Biosensors,
Journal Year:
2025,
Volume and Issue:
15(3), P. 183 - 183
Published: March 13, 2025
Food
safety
remains
a
significant
global
challenge
that
affects
human
health.
Various
hazards,
including
microbiological
and
chemical
threats,
can
compromise
food
throughout
the
supply
chain.
To
address
issues
ensure
public
health,
it
is
necessary
to
adopt
rapid,
accurate,
highly
specific
detection
methods.
Immunoassays
are
considered
be
an
effective
method
for
of
sensitive
biochemical
indicators
provide
efficient
platform
identification
hazards.
In
immunoassays,
antibodies
function
as
primary
recognition
elements.
Nanobodies
have
potential
valuable
biomolecules
in
diagnostic
applications.
Their
distinctive
physicochemical
structural
characteristics
make
them
excellent
candidates
development
reliable
assays,
promising
alternatives
monoclonal
polyclonal
antibodies.
Herein,
we
summarize
comprehensive
overview
status
prospects
nanobody-based
immunoassays
ensuring
safety.
First,
begin
with
historical
perspective
on
nanobodies
their
unique
characteristics.
Subsequently,
explore
definitions
boundaries
immunosensors,
before
discussing
applications
testing
emerged
over
past
five
years,
follow
different
highlighting
advantages
traditional
Finally,
directions
challenges
discussed.
Due
remarkable
sensitivity,
specificity
versatility,
hold
great
promise
revolutionizing
health
well-being.
Advances in Colloid and Interface Science,
Journal Year:
2023,
Volume and Issue:
322, P. 103035 - 103035
Published: Nov. 3, 2023
Surface-functionalized
nanostructures
are
at
the
forefront
of
biotechnology,
providing
new
opportunities
for
biosensors,
drug
delivery,
therapy,
and
bioimaging
applications.
The
modification
significantly
impacts
performance
success
various
applications
by
enabling
selective
precise
targeting.
This
review
elucidates
widely
practiced
surface
strategies,
including
click
chemistry,
cross-coupling,
silanization,
aldehyde
linkers,
active
ester
maleimide
epoxy
other
protein
DNA-based
methodologies.
We
also
delve
into
application-focused
landscape
nano-bio
interface,
emphasizing
four
key
domains:
therapeutics,
biosensing,
environmental
monitoring,
point-of-care
technologies,
highlighting
prominent
studies.
insights
presented
herein
pave
way
further
innovations
intersection
nanotechnology
a
useful
handbook
beginners
professionals.
draws
on
sources,
latest
research
articles
(2018-2023),
to
provide
comprehensive
overview
field.
Aggregate,
Journal Year:
2024,
Volume and Issue:
5(5)
Published: April 23, 2024
Abstract
It
is
crucial
to
realize
the
point‐of‐care
(POC)
testing
of
harmful
analytes,
capable
saving
limited
agricultural
resources,
assisting
environmental
remediation,
ensuring
food
safety,
and
enabling
early
disease
diagnosis.
Compared
with
other
conventional
POC
sensing
strategies,
aggregation‐based
analytical
chemistry
facilitates
practical‐oriented
development
nanosensors
by
altering
aggregation
status
nanoprobes
through
action
multiple
aggregation‐induced
“forces”
originating
from
targets.
Herein,
we
have
proceeded
a
comprehensive
review
focusing
on
in
nanosensors,
covering
“forces”,
signal
transductions,
nanosensing
their
applications
biomolecular
monitoring,
safety
analysis,
monitoring.
Finally,
challenges
existing
practical
been
further
proposed
improve
applications,
expect
our
can
speed
up
cost‐effective,
readily
deployable,
time‐efficient
chemistry.
