Processes,
Journal Year:
2023,
Volume and Issue:
11(11), P. 3192 - 3192
Published: Nov. 8, 2023
Research
into
extraction
kinetics
is
one
of
the
crucial
factors
in
a
technological
process.
Extraction
used
predominantly
when
working
with
organic
feedstock.
The
study
substance
complex
process,
which
influenced
by
large
number
factors.
This
paper
presents
an
analysis
these
factors,
namely
influence
reverse
sorption
on
process
release
from
matrix.
Sorption
can
directly
affect
intraparticle
diffusion
constants
and,
consequently,
rate
substance.
Using
buckwheat
husk
as
example,
its
capacity
was
assessed
to
assess
factor
melanin
release.
To
select
optimal
parameters
chemical
experiment
carried
out
at
temperatures
40,
50,
and
60
degrees
Celsius.
Axelrud
Baker–Lonsdale
equations
were
describe
kinetic
models.
Biomacromolecules,
Journal Year:
2024,
Volume and Issue:
25(9), P. 5489 - 5511
Published: Aug. 28, 2024
Emerging
material
interest
in
bioelectronic
applications
has
highlighted
natural
melanin
and
its
derivatives
as
promising
alternatives
to
conventional
synthetic
conductors.
These
materials,
traditionally
noted
for
their
adhesive,
antioxidant,
biocompatible,
biodegradable
properties,
have
barely
been
used
conductors
due
extremely
low
electrical
activities.
However,
recent
studies
demonstrated
good
conductive
properties
materials
that
promote
electronic-ionic
hybrid
charge
transfer,
attributed
the
formation
of
an
extended
conjugated
backbone.
This
review
examines
multifunctional
focusing
on
chemical
electrochemical
synthesis
resulting
structure-property-function
relationship.
The
wide
range
will
also
be
presented
highlight
importance
potential
expand
into
new
design
concepts
high-performance
electronic
functional
materials.
concludes
by
addressing
current
challenges
utilizing
bioelectronics,
providing
a
perspective
future
developments.
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(3), P. 480 - 480
Published: Feb. 21, 2025
Acetic
acid
bacteria
(AAB)
are
a
group
of
bacteria,
most
which
can
produce
pigments.
However,
the
mechanism
pigment
production
by
AAB
is
unclear.
A
strain
AAB,
Gluconacetobacter
tumulisoli
FBFS
97,
large
amount
brown
(BP),
was
isolated
in
our
previous
research.
In
current
study,
it
found
that
BP
yield
97
enhanced
presence
tyrosine,
and
an
intermediate
melanin,
L-3,4-dihydroxyphenylalanine
(L-DOPA),
identified
using
ultra-performance
liquid
chromatography–quadrupole
time-of-flight
mass
spectrometry
(UPLC-Q-TOF-MS).
The
structural
properties
were
analyzed
pyrolysis
gas
chromatography–mass
(Py-GC-MS).
All
these
analyses
suggest
may
be
eumelanin,
type
melanin.
Then,
eumelanin
biosynthetic
pathway
investigated
strain,
three
related
genes
with
including
pheA,
yfiH,
phhB
its
genome
knocked
out,
respectively.
results
showed
increased
1.3-fold
pheA
deletion
mutant
compared
to
wild-type
but
when
either
yfiH
or
mutants
same
as
strain.
Finally,
possible
for
proposed.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(7), P. 1535 - 1535
Published: March 30, 2025
The
2,4-dihydroxyphenyl
group
is
commonly
present
in
the
chemical
structures
of
potent
tyrosinase
inhibitors.
Based
on
this
observation,
a
series
6-(substituted
phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-d]thiazole
compounds
1–13
were
designed
and
synthesized
as
potential
Among
these,
5
9
strongly
inhibited
mushroom
activity.
Particularly,
compound
exhibited
nanomolar
IC50
values
regardless
substrate
used,
whereas
kojic
acid
yielded
15.99–26.18
μM.
Kinetic
studies
revealed
that
competitively
activity,
findings
further
corroborated
by
silico
docking
analysis.
In
B16F10
cell-based
experiments,
both
effectively
cellular
activity
melanin
formation.
These
inhibitory
effects
confirmed
through
situ
assays.
Compound
strong
antioxidant
scavenging
radicals,
suggesting
its
ability
to
reduce
production
may
be
attributed
combination
properties.
Additionally,
five
compounds,
including
5,
demonstrated
effective
depigmentation
vivo
zebrafish
embryos,
their
efficacy
was
similar
acid,
even
at
concentrations
hundreds
times
lower.
suggest
promising
anti-melanogenic
agents.
International Journal of Food Science,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
This
research
demonstrates
the
in
vivo
immunomodulatory
and
hepatoprotective
activities
of
soluble
melanins
Randia
echinocarpa
fruit
(PSM).
