Nutraceutical Features of the Phycobiliprotein C-Phycocyanin: Evidence from Arthrospira platensis (Spirulina)
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1752 - 1752
Published: June 3, 2024
Arthrospira
platensis,
commonly
known
as
Spirulina,
is
a
photosynthetic
filamentous
cyanobacterium
(blue–green
microalga)
that
has
been
utilized
food
source
since
ancient
times.
More
recently,
it
gained
significant
popularity
dietary
supplement
due
to
its
rich
content
of
micro-
and
macro-nutrients.
Of
particular
interest
water
soluble
phycobiliprotein
derived
from
Spirulina
phycocyanin
C
(C-PC),
which
stands
out
the
most
abundant
protein
in
this
cyanobacterium.
C-PC
fluorescent
protein,
with
chromophore
represented
by
tetrapyrrole
molecule
phycocyanobilin
B
(PCB-B).
While
employed
for
coloring
properties,
also
serves
molecular
basis
numerous
nutraceutical
features
associated
Spirulina.
Indeed,
comprehensive
C-PC,
some
extent,
isolated
PCB-B,
linked
various
health-promoting
effects.
These
benefits
encompass
conditions
triggered
oxidative
stress,
inflammation,
other
pathological
conditions.
The
present
review
focuses
on
bio-pharmacological
properties
these
molecules,
positioning
them
promising
agents
potential
new
applications
expanding
market.
Language: Английский
Mechanistic insights into the nutritional and therapeutic potential of Spirulina (Arthrospira) spp.: Challenges and opportunities
Trends in Food Science & Technology,
Journal Year:
2024,
Volume and Issue:
151, P. 104648 - 104648
Published: July 24, 2024
Language: Английский
Naturally Colored Ice Creams Enriched with C-Phycocyanin and Spirulina Residual Biomass: Development of a Fermented, Antioxidant, Tasty and Stable Food Product
Fermentation,
Journal Year:
2024,
Volume and Issue:
10(6), P. 304 - 304
Published: June 7, 2024
Naturally
colored
fermented
foods
currently
represent
the
trend
toward
a
global
demand
for
healthier
products.
This
work
produced
naturally
blue
and
green
ice
creams
using
C-phycocyanin
(C-PC)
spirulina
residual
biomass
(RB).
The
were
assessed
based
on
microbiological
analysis,
color
stability
over
6
months,
antioxidant
activity
before
after
in
vitro
digestion,
sensory
evaluation.
Considering
microorganisms
that
must
be
analyzed
accordance
with
Brazilian
legislation,
no
growth
was
detected
during
storage
period.
L*,
a*,
b*
maintained
according
to
expected
colors.
intoned
shelf
life
(SC-PC
*b
−9.46
−19.44
MC-PC
from
−9.87
−18.04).
of
SC-PC
SRB
increased
15.4
41.3
15.3
38.0
µM
TE/g,
respectively,
bioaccessibility
analysis.
C-PC
cream’s
appearance
received
highest
rating,
70.26%
volunteers
expressing
strong
preference,
highlighting
its
attractiveness.
However,
there
significant
differences
compared
control
samples
acceptance.
RB
cream
presented
lower
results
flavor
but
moderate
Thus,
these
their
biological
potential.
Language: Английский
A rapid one-step affinity purification of C-phycocyanin from Spirulina platensis
Journal of Chromatography A,
Journal Year:
2024,
Volume and Issue:
1720, P. 464801 - 464801
Published: March 6, 2024
Language: Английский
Unveiling the Potential of Spirulina Biomass—A Glimpse into the Future Circular Economy Using Green and Blue Ingredients
Biomass,
Journal Year:
2024,
Volume and Issue:
4(3), P. 704 - 719
Published: July 5, 2024
The
present
work
aims
to
explore
Spirulina
biomass’
functional
and
technological
marvels
its
components,
such
as
C-phycocyanin
(C-PC),
in
modern
food
systems
from
a
circular
economy
perspective,
evaluating
decade
of
insights
innovations.
This
comprehensive
review
delves
into
the
pivotal
studies
past
decade,
spotlighting
vital
importance
maintaining
stability
various
matrices
unleash
full
biological
impacts.
Through
lens
science
intertwined
with
principles,
this
analysis
meets
health
environmental
requisites
explores
harmonious
synergy
between
systems,
economy,
industry.
While
has
typically
served
supplement,
untapped
potential
fundamental
ingredient
been
unveiled,
showcasing
abundant
nutritional
attributes.
Technological
hurdles
preserving
vibrant
color
C-PC
have
triumphantly
surmounted
through
simple
temperature
control
methods
or
cutting-edge
nanotechnology
applications.
Despite
gap
sensory
acceptance
studies,
emergence
blue
foods
introduces
groundbreaking
innovative
avenues
for
Language: Английский
Phycocyanin attenuates skeletal muscle damage and fatigue via modulation of Nrf2 and IRS-1/AKT/mTOR pathway in exercise-induced oxidative stress in rats
Sayomphu Puengpan,
No information about this author
Amnat Phetrungnapha,
No information about this author
Sarawut Sattayakawee
No information about this author
et al.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(9), P. e0310138 - e0310138
Published: Sept. 10, 2024
Prolonged
strenuous
exercise
induces
oxidative
stress,
leading
to
damage,
skeletal
muscle
fatigue,
and
reduced
performance.
