Association of vitamins and minerals with COVID-19: A mini review DOI Open Access

Khaldoon Jasim Mohammed,

Ahmed Falah Imran,

Salam Kitab Rubat

et al.

Asia-Pacific Journal of Molecular Biology and Biotechnology, Journal Year: 2024, Volume and Issue: unknown, P. 11 - 20

Published: July 4, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of disease 2019 (COVID-19). SARS-CoV-2 has potential to multiorgan failure (MOF), which lethal. This review aims evaluate levels some vitamins (vitamins C, A, D, and E) minerals (zinc, iron, selenium) in individuals infected with coronavirus. All studies reviewed indicate a deficiency mentioned above. We conclude that micronutrients play significant role immune system their deficiencies have effect on system. Although most antioxidants are believed be present diets, it been suggested taking more will boost immunity. constantly active, specific immunity activated when pathogens present. The metabolites vitamin other nutrients control expression genes cells.

Language: Английский

Natural Ingredients to Improve Immunity DOI Creative Commons
Amin Gasmi, Mariia Shanaida, Oleksandra Oleshchuk

et al.

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(4), P. 528 - 528

Published: April 1, 2023

The immune system protects the body from infectious agents such as bacteria, viruses, or fungi. Once encountered with pathogens antigens, innate and adaptive arms of trigger a strong response to eliminate them protect body. Thus, well-balanced immunity is pivotal for maintaining human health, an insufficient level defense leads infections tumors. In contrast, excessive functioning causes development autoimmune diseases allergies. Strong requires adequate nutrition, dietary interventions, sufficient intake certain vitamins (vitamin C, vitamin D, folic acid) minerals (magnesium, zinc, selenium). Therefore, nutritional micronutrient deficiencies lead compromised immunity. Several natural ingredients have shown potent immunomodulatory properties. immune-enhancing properties many plants fungi are due containing bioactive phytoconstituents polyphenols, terpenoids, β-glucans, vitamins, etc. Probiotics prebiotics can be used innovative tools reduce intestinal inflammation downregulate hypersensitivity reactions. Plant sources melatonin, multifunctional molecule proven anti-inflammatory properties, been discovered relatively recently. compounds augment by directly increasing cytotoxic activity killer cells, macrophages, neutrophils. Many prevent cell damage their powerful antimicrobial, antioxidant, present review attempts understand molecular mechanisms underlying some plants, fungi, animals, microorganisms, other sources.

Language: Английский

Citations

47
Advances in siRNA delivery approaches in cancer therapy: challenges and opportunities DOI

Houman Isazadeh,

Farshid Oruji, Shima Shabani

et al.

Molecular Biology Reports, Journal Year: 2023, Volume and Issue: 50(11), P. 9529 - 9543

Published: Sept. 23, 2023

Language: Английский

Citations

33
Are Nutraceuticals Effective in COVID-19 and Post-COVID Prevention and Treatment? DOI Creative Commons
Alessia Catalano, Domenico Iacopetta, Jessica Ceramella

et al.

Foods, Journal Year: 2022, Volume and Issue: 11(18), P. 2884 - 2884

Published: Sept. 17, 2022

The beginning of the end or beginning? After two years mastered by coronavirus disease 19 (COVID-19) pandemic, we are now witnessing a turnaround. reduction severe cases and deaths from COVID-19 led to increasing importance new called post-COVID syndrome. term is used indicate permanency symptoms in patients who have recovered acute respiratory syndrome 2 (SARS-CoV-2) infection. Immune, antiviral, antimicrobial therapies, as well ozone therapy been treat disease. Vaccines then become available administered worldwide prevent insurgence However, pandemic not over yet at all given emergence omicron variants. New therapeutic strategies urgently needed. In this view, great interest was found nutraceutical products, including vitamins (C, D, E), minerals (zinc), melatonin, probiotics, flavonoids (quercetin), curcumin. This review summarizes role nutraceuticals prevention and/or treatment

Language: Английский

Citations

37
Pattern-recognition receptors (PRRs) in SARS-CoV-2 DOI
Alireza Isazadeh, Javad Ahmadian Heris, Parviz Shahabi

et al.

Life Sciences, Journal Year: 2023, Volume and Issue: 329, P. 121940 - 121940

Published: July 12, 2023

Language: Английский

Citations

17
COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches DOI Creative Commons

Sareh Kakavandi,

Bahareh Hajikhani, Paniz Azizi

et al.

Cell Communication and Signaling, Journal Year: 2024, Volume and Issue: 22(1)

Published: Feb. 15, 2024

Abstract Extensive research in countries with high sociodemographic indices (SDIs) to date has shown that coronavirus disease 2019 (COVID-19) may be directly associated more severe outcomes among patients living haematological disorders and malignancies (HDMs). Because individuals moderate immunodeficiency are likely undergo persistent infections, shed virus particles for prolonged periods, lack an inflammatory or abortive phase, this represents overall risk of morbidity mortality from COVID-19. In cases suffering HDMs, further investigation is needed achieve a better understanding triviruses group related variants anemia as well their treatment through vaccines, drugs, other methods. Against background, the present study aimed delineate relationship between HDMs novel COVID-19, acute respiratory syndrome 2 (SARS-CoV-2). Besides, effective options HDM were explored address epidemic its variants. Therefore, learning about how COVID-19 manifests these patients, along exploiting most appropriate treatments, lead development care strategies by clinicians researchers help recover faster.