The
splenocyte
cellular
metabolic
activity
lymphocyte
T
γδ
expression
mesenteric
lymph
nodes
(MLNs)
Peyer
patches
(PPs)
were
measured
mice
model.
PSM
was
evaluated
CCl
4
‐induced
acute
hepatotoxic
injury
(AHTI)
rat
Compared
with
controls,
treatment
induced
higher
(in
vitro,
24.1%–57.25%;
vivo,
28.8%–47.7%),
activation
lymphocytes
MLN
but
suppression
PP.
Related
to
activity,
reduces
damage;
animals
showed
lower
levels
serum
ALT
(218.85–67.02
U/L)
ALP
(453.37–355.47
U/L),
GSH
(127.96–252.15
ng/mg
tissue),
hepatic
MDA
(10.25–7.85
nmol/mL),
less
severe
damage
histopathology.
These
results
suggest
nutraceutical
therapeutic
potential
PSM.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(16), P. 3382 - 3382
Published: Aug. 11, 2023
Sulfated
polysaccharides
isolated
from
seaweeds
are
thought
of
as
ideal
ingredients
in
the
pharmaceutical,
nutraceutical,
and
cosmetics
industries.
Our
previous
study
characterized
sulfated
Padina
boryana.
The
boryana
(PBP)
were
extracted,
antioxidant
activity
PBP
was
evaluated.
results
indicate
that
possesses
effects
potential
cosmetic
industry.
To
further
investigate
cosmetics,
photoprotective
anti-melanogenesis
test
display
reduced
melanin
content
murine
melanoma
cells
stimulated
by
alpha
melanocyte-stimulating
hormone
203.7%
to
183.64%,
144.63%,
127.57%
at
concentrations
25
μg/mL,
50
100
respectively.
anti-photodamage
showed
significantly
protected
skin
against
UVB-stimulated
photodamage.
suppressed
human
epidermal
keratinocyte
(HaCaT
cell)
death
inhibiting
apoptosis
reducing
level
intracellular
reactive
oxygen
species.
species
HaCaT
irradiated
UVB
192.67%
181.22%,
170.25%,
160.48%
μg/mL
PBP,
In
addition,
remarkably
UVB-induced
dermal
fibroblast
damage
suppressing
oxidative
damage,
collagen
degradation,
attenuating
inflammatory
responses.
These
activities
suggest
is
a
ingredient
Food Safety,
Journal Year:
2024,
Volume and Issue:
unknown, P. 475 - 496
Published: Jan. 16, 2024
Numerous
by-products
from
the
wastes
of
marine
items
can
be
obtained
and
utilized
in
a
wide
range
sectors.
The
cephalopod
are
evaluated
used
various
industries
(such
as
food,
medicine,
agriculture)
by
evaluating
head,
skin,
intestines,
ink,
etc.,
much
like
all
other
derived
goods.
Because
these
rich
nutrients
contain
biological
substances,
they
anticipated
to
improved
several
industries.
Additionally,
it
should
stated
that
research
produce
financial
gains
will
funded
things
acquired.
In
particular,
this
study
investigates
synthesis
antioxidant
antibacterial
agents,
extraction
bioactive
components
their
use
food
additives,
gelatin
peptides
by-products,
impact
on
extending
shelf
life,
health
risks
benefits
by-products.
Journal of Fungi,
Journal Year:
2023,
Volume and Issue:
9(8), P. 823 - 823
Published: Aug. 3, 2023
Pleurotus
ostreatus
is
widely
cultivated
in
China.
H2O2,
as
a
signaling
molecule,
can
regulate
the
formation
of
cap
color,
but
its
regulatory
pathway
still
unclear,
severely
inhibiting
breeding
dark-colored
strains.
In
this
study,
614
DEGs
specifically
regulated
by
H2O2
were
identified
RNA-seq
analysis.
GO-enrichment
analysis
shows
that
be
significantly
enriched
multiple
pathways
related
to
ATP
synthesis,
mainly
including
proton-transporting
synthesis
complex,
coupling
factor
F(o),
biosynthetic
process,
nucleoside
triphosphate
metabolic
processes,
purine
and
ribonuclease
processes.
Further
KEGG
revealed
23
involved
color
through
oxidative
phosphorylation
pathway.
They
Complexes
I,
III,
IV,
V
respiratory
chain.
addition
exogenous
uncoupling
agents
synthase
inhibitors
clarifies
important
role
formation.
summary,
may
upregulate
expression
complex-encoding
genes
chain
promote
thereby
affecting
color.
The
results
study
lay
foundation
for
strains
P.
provide
basis
color-formation
mechanism
edible
fungi.
