Long-term application of organic fertilizer prompting the dispersal of antibiotic resistance genes and their health risks in the soil plastisphere

Environment International, Journal Year: 2024, Volume and Issue: 183, P. 108431 - 108431

Published: Jan. 1, 2024

Microplastic (MP) pollution is a rapidly growing global environmental concern that has led to the emergence of new compartment, plastisphere, which hotspot for accumulation antibiotic resistance genes (ARGs) and human bacterial pathogens (HBPs). However, studies on effects long-term organic fertilizer application dispersal ARGs virulence factor (VFGs) in plastisphere farmland soil have been limited. Here, we performed field culture experiment by burying nylon bags filled with MPs paddy had treated different fertilizers over 30 years explore changes VFGs plastisphere. Our results show amplified ARG VFG caused fertilization 1.5 1.4 times, respectively. And it also 2.7-fold increase risk horizontal gene transfer. Meanwhile, tended promote deterministic process community assembly HBPs, an times. Network analysis found significant correlation between ARGs, VFGs, bacteria Correlation highlight important role mobile genetic elements (MGEs) communities shaping abundance findings provide insights into health associated due derived from fertilizers.

Language: Английский

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Antibiotics and microplastics in manure and surrounding soil of farms in the Loess Plateau: Occurrence and correlation

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 465, P. 133434 - 133434

Published: Jan. 4, 2024

Language: Английский

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Metagenomic analysis reveals gene taxonomic and functional diversity response to microplastics and cadmium in an agricultural soil

Environmental Research, Journal Year: 2024, Volume and Issue: 251, P. 118673 - 118673

Published: March 15, 2024

Language: Английский

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Climate warming, environmental degradation and pollution as drivers of antibiotic resistance

Environmental Pollution, Journal Year: 2024, Volume and Issue: 346, P. 123649 - 123649

Published: Feb. 23, 2024

Language: Английский

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Effects of microplastics on dissipation of oxytetracycline and its relevant resistance genes in soil without and with Serratia marcescens: Comparison between biodegradable and conventional microplastics

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 287, P. 117235 - 117235

Published: Nov. 1, 2024

The biodegradable (polybutylene adipate terephthalate: PBAT) and conventional (polyethylene: PE) microplastics (MPs) at 0.5 %, 1 2 % dosages (w/w) were added into soils with without Serratia marcescens ZY01 (ZY01, a tet-host strain) to understand their different effects on the dissipation of oxytetracycline (OTC) tet. results showed that PBAT MP exhibited inhibition degrees OTC biodegradation in regardless ZY01, while PE did not change enhancement degree ZY01. These differences due higher adsorption capacity stronger toxicity microorganisms. Besides soil organic matter, pH total phosphorus important factors regulating specific bacteria MPs (e.g., nitrogen-cycling Steroidobacter Nitrospira) + phosphorus-cycling Saccharimonadales Haliangium), respectively. Regardless selective harboring treatments than was observed dosage (w/w), opposite trend true (w/w). Some genera belonging Actinobacteriota strongly associated class integron-integrase gene (intI1), playing critical role horizontal transfer tet especially for co-existence This study will be helpful understanding how as hotspots affect environmental behavior antibiotics ARGs soil.

Language: Английский

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Microplastics enhance the prevalence of antibiotic resistance genes in mariculture sediments by enriching host bacteria and promoting horizontal gene transfer

Eco-Environment & Health, Journal Year: 2025, Volume and Issue: unknown, P. 100136 - 100136

Published: Jan. 1, 2025

Microplastics (MPs) and antibiotic resistance genes (ARGs) pose significant challenges to the One Health framework due their intricate multifaceted ecological environmental impacts. However, understanding of how MP properties influence ARG prevalence in mariculture sediments remains limited. Herein, polystyrene (PS) polyvinyl chloride (PVC) MPs with different sizes (20-120 μm 0.5-2.0 mm) were selected evaluate impacts underlying mechanisms driving ARGs dissemination. The results showed that PS PVC increased relative abundance by 1.41-2.50-fold 2.01-2.84-fold, respectively, compared control, particularly high-risk genes. polymer type effect was identified as more influential than size sediment resistome evolution. shifted microbial community assembly from stochastic deterministic processes, thus enriching host pathogens. Furthermore, highly hydrophobic not only recruited bacteria colonization but also facilitated exchange within plastisphere. exogenous additives released (e.g., heavy metals, bisphenol A, tridecyl ester) particles synergistically promoted conjugative transfer inducing oxidative stress enhancing cell membrane permeability. These findings revealed characteristics spread marine benthic ecosystems, underscoring importance mitigating pollution maintain ecosystem health, prevent zoonotic diseases, balance global health.

Language: Английский

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Insight into combined pollution of antibiotics and microplastics in aquatic and soil environment: Environmental behavior, interaction mechanism and associated impact of resistant genes

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 166, P. 117214 - 117214

Published: Aug. 2, 2023

Language: Английский

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Augmented dissemination of antibiotic resistance elicited by non-antibiotic factors

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 262, P. 115124 - 115124

Published: June 15, 2023

The emergence and rapid spread of antibiotic resistance seriously compromise the clinical efficacy current therapies, representing a serious public health threat worldwide. Generally, drug-susceptible bacteria can acquire through genetic mutation or gene transfer, among which horizontal transfer (HGT) plays dominant role. It is widely acknowledged that sub-inhibitory concentrations antibiotics are key drivers in promoting transmission resistance. However, accumulating evidence recent years has shown addition to antibiotics, non-antibiotics also accelerate genes (ARGs). Nevertheless, roles potential mechanisms non-antibiotic factors ARGs remain largely underestimated. In this review, we depict four pathways HGT their differences, including conjugation, transformation, transduction vesiduction. We summarize accounting for enhanced underlying molecular mechanisms. Finally, discuss limitations implications studies.

Language: Английский

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Fate and transport of biological microcontaminants bound to microplastics in the soil environment

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 892, P. 164439 - 164439

Published: May 27, 2023

Language: Английский

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Membrane-based technologies for removing emerging contaminants in urban water systems: Limitations, successes, and future improvements

Desalination, Journal Year: 2024, Volume and Issue: 590, P. 117974 - 117974

Published: Aug. 4, 2024

Language: Английский

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