Micro/Nanoplastic Exposure on Placental Health and Adverse Pregnancy Risks: Novel Assessment System Based upon Targeted Risk Assessment Environmental Chemicals Strategy

Toxics, Journal Year: 2024, Volume and Issue: 12(8), P. 553 - 553

Published: July 30, 2024

Micro/nanoplastics (MNPs), as emerging pollutants, have been detected in both the maternal and fetal sides of placenta pregnant women, their reproductive toxicity has demonstrated vivo vitro experimental models. The Targeted Risk Assessment Environmental Chemicals (TRAEC) strategy innovatively devised to facilitate valid risk assessment, encompassing a comprehensive evaluation reliability, correlation, outcome fitness, integrity across four dimensions based on included published evidence our own findings. This study serves an application case TRAEC, with 40 items research MNPs placenta, which were rigorously screened incorporated into final scoring system. score for this TRAEC is 5.63, suggesting moderate-to-low associated may potentially increase decreasing particle size. It essential emphasize that findings also report original data from assays indicating exposure high-dose groups (100 μg/mL, 200 μg/mL) 50 nm polystyrene nanoplastics (PS-NPs) induces HTR8/SVneo cell cycle arrest apoptosis, lead by disrupting mitochondrial function. Overall, employed provide insight potential health effects ubiquitous MNPs.

Language: Английский

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Impacts of Environmental Concentrations of Nanoplastics on Zebrafish Neurobehavior and Reproductive Toxicity

Toxics, Journal Year: 2024, Volume and Issue: 12(8), P. 617 - 617

Published: Aug. 21, 2024

Nanoplastics, as emerging environmental pollutants, can transport contaminants across marine environments, polluting pristine ecosystems and being ingested by organisms. This transfer poses a severe threat to global aquatic potentially impacts human health through the food chain. Neurobehavioral reproductive toxicity are critical areas of concern because they directly affect survival, health, population dynamics species, which have cascading effects on entire ecosystem. Using zebrafish model organism, we investigated toxic concentrations polystyrene nanoplastics (PS-NPs). Behavioral assessments, including novel tank test open field test, demonstrated significant neurobehavioral changes, indicating increased anxiety depressive behaviors. A pathological analysis brain gonadal tissues, along with evaluations biomarkers, revealed that exposure PS-NPs leads tissue lesions, inflammatory responses, oxidative stress activation, hormone level disruptions, damage. Real-time quantitative PCR studies gene expression further showed disrupt endocrine regulation pathways brain-pituitary-gonadal (BPG) axis, causing sex-specific differences. These findings provide crucial insights into organisms their ecological risks, offering theoretical support for future protection pollutant management efforts.

Language: Английский

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A review on sustainable management strategies for navigating the piling e-waste crisis and associated environmental threats

Toxicology, Journal Year: 2024, Volume and Issue: 511, P. 154019 - 154019

Published: Nov. 30, 2024

Language: Английский

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Biodegradable sponges made from chitin-cellulose nanofibers for sustainable removal of microplastics from aquatic environment

Journal of Hazardous Materials Advances, Journal Year: 2024, Volume and Issue: unknown, P. 100564 - 100564

Published: Dec. 1, 2024

Language: Английский

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Identification and Quantification of Microplastics Released During Actual Use of Disposable Cups

Published: Jan. 1, 2024

Disposable plastic cups are commonly utilized as beverage containers due to their hygienic and convenient benefits. This work aims investigate the characteristics of microplastic discharge from single-use in everyday situations assess emission microplastics six sets disposable cups, comprising polypropylene (PP) polystyrene (PS) cups. We systematically examined impact material, water temperature, liquid type on release microplastics, utilizing LDIR for identification, qualitative, quantification analysis microplastics. The findings indicated that all detected irregularly shaped primarily smaller than 50μm. When filled with pure at 95°C 15 minutes, average concentration PP PS was 1340 980 particles L-1, respectively. exhibited a higher under elevated temperature conditions; conversely, low temperatures facilitated self-release Furthermore, use reusable resulted decreased levels compared study estimated regular cup three times day could potentially lead an inadvertent ingestion 294-402 per day. These results provide basis future evaluation possible health hazards linked human contact

Language: Английский

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High-sensitivity SERS Sensor Leveraging Three-dimensional Ti3C2Tx/TiO2/W18O49 Semiconductor Heterostructures for Reliable Detection of Trace Micro/Nanoplastics in Environmental Matrices

Talanta, Journal Year: 2024, Volume and Issue: 286, P. 127474 - 127474

Published: Dec. 26, 2024

Language: Английский

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