Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 493, P. 138372 - 138372
Published: April 21, 2025
Language: Английский
Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 493, P. 138372 - 138372
Published: April 21, 2025
Language: Английский
Environmental Pollution, Journal Year: 2025, Volume and Issue: 368, P. 125771 - 125771
Published: Jan. 31, 2025
Language: Английский
Citations
0International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1360 - 1360
Published: Feb. 6, 2025
Non-alcoholic fatty liver disease (NAFLD), the most prevalent chronic illness, is characterized by hepatic steatosis. Exercise and probiotics can regulate gut microbiota to treat NAFLD; however, their combined effects mechanisms of gut-liver communication remain unclear. Inconsistent results on probiotic efficacy further warrant investigation. In this study, zebrafish fed a high-fat diet (HFD) for six weeks were subjected swimming exercise (HFDE), intervention (HFDP), or combination both (HFDEP) 10 explore NAFLD corresponding mechanism. The showed that alleviation followed order HFDEP > HFDE HFDP. treatments effectively reduced Body Mass Index (BMI), relative weight, vacuolation density, lipid droplets in sections, triglyceride, free acid, glucose, pyruvic acid. contrast, single treatment had limited impact, suggesting complementary role treatment. Glucose acid metabolism central “gut–liver” axis. conversion glucose decreased synthesis esterification, accelerated transformation CO2 contributed improvement under treatments. This study provides promising theoretical groundwork potential prevention strategies NAFLD.
Language: Английский
Citations
0Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 493, P. 138372 - 138372
Published: April 21, 2025
Language: Английский
Citations
0