COVID-19 and long-term neurological problems: Challenges ahead with Post-COVID-19 Neurological Syndrome DOI Creative Commons
Tissa Wijeratne, Sheila G. Crewther

Australian Journal of General Practice, Journal Year: 2021, Volume and Issue: 50

Published: Jan. 12, 2021

The pandemic statistics highlight the need for ongoing, careful follow-up of all patients with COVID-19 regular screening likely long-term persistent neurological involvements.

Language: Английский

Long COVID, a comprehensive systematic scoping review DOI Open Access
Hossein Akbarialiabad, Mohammad Hossein Taghrir, Ashkan Abdollahi

et al.

Infection, Journal Year: 2021, Volume and Issue: 49(6), P. 1163 - 1186

Published: July 28, 2021

Language: Английский

Citations

292

Post-COVID-19 symptoms 6 months after acute infection among hospitalized and non-hospitalized patients DOI Creative Commons
Maddalena Peghin, Alvisa Palese,

Margherita Venturini

et al.

Clinical Microbiology and Infection, Journal Year: 2021, Volume and Issue: 27(10), P. 1507 - 1513

Published: June 7, 2021

Language: Английский

Citations

282

Post-COVID syndrome and suicide risk DOI Open Access
Leo Sher

QJM, Journal Year: 2021, Volume and Issue: 114(2), P. 95 - 98

Published: Jan. 8, 2021

A significant number of coronavirus disease SARS-CoV-2 (COVID-19) patients continue to have symptoms related COVID-19 after the acute phase illness. This post-COVID condition is sometimes called 'post-COVID syndrome', 'long COVID' or 'post-acute COVID-19'. Persistent psychiatric among survivors such as depression, anxiety, post-traumatic and cognitive impairment may be psychological factors neurobiological injury. neurological including anosmia, ageusia, dizziness, headache seizures persist for a long time Many experience persistent physical cough, fatigue, dyspnea pain recovering from their initial There high probability that psychiatric, illnesses, well inflammatory damage brain in individuals with syndrome increase suicidal ideation behavior this patient population. without also at elevated suicide risk. Studies suicidality are urgently needed will new area research. An appropriate management medical conditions reduce risk syndrome.

Language: Английский

Citations

140

Post-COVID 19 neurological syndrome: Implications for sequelae’s treatment DOI Creative Commons
William Camargo-Martínez, Iván David Lozada-Martínez,

Angie Escobar-Collazos

et al.

Journal of Clinical Neuroscience, Journal Year: 2021, Volume and Issue: 88, P. 219 - 225

Published: April 8, 2021

Study designLiterature review.ObjectivesDescribe the implications of post-COVID syndrome due to neurological sequelae including treatment and differences that may exist between this group patients those who present these events not associated with COVID-19.MethodsA non-systematic review literature was carried out in PubMed Science Direct databases, using keywords "Post-acute COVID-19 syndrome"; "Neurological complications"; "Neurologic Manifestations" "COVID-19″ "Rehabilitation", as well synonyms, which were combined operators "AND" "OR".ResultsThe viral caustive agent, SARS-CoV-2, has a high affinity for human angiotensin-converting enzyme 2 receptor on type II pneumocytes. This is also expressed neurons glial cells. Based foregoing other so clear mechanisms, it stated SARS-CoV-2 tropism nervous system, being evident through manifestations observed mild, moderate severe phenotype disease such anosmia, ageusia, headache, cerebrovascular accidents, Guillain-Barré syndrome, seizures, encephalopathy. can generate even fatal outcomes affected.ConclusionsNeurological complications caused by are frequent represent risk compromises functional capacity life patients. The suspicion conditions, strict control metabolic alterations cardiovascular factors, effective safe entities, current challenge throughout pandemic. rehabilitation process challenge. limitations generated multi-organ damage, brain death.

Language: Английский

Citations

118

Evolving phenotypes of non-hospitalized patients that indicate long COVID DOI Creative Commons
Hossein Estiri, Zachary H. Strasser, Gabriel A. Brat

et al.

BMC Medicine, Journal Year: 2021, Volume and Issue: 19(1)

