WITHDRAWN: Spirulina C-phycocyanin: extraction, purification, stabilization, and inhibitory potential of key enzymes rRelated to pancreas inflammation, carbohydrate digestion, and glucose metabolism DOI Creative Commons

Saber Abdelkader Saїdi,

Turki M. Al-Shaikh, Khaled Hamden

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 7, 2024

Abstract The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish work to be cited a reference. Questions should directed corresponding author.

Language: Английский

Nutraceutical Features of the Phycobiliprotein C-Phycocyanin: Evidence from Arthrospira platensis (Spirulina) DOI Open Access
Valentina Citi, Serenella Torre, Lorenzo Flori

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1752 - 1752

Published: June 3, 2024

Arthrospira platensis, commonly known as Spirulina, is a photosynthetic filamentous cyanobacterium (blue–green microalga) that has been utilized food source since ancient times. More recently, it gained significant popularity dietary supplement due to its rich content of micro- and macro-nutrients. Of particular interest water soluble phycobiliprotein derived from Spirulina phycocyanin C (C-PC), which stands out the most abundant protein in this cyanobacterium. C-PC fluorescent protein, with chromophore represented by tetrapyrrole molecule phycocyanobilin B (PCB-B). While employed for coloring properties, also serves molecular basis numerous nutraceutical features associated Spirulina. Indeed, comprehensive C-PC, some extent, isolated PCB-B, linked various health-promoting effects. These benefits encompass conditions triggered oxidative stress, inflammation, other pathological conditions. The present review focuses on bio-pharmacological properties these molecules, positioning them promising agents potential new applications expanding market.

Language: Английский

Citations

16

Mechanistic insights into the nutritional and therapeutic potential of Spirulina (Arthrospira) spp.: Challenges and opportunities DOI
Muhammad Abdur Rehman Shah, Feifei Zhu, Yi Cui

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 151, P. 104648 - 104648

Published: July 24, 2024

Language: Английский

Citations

11

Naturally Colored Ice Creams Enriched with C-Phycocyanin and Spirulina Residual Biomass: Development of a Fermented, Antioxidant, Tasty and Stable Food Product DOI Creative Commons
Monize Bürck, Camilly Fratelli, Marcelo Assis

et al.

Fermentation, Journal Year: 2024, Volume and Issue: 10(6), P. 304 - 304

Published: June 7, 2024

Naturally colored fermented foods currently represent the trend toward a global demand for healthier products. This work produced naturally blue and green ice creams using C-phycocyanin (C-PC) spirulina residual biomass (RB). The were assessed based on microbiological analysis, color stability over 6 months, antioxidant activity before after in vitro digestion, sensory evaluation. Considering microorganisms that must be analyzed accordance with Brazilian legislation, no growth was detected during storage period. L*, a*, b* maintained according to expected colors. intoned shelf life (SC-PC *b −9.46 −19.44 MC-PC from −9.87 −18.04). of SC-PC SRB increased 15.4 41.3 15.3 38.0 µM TE/g, respectively, bioaccessibility analysis. C-PC cream’s appearance received highest rating, 70.26% volunteers expressing strong preference, highlighting its attractiveness. However, there significant differences compared control samples acceptance. RB cream presented lower results flavor but moderate Thus, these their biological potential.

Language: Английский

Citations

8

A rapid one-step affinity purification of C-phycocyanin from Spirulina platensis DOI
Ke Shi, Wei Wang, Jingjing Sun

et al.

Journal of Chromatography A, Journal Year: 2024, Volume and Issue: 1720, P. 464801 - 464801

Published: March 6, 2024

Language: Английский

Citations

5

Unveiling the Potential of Spirulina Biomass—A Glimpse into the Future Circular Economy Using Green and Blue Ingredients DOI Creative Commons
Monize Bürck, Camilly Fratelli, Marina Campos Assumpção de Amarante

et al.

Biomass, Journal Year: 2024, Volume and Issue: 4(3), P. 704 - 719

Published: July 5, 2024

The present work aims to explore Spirulina biomass’ functional and technological marvels its components, such as C-phycocyanin (C-PC), in modern food systems from a circular economy perspective, evaluating decade of insights innovations. This comprehensive review delves into the pivotal studies past decade, spotlighting vital importance maintaining stability various matrices unleash full biological impacts. Through lens science intertwined with principles, this analysis meets health environmental requisites explores harmonious synergy between systems, economy, industry. While has typically served supplement, untapped potential fundamental ingredient been unveiled, showcasing abundant nutritional attributes. Technological hurdles preserving vibrant color C-PC have triumphantly surmounted through simple temperature control methods or cutting-edge nanotechnology applications. Despite gap sensory acceptance studies, emergence blue foods introduces groundbreaking innovative avenues for

