Effects of Fermented Kimchi Consumption on Anthropometric and Blood Cardiometabolic Indicators: A Systematic Review and Meta-Analysis of Intervention Studies and Prospective Cohort Studies DOI
Seoeun Ahn, Manije Darooghegi Mofrad, Briana M. Nosal

et al.

Nutrition Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 14, 2024

Abstract Context Increasing global kimchi consumption has prompted interest in its health impact. However, comprehensive reviews of the influence on cardiometabolic risk factors, especially meta-analyses, remain limited. Objective This review assessed impact fermented factors by systematically reviewing human intervention and prospective cohort studies, conducting a meta-analysis studies. Data Sources A literature search PubMed, EMBASE, Scopus, Web Science, RISS, KISS, ScienceON databases was conducted through April 30, 2024. The inclusion criteria encompassed studies that examined effects kimchi, without any added ingredients or lactic acid bacteria, outcomes, including anthropometric measures, blood pressure, glycemic indicators, inflammatory cytokines, incidence related chronic diseases. Extraction extraction quality evaluation were independently 3 researchers. Analysis Pooled effect sizes calculated as weighted mean differences (WMDs) with 95% CIs employing random-effects models. Results Five (205 participants) 4 (42 455 selected. revealed significant reduction fasting glucose (WMD: −1.93 mg/dL; CI: −3.82, −0.03; I2 = 17.4%) following kimchi. After excluding contributed to increased heterogeneity, inverse associations observed between triglycerides −28.9 −53.2, −4.5; 0.0%), systolic pressure −3.48 mmHg; −5.95, −1.01, diastolic −2.68 −4.75, −0.62; 0.0%). Prospective linked higher intake lower cancer metabolic syndrome an likelihood achieving normal body weight. Conclusion supports beneficial health. due limited number these findings should be interpreted cautiously, highlighting need for further research diverse populations. Systematic Review Registration PROSPERO registration No. CRD42024532020.

Language: Английский

Unveiling the Impact of Lactic Acid Bacteria on Blood Lipid Regulation for Cardiovascular Health DOI Creative Commons
Birsen Yılmaz, Neslihan Arslan, Teslime Özge Şahin

et al.

Fermentation, Journal Year: 2024, Volume and Issue: 10(7), P. 350 - 350

Published: July 9, 2024

Lactic acid bacteria (LAB) are a group of microorganisms which beneficial and well-characterized with respect to the flavor texture food products via fermentation. The accumulated literature has suggested that dietary intake fermented foods rich in LAB is related different health-promoting benefits; however, recent years, emerging evidence suggests contribution blood lipid regulation cardiovascular health certain mechanisms. Different potential mechanisms for regulatory effects may include interaction hydroxymethylglutaryl-CoA (HMG-CoA) reductase bile salt hydrolase activity metabolism; gut microbiome modulation; mRNA expression genes fat metabolism animal models human studies. This review comprehensively aims answer whether/how influence lipids both studies while also uncovering underlying linking metabolism.

Language: Английский

Citations

4
Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice DOI Creative Commons
Ye‐Rang Yun, Ji-Eun Lee

Nutrition Research, Journal Year: 2024, Volume and Issue: 124, P. 43 - 54

Published: Jan. 30, 2024

Kimchi is a traditional fermented food that contains abundant nutrients and functional ingredients with various health benefits. We previously reported kimchi active components suppress hepatic steatosis caused by endoplasmic reticulum (ER) stress in vitro vivo. Therefore, we assessed the effect of on inhibition ER HepG2 cells C57BL/6N mice to verify hypothesis may potentially inhibit non-alcoholic fatty liver disease. investigated cell viability triglyceride concentrations lipid profile, accumulation, expression related genes steatosis. A mechanistic study was also performed using X receptor α agonist T0901317 AMP-activated protein kinase AICAR. non-cytotoxic supplementation effectively reduced suppressed steatosis-related gene mice. Additionally, recovered weight loss, lowered serum tissue profiles, effects AICAR lipogenic tunicamycin-treated Our results highlight could prevent

Language: Английский

Citations

3
Effects of kimchi consumption on body fat and intestinal microbiota in overweight participants: A randomized, double-blind, placebo-controlled, single-center clinical trial DOI Creative Commons
Wooje Lee, Min‐Sung Kwon, Ye‐Rang Yun

et al.