Language: Английский

Citations

7
Micronutrients throughout the Life Cycle: Needs and Functions in Health and Disease DOI
Mohit Kumar,

Devesh Kumar,

Ankita Sharma

et al.

Current Nutrition & Food Science, Journal Year: 2023, Volume and Issue: 20(1), P. 62 - 84

Published: April 20, 2023

Background: Micronutrients play a vital role in the maintenance and proper functioning of body tissues. broadly consist minerals vitamins. These vitamins are supreme importance treatment an eclectic variety diseases obligatory for many metabolic processes. Objective: The objective this review is to give comprehensive overview on micronutrients broad-spectrum also insightful knowledge regarding numerous food sources obtaining nutrients, their dietary reference values, deficiencies. In review, authors have highlighted COVID- 19. Findings: A properly balanced diet provides acceptable amount nutrients body. Deficiency excessive individual’s may cause or abnormal conditions. An improper be responsible occurrence deficiencies iron, calcium, iodine. Minerals like boron, cobalt, phosphorous, K, E, A, D, Riboflavin can cure treat fatal Alzheimer’s, bone development conditions, osteoporosis, anemia, inflammatory bowel, HIV Infections. Conclusion: essential metabolism tissue function. Sufficient consumption thus required, but providing additional supplements persons who do not require them detrimental. Large-scale studies varied micronutrient dosages with accurate outcome indicators needed optimize intakes different patient groups general population at large. crucial health disease.

Language: Английский

Citations

14
COVID-19 and Comorbidities: What Has Been Unveiled by Metabolomics? DOI Creative Commons
André Luiz Melo Camelo, Hans Rolando Zamora-Obando, Isabela Rocha

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(4), P. 195 - 195

Published: March 30, 2024

The COVID-19 pandemic has brought about diverse impacts on the global population. Individuals with comorbidities were more susceptible to severe symptoms caused by virus. Within crisis scenario, metabolomics represents a potential area of science capable providing relevant information for understanding metabolic pathways associated intricate interaction between viral disease and previous comorbidities. This work aims provide comprehensive description scientific production pertaining within specific context comorbidities, while highlighting promising areas exploration those interested in subject. In this review, we highlighted studies that indicated variety metabolites COVID-19. Furthermore, observed processes involved is limited due urgent need report outcomes individuals overlap two or severity hinders comprehension significance each condition. Most identified are observational, restricted number patients, challenges sample collection amidst emergent situation.

Language: Английский

Citations

4
Herbal and Dietary Supplements as Adjunctive Treatment for Mild SARS-CoV-2 Infection in Italy DOI Open Access
Anna Licata, Aurelio Seidita, Silvia Como

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(2), P. 230 - 230

Published: Jan. 9, 2025

During the COVID-19 pandemic, several observational studies proved a certain efficacy of nutraceuticals, herbal products, and other dietary supplements as adjuvant therapies used alongside antiviral drugs. Although their use has not been widespread in Italy, according to preliminary evidence, many with demonstrated immunomodulatory effects, such vitamins C D, medicines essential oils, might relieve respiratory symptoms COVID-19, since SARS-CoV-2 can activate inflammasome-mediated inflammatory signaling pathways. Other have shown that treatments, Echinacea purpurea ginseng, help alleviate reduce serum levels cytokines, which are typically overexpressed both adult pediatric patients. Further, D attenuate immune response thanks cytokine suppression ability known antimicrobial activity potential modulate T helper cell response. The strong triggered by infection is responsible for severity disease. Preliminary data also L-arginine, an endothelial-derived relaxing factor, able endothelial damage, appears be one main targets this systemic Finally, some oils isolated compounds, eucalyptol, may helpful reducing although others, menthol, recommended, it lead undervaluation clinical status patient. In narrative review, despite lack evidence field, we aimed give overview current available literature (mainly cross-sectional studies) regarding products treatment mild disease from infection. Obviously, do constitute standardized disease, but they could represent adjunctive useful when together antivirals.

Language: Английский

Citations

0
Source of dietary iron and zinc affects meat quality by altering muscular fatty acid profile, flavor substances, and metabolomics in finishing pigs DOI
Zhimei Tian, Miao Yu, Yiyan Cui

et al.

Meat Science, Journal Year: 2025, Volume and Issue: 225, P. 109813 - 109813

Published: March 22, 2025

Language: Английский

Citations

0
Functional foods and immune system: A sustainable inhibitory approach against SARS-COV-2 DOI Creative Commons

Hubza Ruatt Khan,

Rabia Sultan,

Mehvish Javeed

et al.

Antiviral Therapy, Journal Year: 2025, Volume and Issue: 30(2)

Published: March 26, 2025

Background: COVID-19 has become the center of attention since its outbreak in December 2019. Despite discovery preventive vaccine, role healthy immune system is undebatable. Functional foods are continuously hunted as a promising option for safe natural therapeutic treatment. Purpose: This review demonstrates how functional can boost host system, promote antiviral operation, and synthesize biologically effective molecules against SARS-COV-2. Research Methodology: For current review, online search was conducted nature-based boosters Conclusion: foods, alongside lifestyle, fortifies human could all help to dramatically lower cost burden COVID-19, suffering patients, mortality rates worldwide.

Language: Английский

Citations

0