Proflavine (PFH+): as a photosensitizer (PS) biocatalyst for the visible-light-induced synthesis of pyrano [2,3-d] pyrimidine scaffolds

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: March 26, 2024

A sustainable methodology for the synthesis of pyrano [2,3- d ] pyrimidine scaffolds have been developed, employing Knoevenagel-Michael tandem cyclocondensation reaction barbituric acid/1,3-dimethylbarbituric acid, malononitrile, and aryl aldehydes. This study elucidates advancement a environmentally conscious approach to synthesizing this category chemical compounds. In present investigation, novel photosensitizer comprising proflavine (PFH + ) bio-photocatalyst was employed in an aqueous medium, subjected air atmosphere at room temperature, stimulated by blue-light-emitting diode (LED) harness renewable energy. The fundamental objective initiative is utilize (PS) biocatalyst that has recently can be conveniently acquired, priced affordably. photocatalyst, demonstrates ability initiate photoinduced-electron transfer (PET) through exposure visible light. property endows photocatalyst with practical efficient method achieving high effectiveness, energy efficiency, friendly outcomes. current research endeavor examining turnover number (TON) frequency (TOF) pertaining scaffolds. Moreover, it validated cyclization gram-scale feasible various industrial settings.

Language: Английский

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Carbazole-based photocatalyst (4CzIPN) as a novel donor-acceptor fluorophore-catalyzed visible-light-induced photosynthesis of dihydropyrano[2,3-c]pyrazole scaffolds via a proton-coupled electron transfer process

Journal of Chemical Sciences, Journal Year: 2023, Volume and Issue: 135(3)

Published: July 25, 2023

Language: Английский

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Recent Advancement of 1,2,3,5‐Tetrakis(Carbazol‐9‐yl)‐4,6‐Dicyanobenzene (4‐CzIPN) in Photocatalyzed Synthesis of Heterocyclic Compounds

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(17)

Published: May 1, 2025

Abstract 4‐CzIPN is a traditional electron donor and acceptor fluorophore that uses carbazolyl as an donating dicyanobenzene withdrawing source. Its broad redox potential, high chemical resistance wide applicability makes it unique metal‐free photocatalyst. This study summarizes the recent development of photoredox catalyst for variety heterocyclic construction over last four years (2021‐2024).

Language: Английский

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Tris(hydroxymethyl)aminomethane (THAM): A recyclable and biodegradable organobase catalyst for green synthesis of 2-amino-4H-chromenes in an aqueous ethanol media

Results in Chemistry, Journal Year: 2024, Volume and Issue: 9, P. 101634 - 101634

Published: July 1, 2024

We developed a green method to create 2-amino-4H-chromenes in an environmentally-friendly and efficient way. The process uses domino Knoevenagel-Michael cyclocondensation reaction. Tris(hydroxymethyl)aminomethane (THAM) recyclable biodegradable organobase catalyst is used aqueous ethanol media, the reaction done at room temperature. Several criteria for sustainable chemistry are met by current protocol's many benefits, which include being energy-efficient; reusable, affordable, readily available precursor substances; operational simplicity; suitable quick procedure; high yields; solvent; direct work-up without column chromatographic separation; atom-economy. In addition, THAM stayed stable could be five times reducing catalytic activity, making it great solving environmental issues meeting industry needs.

Language: Английский

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Polyethylene glycol (PEG-400) as a recyclable and biodegradable reaction medium for green synthesis of 2-amino-4H-chromenes

Current Research in Green and Sustainable Chemistry, Journal Year: 2023, Volume and Issue: 7, P. 100376 - 100376

Published: Jan. 1, 2023

A helpful manufactured course to the one-pot green synthesis of 2-amino-4H-chromenes through a tandem Knoevenagel-Michael cyclocondensation reaction aldehydes, malononitrile, and resorcinol in polyethylene glycol (PEG-400) as accessible biodegradable media have been detailed. All responses are completed brief time items gotten fabulous yields. The striking highlights this eco-friendly approach media, yields, simple work-up without requires for column chromatographic separation, no poisonous organic solvents, evasion harmful reagents, strategy, effortlessness operation. Additionally, PEG-400 is exceedingly steady can be reused four sequential runs major basic changes or misfortune movement, which has exceptionally advantageous tending natural concerns.

Language: Английский

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Ethylene Glycol as a Reusable and Biodegradable Solvent for the Synthesis of 2-Amino-4H-chromenes

Organic Preparations and Procedures International, Journal Year: 2023, Volume and Issue: 56(2), P. 169 - 174

Published: Aug. 8, 2023

Click to increase image sizeClick decrease size AcknowledgmentsWe gratefully acknowledge financial support from the Research Council of Apadana Institute Higher Education.Disclosure statementNo potential conflict interest was reported by author(s).

Language: Английский

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Acridine Yellow G: A Photo-induced Electron Transfer Photocatalyst for the Radical Synthesis of Pyrano[2,3- d ]pyrimidines in an Aqueous Medium

Organic Preparations and Procedures International, Journal Year: 2024, Volume and Issue: 56(5), P. 419 - 428

Published: Feb. 7, 2024

Language: Английский

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Green Synthetic Approach for Catalyst-free Synthesis of 2-Amino-4 H -chromenes Promoted by Glycerol as a Reusable Medium

Organic Preparations and Procedures International, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 7

Published: June 5, 2024

Language: Английский

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Carboxymethyl Cellulose as a Recyclable and Biodegradable Heterogeneous Catalyst for Convenient Synthesis of 2-Amino-4 H -chromenes

Organic Preparations and Procedures International, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 7

Published: Aug. 2, 2024

Language: Английский

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1,1,1,3,3,3-hexafluoro-2-propanol as a reusable media: Green and catalyst-free synthesis of pyrano[2,3-d]pyrimidine scaffolds

Journal of Chemical Sciences, Journal Year: 2024, Volume and Issue: 137(1)

Published: Dec. 14, 2024

Language: Английский

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