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 121, P. 106401 - 106401

Published: Aug. 15, 2024

Language: Английский

Citations

2
Development a modified MRS medium for enhanced growth of psychrotrophic lactic acid bacteria isolated from kimchi DOI Creative Commons
Hye In Ko, Hae‐Il Yang, So-Rim Kim

et al.

LWT, Journal Year: 2024, Volume and Issue: unknown, P. 116815 - 116815

Published: Sept. 1, 2024

Language: Английский

Citations

2
Exploring the anti-obesity effects of kimchi through enhanced thermogenesis in differentiated T37i brown adipocytes DOI Creative Commons
Ye‐Rang Yun, Ji Eun Lee, Seongsoo Lee

et al.

Food & Nutrition Research, Journal Year: 2024, Volume and Issue: 68

Published: Aug. 29, 2024

Background: Previous research has demonstrated the anti-obesity effects of kimchi in 3T3-L1 adipocytes and mice with diet-induced obesity by assessing expression obesity-associated genes. Additionally, recent studies have identified mechanisms involving thermogenesis that support these effects. Objective: This study aims to further investigate properties kimchi, focusing on its impact thermogenic activity differentiated T37i brown adipocytes. Design: The first evaluated antioxidant potential using total capacity (TAC) ferric reducing power (FRAP) assays. Optimal differentiation conditions for were established before proceeding evaluations cell viability, intracellular triglyceride (TG) content, lipid accumulation, genes proteins related thermogenesis. Results: Kimchi maintained over 90% viability at concentrations up 1,000 μg/mL. Efficient preadipocytes was achieved a medium containing 10% calf serum, 2 nM 3,3',5-triiodo-L-thyronin (T3), 100 insulin. significantly reduced TG levels compared control group, enhanced while obesity-related Discussion: findings suggest exerts modulating pathways adipocytes, which may be partially attributed properties. Conclusions: shows promise as preventive measure against influencing metabolic associated both

Language: Английский

Citations

0
Studies on the Probiotic, Adhesion, and Induction Properties of Artisanal Lactic Acid Bacteria: to Customize a Gastrointestinal Niche to Trigger Anti-obesity Functions DOI
Aslıhan KAMBER, Çisem Bulut Albayrak,

H S Harsa

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Language: Английский

Citations

0
Effects of Fermented Kimchi Consumption on Anthropometric and Blood Cardiometabolic Indicators: A Systematic Review and Meta-Analysis of Intervention Studies and Prospective Cohort Studies DOI
Seoeun Ahn, Manije Darooghegi Mofrad, Briana M. Nosal

et al.

Nutrition Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 14, 2024

Abstract Context Increasing global kimchi consumption has prompted interest in its health impact. However, comprehensive reviews of the influence on cardiometabolic risk factors, especially meta-analyses, remain limited. Objective This review assessed impact fermented factors by systematically reviewing human intervention and prospective cohort studies, conducting a meta-analysis studies. Data Sources A literature search PubMed, EMBASE, Scopus, Web Science, RISS, KISS, ScienceON databases was conducted through April 30, 2024. The inclusion criteria encompassed studies that examined effects kimchi, without any added ingredients or lactic acid bacteria, outcomes, including anthropometric measures, blood pressure, glycemic indicators, inflammatory cytokines, incidence related chronic diseases. Extraction extraction quality evaluation were independently 3 researchers. Analysis Pooled effect sizes calculated as weighted mean differences (WMDs) with 95% CIs employing random-effects models. Results Five (205 participants) 4 (42 455 selected. revealed significant reduction fasting glucose (WMD: −1.93 mg/dL; CI: −3.82, −0.03; I2 = 17.4%) following kimchi. After excluding contributed to increased heterogeneity, inverse associations observed between triglycerides −28.9 −53.2, −4.5; 0.0%), systolic pressure −3.48 mmHg; −5.95, −1.01, diastolic −2.68 −4.75, −0.62; 0.0%). Prospective linked higher intake lower cancer metabolic syndrome an likelihood achieving normal body weight. Conclusion supports beneficial health. due limited number these findings should be interpreted cautiously, highlighting need for further research diverse populations. Systematic Review Registration PROSPERO registration No. CRD42024532020.

Language: Английский

Citations

0