The
body
compensates
for
stress
through
antioxidant
actions,
while
related
enzymes
alone
may
not
overcome
excessive
during
prolonged
exercise.
Phycocyanin
is
an
important
supplement
derived
from
blue-green
algae,
which
be
helpful
in
this
type
of
situation.
This
study
determined
the
effects
phycocyanin
on
performance
Forty
Sprague
Dawley
male
rats
were
divided
into
5
groups
(n
=
8
/group);
Control
group
(C),
Exercise
(E),
with
receiving
low
dose
(Phycocyanin
100
mg/kg
BW;
ELP)
high
200
EHP)
or
vitamin
C
(Vitamin
VC).
was
found
decrease
damage
markers,
atrophy
activated
AKT/mTOR
pathway.
also
have
greater
increases
antioxidants
via
Nrf2
signaling
ATP
synthesis,
GLUT4
transporters,
insulin
due
increased
IRS-1/AKT
signaling.
In
conclusion,
reduce
atrophy,
including
increase
muscles
rats.
Language: Английский
Microalgal proteins: Extraction, interfacial properties, bioactivities, and future perspectives – A review
Junwen Wang,
No information about this author
Jiangfei Li,
No information about this author
Wenchen Yu
No information about this author
et al.
Food Chemistry,
Journal Year:
2025,
Volume and Issue:
486, P. 144680 - 144680
Published: May 9, 2025
Language: Английский
Enhancing phycocyanin stability through encapsulation: optimization of maltodextrin and sodium alginate ratios
Journal of Food Measurement & Characterization,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
Language: Английский
WITHDRAWN: Spirulina C-phycocyanin: extraction, purification, stabilization, and inhibitory potential of key enzymes rRelated to pancreas inflammation, carbohydrate digestion, and glucose metabolism
Saber Abdelkader Saїdi,
No information about this author
Turki M. Al-Shaikh,
No information about this author
Khaled Hamden
No information about this author
et al.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 15, 2024
Abstract
Background
in
recent
years,
it
has
become
necessary
to
use
natural
food
colorants
protect
against
different
diseases
and
disorders.
The
present
study
aimed
purify,
evaluate
the
stability,
investigate
effect
of
purified
Spirulina
C-Phycocyanin
(CPC)
on
digestive
metabolic
enzymes
linked
hyperglycemia.
Methods
purification
CPC
was
performed
using
column
chromatography
isolate
compounds
reversed-phase
high
performance
liquid
combined
with
diode
array
detector
(DAD)
ultraviolet
spectroscopy
(DAD-HPLC-UV)
infrared
Fourier
transform
(FTIR).
Results
findings
this
indicate
that
is
stable
at
temperatures
below
45°C
a
pH
range
5
7,
as
well
during
storage
4°C.
In
diabetic
rats,
ingestion
by
rats
suppressed
key
related
inflammation
pancreas,
such
5-Lipoxygenase
(5-LO),
hyaluronidase
(HAase),
myeloperoxidase
(MPO),
NADPH
oxidase
(NOX2
activities)
48,
41,
75,
47%,
respectively.
Additionally,
reduced
pancreas
thiobarbituric
acid
reactive
substance
rates
(TBARS)
59%,
stimulated
level
nitric
oxide
(NO)
approximately
164%.
Moreover,
powerfully
intestinal
lipase,
α-amylase,
maltase,
sucrose
activities,
significantly
decreased
glycosylated
hemoglobin
(HbA1c).
Furthermore,
glycogen
phosphorylase
(GP),
Glycogen
synthase
(GS)
regulated
content
liver
rats.
addition,
supplementation
modulated
hepatic
carbohydrate
metabolism
liver,
hexokinase
(HK),
glucose-6-phosphate
dehydrogenase
(G6PD),
glucose-6-phosphatase
(G6P),
fructose-1,6-bisphosphatase
(FBP),
average
water
intake
(AFI
AWI),
resulting
decrease
blood
glucose
56%
compared
untreated
Conclusion
Overall,
results
research
showed
can
be
used
functional
coloring
compound
prevent
various
pathologies
ulcers,
oxidative
stress,
diseases.
Language: Английский
WITHDRAWN: Spirulina C-phycocyanin: extraction, purification, stabilization, and inhibitory potential of key enzymes rRelated to pancreas inflammation, carbohydrate digestion, and glucose metabolism
Saber Abdelkader Saїdi,
No information about this author
Turki M. Al-Shaikh,
No information about this author
Khaled Hamden
No information about this author
et al.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Feb. 7, 2024
Abstract
The
full
text
of
this
preprint
has
been
withdrawn,
as
it
was
submitted
in
error.
Therefore,
the
authors
do
not
wish
work
to
be
cited
a
reference.
Questions
should
directed
corresponding
author.
Language: Английский