

Mingyao Tong,

Hongliang Zeng

et al.

Food Research International, Journal Year: 2021, Volume and Issue: 147, P. 110546 - 110546

Published: June 19, 2021

Language: Английский

Citations

35

Insights on preparation, structure and activities of Gracilaria lemaneiformis polysaccharide DOI Creative Commons
Xiaoshan Long, Xiao Hu, Shucheng Liu

et al.

Food Chemistry X, Journal Year: 2021, Volume and Issue: 12, P. 100153 - 100153

Published: Nov. 3, 2021

Gracilaria lemaneiformis is a kind of edible economic red algae, which rich in polysaccharide, phycobiliprotein, pigments, minerals and other nutrients functional components. Polysaccharide one the main active components lemaneiformis, has been reported to present various physiological bioactivities, including regulation glycolipid metabolism, immune, anti-tumor, anti-inflammatory biological activities. This paper aims provide brief summary extraction, purification, structural characteristics, activities polysaccharide (GLP). article able theoretical basis for future research exploitation GLP, improve its potential development promote healthy sustainable processing high value utilization industry

Language: Английский

Citations

35

Recent progress of Lycium barbarum polysaccharides on intestinal microbiota, microbial metabolites and health: a review DOI

Yuqin Feng,

Yating Song, Jie Zhou

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2022, Volume and Issue: 64(10), P. 2917 - 2940

Published: Sept. 28, 2022

Intestinal microbiota is symbiotically associated with host health, learning about the characteristics of and factors that modulate it could assist in developing strategies to promote human health prevent diseases. Polysaccharides from Lycium barbarum (LBPs) are found beneficial for enhancing activity gut microbiota, as a potential prebiotic, which not only participates improving body immunity, obesity, hyperlipidemia systemic inflammation induced by oxidative stress, but also plays magnificent role regulating intestinal microenvironment target effects via its biological activities, well metabolites. To highlight internal relationship between LBPs, this review focuses on latest advances LBPs metabolites, immune regulation, barrier protection, microbiota-gut-brain axis health. Moreover, preparation, structure, bioactivity modification were discussed. This may offer new perspective provide useful guidelines application food industry.

Language: Английский

Citations

27

Effects of Lycium barbarum Polysaccharides on Immunity and Metabolic Syndrome Associated with the Modulation of Gut Microbiota: A Review DOI Creative Commons

Cui Cao,

Zhongfu Wang, Guiping Gong

et al.

Foods, Journal Year: 2022, Volume and Issue: 11(20), P. 3177 - 3177

Published: Oct. 12, 2022

Lycium barbarum polysaccharides (LBPs) have attracted increasing attention due to their multiple pharmacological activities and physiological functions. Recently, both in vitro vivo studies demonstrated that the biological effects of dietary LBPs are related regulation gut microbiota. Supplementation with could modulate composition microbial communities, simultaneously influence levels active metabolites, thus exerting beneficial on host health. Interestingly, diverse chemical structures may enrich or reduce certain specific intestinal microbes. The present review summarizes extraction, purification, structural types microbiome derived metabolites. Furthermore, health promoting bidirectional immunity (e.g., immune enhancement inflammation suppression) metabolic syndrome obesity, type 2 diabetes, nonalcoholic fatty liver disease) by targeting microbiota also discussed based types. contents presented this might help better understand benefits provide a scientific basis further clarify structure–function relationship LBPs.

Language: Английский

Citations

26

Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice DOI Creative Commons
Ping Tang,

Guangquan Ren,

Hongyang Zou

et al.

Current Research in Food Science, Journal Year: 2024, Volume and Issue: 8, P. 100734 - 100734

Published: Jan. 1, 2024

This study evaluated the effect of heat treatment on conversion ginsenoside and ameliorative heat-treated total (HG) from fresh ginseng cyclophosphamide (CTX)-induced liver injury. LC-MS analysis revealed that content rare ginsenosides increased markedly after treatment. HG significantly attenuated CTX-induced hepatic histopathological injury in mice. Western blotting showed untreated (UG) regulated Nrf2/HO-1 TLR4/MAPK pathways. Importantly, these results may be relevant to modulation intestinal flora. UG short-chain fatty acids (SCFAs)-producing bacteria Lactobacillus reduced LPS-producing Bacteroides Parabacteroides. These changes flora affected levels TNF-α, LPS SCFAs. In short, alleviated by regulating LPS-TLR4-MAPK pathway, was more effective. has potential a functional food can alleviate chemical

Language: Английский

Citations

5