Critical Reviews in Food Science and Nutrition,
Journal Year:
2023,
Volume and Issue:
64(30), P. 10987 - 11005
Published: July 6, 2023
Diet
can
be
considered
as
one
of
the
pivotal
factors
in
regulating
gastrointestinal
health,
and
polyphenols
widely
distributed
human
daily
diet.
The
their
metabolites
playing
a
series
beneficial
effects
tract
that
regulate
gut
microbiota,
increase
intestinal
barrier
function,
repair
mucosa,
reduce
oxidative
stress,
inhibit
secretion
inflammatory
immune
absorption
biotransformation
mainly
depend
on
activity
microflora.
However,
little
is
known
about
two-way
interaction
between
microbiota.
objective
this
review
to
highlight
structure
optimization
effect
flavonoids
flora,
discusses
mechanisms
dietary
flora.
multiple
single
molecule
flavonoids,
inter-dependence
microbiota
polyphenol
metabolites.
Moreover,
protective
plant
macromolecules
health.
This
provided
valuable
insight
may
useful
for
better
understanding
mechanism
health
polyphenols,
provide
scientific
basis
application
functional
food.
Journal of Functional Foods,
Journal Year:
2023,
Volume and Issue:
108, P. 105765 - 105765
Published: Sept. 1, 2023
Insoluble
dietary
fiber
(IDF)
and
ZnSO4·7H2O
were
chelated
to
obtain
the
IDF-Zn.
The
Zn
ion
content
was
as
high
31.25
mg/g,
which
is
a
good
source
of
Zn-rich
products.
effects
IDF-Zn
on
metabolism
blood
lipid
levels
investigated
in
obese
rats.
Results
showed
that
compared
IDF
organic
(ZnSO4·7H2O),
can
significantly
reduce
body
weight,
total
cholesterol,
triglycerides,
low-density
lipoprotein
cholesterol
serum,
improve
liver
abnormal
sedimentation,
oxidation
stress
state,
enhance
immunity
Through
16S
rRNA
results,
intervention
decreased
ratio
Firmicutes/Bacteroidetes
increased
abundance
probiotics
(such
Lactobacillus,
Muribaculaceae,
Bacteroides),
cellulolytic
bacteria
Romboutsia
Clostridia-UCG-014).
These
results
suggest
adjust
intestinal
flora
structure
high-fat
diet
rats,
promote
health,
deposits,
ultimately
positively
impact
glucolipid
metabolism.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2023,
Volume and Issue:
64(25), P. 9113 - 9131
Published: May 4, 2023
In
the
human
body,
positive
effects
of
phenolic
compounds
are
increasingly
observed
through
their
presence
in
tissues
and
organs
native
form
or
metabolites
catabolites
formed
during
digestion,
microbial
metabolism,
host
biotransformation.
The
full
extent
these
is
still
unclear.
aim
this
paper
to
review
current
knowledge
beneficial
focusing
on
role
health
digestive
system,
including
disorders
gastrointestinal
urinary
tracts
liver.
Studies
mostly
connecting
tract
whole
food
rich
phenolics,
amount
compounds/antioxidants
food.
Indeed,
bioactivity
parent
should
not
be
ignored
due
tract,
impact
gut
microbiota.
However,
influence
might
more
important
for
liver
tract.
Distinguishing
between
phenolics
Journal of Food Science,
Journal Year:
2023,
Volume and Issue:
88(3), P. 1060 - 1074
Published: Jan. 25, 2023
Abstract
Walnut
green
husk
(WGH)
is
rich
in
natural
compounds
and
valued
as
a
potential
source
of
antioxidant
antimicrobial
properties.
In
this
study,
the
activities
petroleum
ether
polar
fraction,
dichloromethane
ethyl
acetate
fraction
(EAPF),
n
‐butanol
from
WGH
were
analyzed.
The
results
showed
that
EAPF
exhibited
highest
total
flavonoid
content
(65.74
±
1.01
mg
rutin
equivalents
[RE]/g
dry
weight
[DW])
phenol
(48.73
1.09
gallic
acid
equivalent
[GAE]/g
DW),
with
2,2‐diphenyl‐1‐picrylhydrazyl,
hydroxyl
radical
(•OH),
2,2‐azino‐bis‐3‐ethylbenzothiazoline‐6‐sulfonate
scavenging
activity
compared
other
fractions.
also
good
antibacterial
against
Escherichia
coli
Bacillus
cereus
vegetative
cells,
diameter
inhibition
zones
33.5
37.6
mm,
respectively,
minimum
inhibitory
concentration
31.25
mg/ml
bactericidal
62.5
mg/ml,
which
inhibited
growth
both
bacteria.
Analysis
mechanism
demonstrated
damaged
integrity
cell
membrane,
increased
membrane
permeability,
triggered
leakage
intracellular
material.
addition,
ultrahigh
performance
liquid
chromatography‐tandem
mass
spectrometry
analysis
revealed
8
polyphenols
14
flavonoids
mainly
present
EAPF,
such
chlorogenic
(C
16
H
18
O
9
),
7
6
5
vanillic
4
ferulic
10
epicatechin
15
catechin
hesperetin
naringenin
12
hyperin
21
20
luteolin
(C1
so
on.
Therefore,
had
to
be
developed
Practical
Application
Our
work
indicates
contains
abundant
compounds.
plant
byproducts
like
may
have
promising
application
additives.