Language: Английский

Citations

5

Phycocyanin attenuates skeletal muscle damage and fatigue via modulation of Nrf2 and IRS-1/AKT/mTOR pathway in exercise-induced oxidative stress in rats DOI Creative Commons

Sayomphu Puengpan,

Amnat Phetrungnapha,

Sarawut Sattayakawee

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(9), P. e0310138 - e0310138

Published: Sept. 10, 2024

Prolonged strenuous exercise induces oxidative stress, leading to damage, skeletal muscle fatigue, and reduced performance. The body compensates for stress through antioxidant actions, while related enzymes alone may not overcome excessive during prolonged exercise. Phycocyanin is an important supplement derived from blue-green algae, which be helpful in this type of situation. This study determined the effects phycocyanin on performance Forty Sprague Dawley male rats were divided into 5 groups (n = 8 /group); Control group (C), Exercise (E), with receiving low dose (Phycocyanin 100 mg/kg BW; ELP) high 200 EHP) or vitamin C (Vitamin VC). was found decrease damage markers, atrophy activated AKT/mTOR pathway. also have greater increases antioxidants via Nrf2 signaling ATP synthesis, GLUT4 transporters, insulin due increased IRS-1/AKT signaling. In conclusion, reduce atrophy, including increase muscles rats.

Language: Английский

Citations

4

Microalgal proteins: Extraction, interfacial properties, bioactivities, and future perspectives – A review DOI
Junwen Wang, Jiangfei Li,

Wenchen Yu

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 486, P. 144680 - 144680

Published: May 9, 2025

Language: Английский

Citations

0

Enhancing phycocyanin stability through encapsulation: optimization of maltodextrin and sodium alginate ratios DOI
Kerthika Devi Athiyappan,

Rayanee Chaudhuri,

P. Balasubramanian

et al.

Journal of Food Measurement & Characterization, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

Language: Английский

Citations

2

WITHDRAWN: Spirulina C-phycocyanin: extraction, purification, stabilization, and inhibitory potential of key enzymes rRelated to pancreas inflammation, carbohydrate digestion, and glucose metabolism DOI Creative Commons

Saber Abdelkader Saїdi,

Turki M. Al-Shaikh, Khaled Hamden

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 15, 2024

Abstract Background in recent years, it has become necessary to use natural food colorants protect against different diseases and disorders. The present study aimed purify, evaluate the stability, investigate effect of purified Spirulina C-Phycocyanin (CPC) on digestive metabolic enzymes linked hyperglycemia. Methods purification CPC was performed using column chromatography isolate compounds reversed-phase high performance liquid combined with diode array detector (DAD) ultraviolet spectroscopy (DAD-HPLC-UV) infrared Fourier transform (FTIR). Results findings this indicate that is stable at temperatures below 45°C a pH range 5 7, as well during storage 4°C. In diabetic rats, ingestion by rats suppressed key related inflammation pancreas, such 5-Lipoxygenase (5-LO), hyaluronidase (HAase), myeloperoxidase (MPO), NADPH oxidase (NOX2 activities) 48, 41, 75, 47%, respectively. Additionally, reduced pancreas thiobarbituric acid reactive substance rates (TBARS) 59%, stimulated level nitric oxide (NO) approximately 164%. Moreover, powerfully intestinal lipase, α-amylase, maltase, sucrose activities, significantly decreased glycosylated hemoglobin (HbA1c). Furthermore, glycogen phosphorylase (GP), Glycogen synthase (GS) regulated content liver rats. addition, supplementation modulated hepatic carbohydrate metabolism liver, hexokinase (HK), glucose-6-phosphate dehydrogenase (G6PD), glucose-6-phosphatase (G6P), fructose-1,6-bisphosphatase (FBP), average water intake (AFI AWI), resulting decrease blood glucose 56% compared untreated Conclusion Overall, results research showed can be used functional coloring compound prevent various pathologies ulcers, oxidative stress, diseases.

Language: Английский

Citations

0

WITHDRAWN: Spirulina C-phycocyanin: extraction, purification, stabilization, and inhibitory potential of key enzymes rRelated to pancreas inflammation, carbohydrate digestion, and glucose metabolism DOI Creative Commons

Saber Abdelkader Saїdi,

Turki M. Al-Shaikh, Khaled Hamden

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 7, 2024

Abstract The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish work to be cited a reference. Questions should directed corresponding author.

Language: Английский

Citations

0