Published: Sept. 26, 2021

For some SARS-CoV-2 survivors, recovery from the acute phase of infection has been grueling with lingering effects. Many symptoms characterized as post-acute sequelae COVID-19 (PASC) could have multiple causes or are similarly seen in non-COVID patients. Accurate identification PASC phenotypes will be important to guide future research and help healthcare system focus its efforts resources on adequately controlled age- gender-specific a infection.In this retrospective electronic health record (EHR) cohort study, we applied computational framework for knowledge discovery clinical data, MLHO, identify that positively associate past positive reverse transcription-polymerase chain reaction (RT-PCR) test COVID-19. We evaluated post-test two temporal windows at 3-6 6-9 months after by age gender. Data longitudinal diagnosis records stored EHRs Mass General Brigham Boston Metropolitan Area was used analyses. Statistical analyses were performed data March 2020 June 2021. Study participants included over 96 thousand patients who had tested negative not hospitalized.We identified 33 among different age/gender cohorts time associated infection. All newly recorded patients' medical 2 longer RT-PCR non-hospitalized regardless result. Among these phenotypes, new anosmia dysgeusia (OR 2.60, 95% CI [1.94-3.46]), alopecia 3.09, [2.53-3.76]), chest pain 1.27, [1.09-1.48]), chronic fatigue syndrome [1.22-2.10]), shortness breath 1.41, [1.22-1.64]), pneumonia 1.66, [1.28-2.16]), type diabetes mellitus [1.22-1.64]) is one most significant indicators Additionally, more found increased confidence younger than 65.The findings study confirm many post-COVID-19 suggest variety diagnoses, including neurological disorder common those history without 63% observed under 65 years age, pointing out importance vaccination minimize risk debilitating adults.

Language: Английский

Citations

114

The Impact of COVID-19 Traumatic Stressors on Mental Health: Is COVID-19 a New Trauma Type DOI Creative Commons
Ibrahim A. Kira, Hanaa Shuwiekh, Jeffrey S. Ashby

et al.

International Journal of Mental Health and Addiction, Journal Year: 2021, Volume and Issue: 21(1), P. 51 - 70

Published: July 6, 2021

COVID-19 is a new type of trauma that has never been conceptually or empirically analyzed in our discipline. This study aimed to investigate the impact as traumatic stress on mental health after controlling for individuals' previous stressors and traumas. We utilized sample (N = 1374) adults from seven Arab countries. used an anonymous online questionnaire included measures stress, posttraumatic disorder, anxiety, depression, cumulative conducted hierarchical multiple regression, with anxiety dependent variables. In first step, each analysis, we entered country, gender, age, religion, education, income independent variables (Kira, Traumatology 7(2):73–86, 2001; Kira, Torture, 14:38–44, 2004; Traumatology, 2021, https://doi.org/10.1037/trm0000305). second traumas variable. third either one its subtypes (fears infection, economic, lockdown) Finally, structural equation modeling PTSD, predictors latent variable Results indicated stressors, three subtypes, were unique depression. Thus, serious effects.

Language: Английский

Citations

111

Psychiatric and neurological complications of long COVID DOI Creative Commons
Jolanta B. Zawilska, K Kuçzyńska

Journal of Psychiatric Research, Journal Year: 2022, Volume and Issue: 156, P. 349 - 360

Published: Oct. 20, 2022

Language: Английский

Citations

109

Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems DOI Open Access
Valeria Visco, Carolina Vitale,

Antonella Rispoli

et al.

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(3), P. 524 - 524

Published: Jan. 20, 2022

Though the acute effects of SARS-CoV-2 infection have been extensively reported, long-term are less well described. Specifically, while clinicians endure to battle COVID-19, we also need develop broad strategies manage post-COVID-19 symptoms and encourage those affected seek suitable care. This review addresses possible involvement lung, heart brain in post-viral syndromes describes suggested management syndrome. Post-COVID-19 respiratory manifestations comprise coughing shortness breath. Furthermore, arrhythmias, palpitations, hypotension, increased rate, venous thromboembolic diseases, myocarditis failure usual cardiovascular events. Among neurological manifestations, headache, peripheral neuropathy symptoms, memory issues, lack concentration sleep disorders most commonly observed with varying frequencies. Finally, mental health issues affecting abilities mood fluctuations, namely anxiety depression, frequently seen. long COVID is a complex syndrome protracted heterogeneous patients who experience sequelae require personalized treatment as ongoing support.

Language: Английский

Citations

101

The Protective Effect of Coronavirus Disease 2019 (COVID-19) Vaccination on Postacute Sequelae of COVID-19: A Multicenter Study From a Large National Health Research Network DOI Creative Commons
Sokratis N. Zisis, Jared Durieux, Christian Mouchati

et al.

Open Forum Infectious Diseases, Journal Year: 2022, Volume and Issue: 9(7)

Published: May 7, 2022

Coronavirus disease 2019 (COVID-19) vaccines have been proven to decrease the severity of acute-phase infection; however, little is known about their effect on postacute sequelae COVID-19 (PASC).

Language: Английский

Citations

74

The emotional well-being of Long COVID patients in relation to their symptoms, social support and stigmatization in social and health services: a qualitative study DOI Creative Commons
Mario Samper-Pardo, Bárbara Oliván‐Blazquez, Rosa Magallón-Botaya

et al.

BMC Psychiatry, Journal Year: 2023, Volume and Issue: 23(1)

Published: Jan. 25, 2023

Long COVID patients have experienced a decline in their quality of life due to, part but not wholly, its negative emotional impact. Some the most prevalent mental health symptoms presented by long are anxiety, depression, and sleep disorders. As such, need has arisen to analyze personal experiences these understand how they managing daily lives while dealing with condition. The objective this study is increase understanding about well-being people diagnosed COVID.

Language: Английский

Citations

60