Journal of Functional Foods,
Journal Year:
2023,
Volume and Issue:
110, P. 105877 - 105877
Published: Oct. 31, 2023
Acidic
walnut
green
husk
polysaccharide
with
weight
average
molecular
of
5.101
kDa
was
isolated
and
designated
WGHP-2,
which
composed
galacturonic
acid
(69.47
%),
galactose
(11.18
rhamnose
(8.67
arabinose
(3.96
glucose
(2.21
glucuronic
(2.28
xylose
(0.83
fucose
(0.81
%)
mannose
(0.59
%).
The
main
glycosidic
linkage
types
WGHP-2
were
→
4-α-D-Glcp-(1→,
→4-α-D-GalpA-(1→,
t-β-D-GlcpA-(1→,
→2-β-D-Rhap-(1→,
t-α-D-Galp-(1→,
→4-α-D-Galp-(1
2,4)-α-D-Manp(1
→.
Immunostimulating
assays
showed
that
could
significantly
promote
the
proliferation
RAW264.7
cells,
strengthen
phagocytic
activity,
up-regulate
production
release
NO,
ROS,
TNF-α,
INF-β
IL-6.
Western-blot
analysis
indicated
MAPK
PI3K/Akt
pathways
involved
in
activation
macrophages
induced
by
WGHP-2.
Overall,
our
study
suggests
has
potential
to
be
developed
as
a
functional
food
good
immunostimulatory
activity.
World Journal of Hepatology,
Journal Year:
2025,
Volume and Issue:
17(1)
Published: Jan. 6, 2025
Recent
research
indicates
that
the
intestinal
microbial
community,
known
as
gut
microbiota,
may
play
a
crucial
role
in
pathogenesis
of
nonalcoholic
fatty
liver
disease
(NAFLD).
To
understand
this
relationship,
study
used
comprehensive
bibliometric
analysis
to
explore
and
analyze
currently
little-known
connection
between
microbiota
NAFLD,
well
new
findings
possible
future
pathways
field.
provide
an
in-depth
current
focus
issues
developments
on
interaction
NAFLD.
In
study,
all
data
were
collected
from
Web
Science
Core
Collection,
related
searches
completed
one
day
(February
21,
2024).
The
stored
plain
text
format
facilitate
subsequent
analysis.
VOSviewer
1.6.20
CiteSpace
6.1R6
Basic
for
knowledge
graph
construction
included
total
1256
articles
published
2013
2023,
number
papers
demonstrated
upward
trend,
reaching
peak
last
two
years.
University
California,
San
Diego
held
highest
citation
count,
while
Shanghai
Traditional
Chinese
Medicine
China
led
works.
journal
"Nutrients"
had
publication
"Hepatology"
was
most
frequently
cited.
South
Korean
author
Suk
Ki
Tae
prolific
researcher.
co-cited
keyword
cluster
labels
revealed
ten
major
clusters,
namely
cortisol,
endothelial
dysfunction,
carbohydrate
metabolism,
myocardial
infarction,
non-alcoholic
steatohepatitis,
lipotoxicity,
glucagon-like
peptide-1,
non-islet
dependent,
ethnicity,
microRNA.
Keyword
outbreak
highlighted
metabolic
syndrome,
hepatic
steatosis,
insulin
resistance,
hepatocellular
carcinoma,
cardiovascular
disease,
permeability,
bacterial
overgrowth
prominent
areas
intense
research.
Through
quantitative
relevant
literature,
direction
NAFLD
can
be
more
clearly
understood,
which
helps
us
better
also
opens
up
innovative
solutions
strategies
treatment
Poultry Science,
Journal Year:
2024,
Volume and Issue:
103(11), P. 104176 - 104176
Published: Aug. 6, 2024
This
study
was
conducted
to
evaluate
the
effects
of
walnut
green
husk
extract
(WGHe)
on
growth
performance,
meat
quality,
antioxidative
status,
gut
morphology,
and
microbiota
diversity
broilers.
A
total
216
one-day-old
broilers
were
divided
into
4
groups,
each
consisting
9
replicates
(6
birds
per
replicate)
as
follows:
1)
control
group,
basal
diet;
2)
antibiotic
diet
supplemented
with
enduracidin
colistin
sulfate;
3)
low-dose
5.0
g/kg
WGHe;
4)
high-dose
10.0
WGHe.
The
results
revealed
that
percentage
abdominal
fat
decreased,
ratio
duodenal
villus
length
crypt
depth
(V/C),
well
α-diversity
ileal
microbiota,
increased
WGHe
supplementation
(P
<
0.05).
shear
force
breast
muscle
plasma
malondialdehyde
(MDA)
concentration
whereas
peroxidase
(POD)
activity,
Trolox
equivalent
antioxidant
capacity
(TEAC),
jejunal
in
response
Compared
diet,
addition
resulted
a
significant
increase
relative
abundances
Candidatus
Arthromitus,
Eubacterium
coprostanoligenes,
Ruminococcaceae
UCG-014
0.01).
Furthermore,
Arthromitus
Lachnoclostridium,
abundance
unidentified
Chloroplast
decreased
In
conclusion,
dietary
is
advantageous
for
intestinal
health,
status
broilers,
suggesting
its
potential
functional
additive
poultry
production.
